Functionalization of 2-Mercapto-5-methyl-1,3,4-thiadiazole: 2-(ω-Haloalkylthio) Thiadiazoles vs. Symmetrical Bis-Thiadiazoles DOI Creative Commons

Zhanina S. Petkova,

Rusi Rusew, Boris Shivachev

и другие.

Molecules, Год журнала: 2024, Номер 29(9), С. 1938 - 1938

Опубликована: Апрель 24, 2024

A study on the functionalisation of 2-mercapto-5-methyl-1,3,4-thiadiazole has been conducted, yielding two series products: 2-(ω-haloalkylthio)thiadiazoles and symmetrical bis-thiadiazoles, with variable chain lengths. The experimental conditions were optimised for each class compounds by altering base used reagents’ proportions, leading to development separate protocols tailored their specific reactivity purification needs. target halogenide reagents bis-thiadiazole ligands obtained either as single products or mixtures easily separable chromatography. Characterisation was performed using 1D 2D NMR spectra in solution, complemented crystal X-ray diffraction (XRD) selected samples, elucidate structural properties.

Язык: Английский

Recent advances on cross-coupling of alcohols via borrowing hydrogen catalysis DOI

Suteerna Mullick,

Adrija Ghosh, Debasis Banerjee

и другие.

Chemical Communications, Год журнала: 2024, Номер 60(30), С. 4002 - 4014

Опубликована: Янв. 1, 2024

This article highlights the recent advances and significance of β-alkylation reactions towards synthesis higher order alcohols.

Язык: Английский

Процитировано

14

Ruthenium-catalyzed β-alkylation of secondary alcohols with primary alcohols: Protic N-heterocyclic carbene's promotional influence DOI
Jing Shi,

Lizhu Zhang,

Panpan Li

и другие.

Journal of Molecular Structure, Год журнала: 2024, Номер 1305, С. 137815 - 137815

Опубликована: Фев. 17, 2024

Язык: Английский

Процитировано

3

Diastereoselective Synthesis of Sulfoxide‐Functionalized N‐Heterocyclic Carbene Ruthenium Complexes: An Experimental and Computational Study DOI Creative Commons

Victoria Mechrouk,

Baptiste Leforestier,

Weighang Chen

и другие.

Chemistry - A European Journal, Год журнала: 2024, Номер 30(46)

Опубликована: Июнь 12, 2024

The synthesis of sulfoxide-functionalized NHC ligand precursors were carried out by direct and mild oxidation from corresponding thioether with high selectivity. Using these salts, a series cationic [Ru(II)(η

Язык: Английский

Процитировано

2

N‐Heterocyclic Carbene Complexes RuII(Arene) and their Application as ROMP Catalysts, Antioxidant and Anticancer Agents DOI
Rubina Troiano, Domenico Iacopetta, Assunta D’Amato

и другие.

European Journal of Inorganic Chemistry, Год журнала: 2024, Номер 27(34)

Опубликована: Авг. 16, 2024

Abstract N‐Heterocyclic carbenes (NHCs) play an important role in metal complex catalysis and stabilisation, providing stability under non‐inert conditions a high σ‐donor capacity. They are crucial ligands for the synthesis of organometallic compounds like Ru II ‐complexes, which can operate as very active catalysts variety chemical transformations functionalizations. RA(Ruthenium‐arene)NHC complexes, known their piano‐stool structure, stabilise Ru(II) oxidation state by occupying three ruthenium coordination sites with η 6 ‐coordinated arene ligand. The development dual‐acting ‐arene complexes has sparked increased interest catalytic biological properties. Because broad spectrum, give distinct mechanisms pharmacological action from organic drugs. This study aimed to explore impact ligand amphiphilicity counterion on bioactivity, designing family NHC bearing ester moiety switching wingtip substituent methyl benzyl units. All synthesized were tested norbornene ROMP, benchmark reaction potential anticancer antioxidant compounds.

Язык: Английский

Процитировано

1

Synthesis and reactivity of isomeric Ru complexes with hydroxypyridyl fragment: active catalysts for β‑alkylation of secondary alcohols with primary alcohols DOI
Jing Shi, Panpan Li, Chunjian Qi

и другие.

Journal of Molecular Structure, Год журнала: 2024, Номер 1321, С. 140159 - 140159

Опубликована: Сен. 23, 2024

Язык: Английский

Процитировано

1

Recent Progress in Developing Thioether-Containing Ligands for Catalysis Applications DOI
Stéphane Bellemin‐Laponnaz, Thierry Achard

Synthesis, Год журнала: 2023, Номер 56(09), С. 1369 - 1380

Опубликована: Окт. 17, 2023

Abstract The ligand that stabilizes the metal center is crucial to its catalytic activity. Historically dominated by phosphorus and nitrogen, sulfur has long been little considered as a hetero element for stabilizing potentially active center. However, this situation changing we are seeing more examples incorporate element. This review provides an overview of recent transition-metal-catalyzed reactions with ligands containing neutral groups, i.e. thioethers. A selection published since 2013 illustrates diversity applications thioether-containing shows should be widely used in development homogeneous catalysis. 1 Introduction 2 Phosphorus-Thioether Ligands 3 Nitrogen-Thioether 4 Oxygen-Thioether 5 NHC-Thioether 6 Cycloolefin-Thioether 7 Conclusion

Язык: Английский

Процитировано

2

Synthesis and Crystal Structure of a Chelating N-Heterocyclic Carbene Palladium Complex Containing N-(3-Bromopropyl)-N’-thioether di-functionalized Imidazol-2-ylidene DOI
Yongmei Xiao, Yaowen Liu, Liangru Yang

и другие.

Journal of Chemical Crystallography, Год журнала: 2024, Номер 54(3), С. 197 - 202

Опубликована: Апрель 8, 2024

Язык: Английский

Процитировано

0

Functionalization of 2-Mercapto-5-methyl-1,3,4-thiadiazole: 2-(ω-Haloalkylthio) Thiadiazoles vs. Symmetrical Bis-Thiadiazoles DOI Creative Commons

Zhanina S. Petkova,

Rusi Rusew, Boris Shivachev

и другие.

Molecules, Год журнала: 2024, Номер 29(9), С. 1938 - 1938

Опубликована: Апрель 24, 2024

A study on the functionalisation of 2-mercapto-5-methyl-1,3,4-thiadiazole has been conducted, yielding two series products: 2-(ω-haloalkylthio)thiadiazoles and symmetrical bis-thiadiazoles, with variable chain lengths. The experimental conditions were optimised for each class compounds by altering base used reagents’ proportions, leading to development separate protocols tailored their specific reactivity purification needs. target halogenide reagents bis-thiadiazole ligands obtained either as single products or mixtures easily separable chromatography. Characterisation was performed using 1D 2D NMR spectra in solution, complemented crystal X-ray diffraction (XRD) selected samples, elucidate structural properties.

Язык: Английский

Процитировано

0