Beilstein Journal of Organic Chemistry,
Год журнала:
2023,
Номер
19, С. 1146 - 1154
Опубликована: Июль 31, 2023
Sustainable
oxidation
protocols
aim
to
provide
an
environmentally
friendly
and
cost-effective
method
for
the
production
of
various
chemicals
materials.
The
development
such
can
lead
reduced
energy
consumption,
fewer
harmful
byproducts,
increased
efficiency
in
industrial
processes.
As
such,
this
field
research
is
great
importance
interest
both
academia
industry.
This
work
showcases
a
sustainable
catalyst-free
heteroatoms
(e.g.,
S,
P,
Se)
using
only
air,
water
light.
An
additional
reaction
pathway
proposed
which
incorporated
oxygen
on
originates
from
water.
Furthermore,
addition
certain
additives
enhances
productivity
by
affecting
kinetics.
potential
demonstrated
conveniently
transferring
batch
protocol
continuous
flow
HANU
reactor,
indicating
scalability
improving
safety.
Herein,
we
present
a
nickel-catalyzed
C–S
cross-coupling
between
aryl
halides
and
ketene
dithioacetals
under
"base-free"
conditions
without
an
exogenous
ligand.
By
employing
easily
available
as
sulfide
donors,
this
reaction
affords
broad
range
of
unsymmetrical
alkyl-aryl
sulfides
using
odorous
toxic
thiols.
The
newly
developed
catalytic
methodology
features
excellent
functional
group
tolerance,
wide
substrate
scope,
diverse
downstream
synthesis.
Preliminary
mechanism
investigations
reveal
that
Ni(I)/Ni(III)
cycle
might
be
involved.
The Journal of Organic Chemistry,
Год журнала:
2021,
Номер
86(19), С. 13790 - 13799
Опубликована: Сен. 22, 2021
The
oxidation
of
diaryl
sulfides
and
aryl
alkyl
to
the
corresponding
sulfoxides
sulfones
under
electrochemical
conditions
is
reported.
Sulfoxides
are
selectively
obtained
in
good
yield
a
constant
current
5
mA
for
10
h
DMF,
while
formed
as
major
product
or
20
MeOH.
oxygen
both
sulfoxide
sulfone
function
derived
from
water.
Green Chemistry,
Год журнала:
2022,
Номер
24(12), С. 4772 - 4777
Опубликована: Янв. 1, 2022
An
electrochemical
protocol
for
the
selective
oxidation
of
sulfides
to
sulfoxides
has
been
developed
in
which
NaCl
plays
a
dual
role:
(1)
as
an
electrolyte
transformations
and
(2)
redox
mediator
avoid
sensitive
functional
groups.
Advanced Functional Materials,
Год журнала:
2024,
Номер
unknown
Опубликована: Окт. 25, 2024
Abstract
The
meticulous
design
of
highly
efficient
indirect
electrocatalysts
with
value‐added
conversion
properties
remains
a
substantial
challenge
within
the
realm
organic
catalysis.
While
polyoxometalates
(POMs)
serve
as
crucial
active
centers
in
catalytic
modeling
systems
for
chemical
materials,
their
exploration
electrocatalytic
molecular
transformations
is
hindered
by
kinetic
barriers.
Therefore,
an
protocol
established
synthesis
utilizing
polyoxomolybdates
(CuMo
6
)
immobilized
on
aerogel
foams
(CMC).
electrical
conductivity
and
activities
electrocatalyst
/CNT@CMC)
can
be
readily
enhanced
adjusting
microenvironment
between
CuMo
CMC
using
carbon
nanotubes
(CNT).
Controlled
experiments
demonstrate
that
/CNT@CMC
oxidation
sulfide
achieves
impressive
Faradaic
Efficiency
(FE)
exceeding
95%
under
ambient
conditions,
while
working
potential
markedly
lower
than
reported
heterogeneous
electrocatalysts.
Combined
experimental
theoretical
analyses
suggest
modulated
electronic
synergistic
interaction
Cu‐assisted
Mo
sites
CNT
foam
favors
appropriate
binding
PhCH
3
S
+•
intermediates,
thereby
promoting
selective
sulfides.
This
study
paves
way
utilization
polyoxometalate‐based
materials
simple
methods
various
applications.
Organic Chemistry Frontiers,
Год журнала:
2022,
Номер
9(10), С. 2664 - 2670
Опубликована: Янв. 1, 2022
Two
protocols
are
established
to
the
synthesis
of
ketones
by
oxidative
cleavage
C-C
bonds
vicinal
diols
under
electrochemical
and
thermochemical
strategies.
The
substrate
scopes
preliminary
mechanisms
these
two
discussed.
Organic Letters,
Год журнала:
2023,
Номер
25(32), С. 6001 - 6005
Опубликована: Авг. 7, 2023
An
electrochemical
facilitated
three-component
trifluoromethylation/spirocyclization
reaction
of
N-(arylsulfonyl)acrylamides,
CF3SO2Na,
and
H2O
has
been
developed.
Without
the
requirement
chemical
oxidants,
a
number
unexplored
trifluoromethylated
4-azaspiro[4.5]decanes
were
obtained
in
satisfactory
yields
under
mild
conditions.
This
work
provides
new
synthetic
strategy
for
fluorine-containing
spirocyclic
compounds
shows
perspective
reactivity
study
N-(arylsulfonyl)acrylamides.
ACS Catalysis,
Год журнала:
2024,
Номер
14(2), С. 907 - 920
Опубликована: Янв. 4, 2024
Implementation
of
an
organic
molecular
photocatalyst
for
photoelectrochemical
(PEC)
transformations
has
been
a
highly
demanding
aspect
that
not
yet
mapped
out
extensively.
Herein,
we
have
unveiled
the
efficacy
phenalenyl-based
toward
intramolecular
C–S
bond
construction
reactions
under
mild
conditions.
This
phenalenyl
core,
which
contains
vacant
NBMO,
acts
as
electron
reservoir,
thereby
facilitating
formation
contact
ion
pair
with
electron-rich
systems
through
transfer
photoexcitation
and
aiding
in
catalytic
regeneration
by
anodic
oxidation
single
pot.
Detailed
mechanistic
investigation
using
UV–visible
spectral
analysis,
cyclic
voltammetry
experiments,
computational
calculations
revealed
prior
EDA
complex
between
substrate
triggers
this
PEC
process.
unified
strategy
was
successfully
implemented
six
different
to
synthesize
heterocycles
make
protocol
appealing
synthesis
bonds.
Advanced Synthesis & Catalysis,
Год журнала:
2022,
Номер
364(14), С. 2443 - 2448
Опубликована: Июнь 4, 2022
Abstract
The
chemoselective
electrochemical
oxygenation
of
sulfides
to
sulfoxides
is
performed
using
a
biomimetic
flavin
catalyst
that
enables
the
activation
molecular
oxygen
under
low
cathode
potential.
Diverse
functional
groups,
including
alcohols,
ketones,
aldehydes,
cyclopropane,
carboxylic
acids,
pyridine,
alkenes,
and
alkynes,
are
well
tolerated
low‐voltage
electrolytic
conditions.
magnified
image
