RSC Advances,
Год журнала:
2025,
Номер
15(5), С. 3928 - 3953
Опубликована: Янв. 1, 2025
This
review
studies
magnetically
recoverable
catalysts
designed
for
the
efficient
multicomponent
synthesis
of
organosulfur
compounds.
These
enhance
process
by
combining
efficiency
with
environmental
sustainability.
Chemical Communications,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 1, 2025
We
report
an
organophotocatalyst-enabled
oxidant-free
C–S/C–Se
bond
coupling
of
(un)symmetrical
1,2-diketones
via
pro-aromatic
dihydroquinazolinones/benzothiazolines,
employing
readily
accessible
disulfides/diselenides.
Angewandte Chemie International Edition,
Год журнала:
2024,
Номер
63(20)
Опубликована: Март 12, 2024
Abstract
Cumulenes
and
heterocumulenes
with
three
or
more
cumulative
multiple
bonds
are
usually
reactive
species
that
serve
as
valuable
building
blocks
for
complex
molecules
but
tend
to
isomerize
cyclize
therefore
difficult
isolate.
Using
a
mild
ligand
exchange
reaction
at
the
carbon
in
α‐metalated
ylides,
we
have
now
succeeded
synthesis
gram‐scale
isolation
of
elusive
cyanoketenyl
anion
[NC
3
O]
−
.
Despite
its
assumed
cumulene‐like
structure
delocalization
negative
charge
across
whole
5‐atom
molecule,
it
features
bent
geometry
nucleophilic
central
atom.
Computational
studies
reveal
an
ambiguous
bonding
situation
anion,
which
can
be
illustrated
only
by
combination
different
resonance
structures.
Nonetheless,
remarkable
stability,
thus
allowing
storage
potassium‐crown
ether
salt
application
highly
functional
synthetic
block.
The
readily
reacts
series
small
form
organic
compounds,
including
industrially
compounds
such
cyanoacetate.
This
work
demonstrated
generated
novel
methods
open
up
atom‐economic
pathways
from
abundant
molecules.
Organic Letters,
Год журнала:
2023,
Номер
26(14), С. 2745 - 2750
Опубликована: Июнь 26, 2023
In
this
Communication,
an
investigation
of
the
combination
N,N,N′,N′-tetramethylchloroformamidinium
hexafluorophosphate
(TCFH)
and
N-methylimidazole
(NMI)
for
synthesis
esters
thioesters
is
described.
This
work
revealed
unique
challenges
reactions
less
nucleophilic
alcohols
more
reactive
thiols
with
N-acyl
imidazolium
intermediate
led
to
identification
general
enabling
conditions
that
provide
high
yields
selectivity
a
range
thiols.
The Journal of Organic Chemistry,
Год журнала:
2023,
Номер
88(13), С. 8628 - 8635
Опубликована: Июнь 9, 2023
A
green
method
to
construct
C-S
bonds
using
sulfonyl
chlorides
and
alcohols/acids
via
a
PIII/PV═O
catalytic
system
is
reported.
The
organophosphorus-catalyzed
umpolung
reaction
promotes
us
propose
the
"dual-substrate
deoxygenation"
strategy.
Herein,
we
adopt
strategy,
which
achieves
deoxygenation
of
synthesize
thioethers/thioesters
driven
by
redox
cycling.
represents
an
operationally
simple
approach
stable
phosphine
oxide
as
precatalyst
shows
broad
functional
group
tolerance.
potential
application
this
protocol
demonstrated
late-stage
diversification
drug
analogues.
The Journal of Organic Chemistry,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 12, 2025
An
efficient
organophosphorus-catalyzed
thiocarbonylation
reaction
of
disulfides
with
carboxylic
acids
under
air
conditions
was
described.
Various
functional
groups
on
and
can
be
tolerated
the
present
conditions,
affording
thioesters
in
good
to
excellent
yields.
This
method
exhibited
chemoselectivity
applied
for
late-stage
functionalization
drug
molecules
containing
a
acid
group.
A
new
protocol
for
preparing
thioesters
from
the
corresponding
methyl
esters
was
developed
using
i
PrMgCl
and
odorless
1-dodecanthiol,
n
C12H25SH,
under
mild
reaction
conditions,
during
which
in
situ-generated
C12H25SMgCl
selectively
reacted
with
carbonyl
group
of
esters.
variety
aromatic
aliphatic
were
readily
converted
up
to
99%
yield
excellent
functional
tolerance.
Furthermore,
based
on
quantitative
formation
thioesters,
we
successfully
applied
our
method
a
one-pot
synthesis
ketones
aldehydes
