Elsevier eBooks, Год журнала: 2024, Номер unknown
Опубликована: Янв. 1, 2024
Язык: Английский
Organic Process Research & Development, Год журнала: 2024, Номер 28(5), С. 1877 - 1885
Опубликована: Март 1, 2024
The burgeoning interest in new electrochemical methods holds promise to provide a plethora of strategic disconnections for pharmaceutical compounds that are safer, less wasteful, and more streamlined than traditional chemical strategies. use organic electrochemistry the commercial production pharmaceuticals is exceedingly rare due lack modular infrastructure. Herein we describe cascading continuous stirred tank reactors with individual cell potential control applied over reaction "stages" which demonstrate balance between high selectivity throughput necessary be viable strategy space. Using degree afforded by this reactor design, 1 kg demonstration was achieved 9 h yield (2.6 kg/day throughput).
Язык: Английский
Процитировано
9
Green Chemistry, Год журнала: 2024, Номер 26(10), С. 5862 - 5868
Опубликована: Янв. 1, 2024
Peroxodicarbonate, a sustainable electrochemically generated oxidizer, provides the means to transform abundant hydroxybenzaldehydes into valuable phenols in safe and effective manner.
Язык: Английский
Процитировано
6
Organic Letters, Год журнала: 2024, Номер 26(8), С. 1607 - 1611
Опубликована: Фев. 16, 2024
Electrochemically generated green platform oxidizers like peroxodicarbonate (PODIC) constitute a game-changing technology in terms of sustainable chemistry while serving as an alternative counterreaction the electrochemical hydrogen evolution. Peroxodicarbonate avoids storage and shipping concentrated peroxide solution. We herein disclose efficient method for N-oxidation quinolines, pyridines, complex tertiary amines. The use phenoyloxy succinimide (POSI) is decisive factor obtaining N-oxides (28 examples) isolated yields up to 98%.
Язык: Английский
Процитировано
6
Chemical Communications, Год журнала: 2024, Номер 60(56), С. 7136 - 7147
Опубликована: Янв. 1, 2024
Peroxodicarbonate, accessible from direct anodic conversion of alkali carbonates, has experienced a renaissance in the past two decades. An overview its history, synthesis, characteristics and reactivity is provided.
Язык: Английский
Процитировано
4
ACS Sustainable Chemistry & Engineering, Год журнала: 2024, Номер 12(30), С. 11283 - 11296
Опубликована: Июль 18, 2024
A pilot scale plant at Technology Readiness Level (TRL) 6 comprising an electrochemical ex-cell continuous production of sodium peroxodicarbonate and a thermal depolymerization plug flow reactor for kraft lignin conversion is established. Due to the labile nature "green" oxidizer peroxodicarbonate, special attention must be paid parameters in order optimize its use. simplified design model describing steady-state transient operations formulated finally validated against experimental data from electrolysis setup. Design trade-offs are visualized, their impact on specific energy consumption evaluated. The was operated 20-month period more than 1200 h on-stream. Optimized process conditions result vanillin yields 8 wt % thus prove successful scale-up.
Язык: Английский
Процитировано
4
RSC Sustainability, Год журнала: 2024, Номер 2(7), С. 1963 - 1968
Опубликована: Янв. 1, 2024
A halogen-free bleaching of shellac was developed using electrochemically generated peroxodicarbonate with acetonitrile as an activator. reduced damage is obtained compared to previous reports.
Язык: Английский
Процитировано
1
Опубликована: Окт. 25, 2023
The burgeoning interest in new electrochemical methods holds promise to provide a plethora of strategic disconnections for pharmaceutical compounds, which are safer, less wasteful, and more streamlined than traditional chemical strategies. use organic electrochemistry the commercial production pharmaceuticals is exceedingly rare due lack modular infrastructure. Herein, we describe cascading continuous-stirred tank reactors (CSTRs) with individual cell potential control applied over reaction ‘stages’ demonstrate balance between high selectivity throughput necessary be viable strategy space. Using degree afforded by this reactor design, 1 kg demonstration was achieved 9 hours yield (2.6 kg/day throughput).
Язык: Английский
Процитировано
2
Jurnal Sylva Lestari, Год журнала: 2023, Номер 12(1), С. 100 - 112
Опубликована: Дек. 21, 2023
Lampung is the third largest producer of nutmeg (Myristica fragrans) in Sumatra Island, Indonesia. Most essential oil refining industries process seeds, but not many distill leaves. Therefore, it necessary to identify chemical compounds determine potential for further processing products and quality oil. The leaf samples were obtained from a industry Pesawaran, Lampung, oils identified using gas chromatography-mass spectrometry. Nutmeg was then evaluated according SNI 06-2388-2006 as standard testing data analyzed descriptively. results 28 active Compounds with high relative abundance streptamine (76.46%), aquinolizine (4.67%), boron (3.73%), kaurene (2.03%), pyrrole (1.95%), naphthalene. There also terpenoid that produced aromas, such guaiol, borneol, cedrene, cubenol, spathulenol. assessment fulfilled requirement 06-2388-2006. However, optical rotation towards left, namely -9.48°, specific gravity 0.87, less than 0.88. has become raw material health beauty products. Keywords: agroforestry, oil, leaves, streptamine,
Язык: Английский
Процитировано
1
Nachrichten aus der Chemie, Год журнала: 2024, Номер 72(3), С. 44 - 67
Опубликована: Фев. 29, 2024
Abstract Unter anderem das hat die Organik im letzten Jahr bewegt: milde Oxidation mit Elektrochemie, zu enantiomerenreinen Sulfonylverbindungen, Flüssigkristallphasen erkennen maschinellem Lernen, CO 2 reagiert Succinat und Carbamaten, eine Alternative Bisphenol A, Subporphyrine, photoschaltbare Spinmaterialien, photochemische Thiophen‐Ringerweiterung, Peptide werden Bor versehen cyclisiert. Die Zusammenstellung des Trendberichts koordiniert Martin Breugst, Universität Chemnitz.
Процитировано
0
Russian Journal of General Chemistry, Год журнала: 2024, Номер 94(4), С. 743 - 748
Опубликована: Апрель 1, 2024
Язык: Английский
Процитировано
0