Tools of Green Synthesis: Electrochemistry DOI
Elisabeth K. Oehl,

Marola S. Lenhard,

Siegfried R. Waldvogel

et al.

Elsevier eBooks, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

Language: Английский

A Scalable Solution to Constant-Potential Flow Electrochemistry DOI
Jeremy Griffin, Kaid C. Harper, Simon Velasquez Morales

et al.

Organic Process Research & Development, Journal Year: 2024, Volume and Issue: 28(5), P. 1877 - 1885

Published: March 1, 2024

The burgeoning interest in new electrochemical methods holds promise to provide a plethora of strategic disconnections for pharmaceutical compounds that are safer, less wasteful, and more streamlined than traditional chemical strategies. use organic electrochemistry the commercial production pharmaceuticals is exceedingly rare due lack modular infrastructure. Herein we describe cascading continuous stirred tank reactors with individual cell potential control applied over reaction "stages" which demonstrate balance between high selectivity throughput necessary be viable strategy space. Using degree afforded by this reactor design, 1 kg demonstration was achieved 9 h yield (2.6 kg/day throughput).

Language: Английский

Citations

9
E-Dakin reaction: oxidation of hydroxybenzaldehydes to phenols with electrochemically generated peroxodicarbonate as sustainable ex-cell oxidizer DOI Creative Commons
Fiona Sprang, Niclas Schupp, Philipp J. Kohlpaintner

et al.

Green Chemistry, Journal Year: 2024, Volume and Issue: 26(10), P. 5862 - 5868

Published: Jan. 1, 2024

Peroxodicarbonate, a sustainable electrochemically generated oxidizer, provides the means to transform abundant hydroxybenzaldehydes into valuable phenols in safe and effective manner.

Language: Английский

Citations

6
Synthesis of Aromatic N-Oxides Using Electrochemically Generated Peroxodicarbonate DOI
Philipp J. Kohlpaintner, Niclas Schupp,

Niklas Ehlenz

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: 26(8), P. 1607 - 1611

Published: Feb. 16, 2024

Electrochemically generated green platform oxidizers like peroxodicarbonate (PODIC) constitute a game-changing technology in terms of sustainable chemistry while serving as an alternative counterreaction the electrochemical hydrogen evolution. Peroxodicarbonate avoids storage and shipping concentrated peroxide solution. We herein disclose efficient method for N-oxidation quinolines, pyridines, complex tertiary amines. The use phenoyloxy succinimide (POSI) is decisive factor obtaining N-oxides (28 examples) isolated yields up to 98%.

Language: Английский

Citations

6
Peroxodicarbonate – A Renaissance of an Electrochemically Generated Green Oxidizer DOI Creative Commons
Theresa Rücker, Niclas Schupp, Fiona Sprang

et al.

Chemical Communications, Journal Year: 2024, Volume and Issue: 60(56), P. 7136 - 7147

Published: Jan. 1, 2024

Peroxodicarbonate, accessible from direct anodic conversion of alkali carbonates, has experienced a renaissance in the past two decades. An overview its history, synthesis, characteristics and reactivity is provided.

Language: Английский

Citations

4
Pilot Scale Electrolysis of Peroxodicarbonate as an Oxidizer for Lignin Valorization DOI Creative Commons
Theresa Rücker, Torbjørn Pettersen,

Hannah Graute

et al.

ACS Sustainable Chemistry & Engineering, Journal Year: 2024, Volume and Issue: 12(30), P. 11283 - 11296

Published: July 18, 2024

A pilot scale plant at Technology Readiness Level (TRL) 6 comprising an electrochemical ex-cell continuous production of sodium peroxodicarbonate and a thermal depolymerization plug flow reactor for kraft lignin conversion is established. Due to the labile nature "green" oxidizer peroxodicarbonate, special attention must be paid parameters in order optimize its use. simplified design model describing steady-state transient operations formulated finally validated against experimental data from electrolysis setup. Design trade-offs are visualized, their impact on specific energy consumption evaluated. The was operated 20-month period more than 1200 h on-stream. Optimized process conditions result vanillin yields 8 wt % thus prove successful scale-up.

Language: Английский

Citations

4
Halogen-Free Bleaching of Shellac Using Electrochemically Generated Peroxodicarbonate DOI Creative Commons
Tomas Horsten, Siegfried R. Waldvogel

RSC Sustainability, Journal Year: 2024, Volume and Issue: 2(7), P. 1963 - 1968

Published: Jan. 1, 2024

A halogen-free bleaching of shellac was developed using electrochemically generated peroxodicarbonate with acetonitrile as an activator. reduced damage is obtained compared to previous reports.

Language: Английский

Citations

1
A Scalable Solution to Constant Potential Flow Electrochemistry DOI Creative Commons
Jeremy Griffin, Kaid C. Harper,

S. Restrepo Velásquez

et al.

Published: Oct. 25, 2023

The burgeoning interest in new electrochemical methods holds promise to provide a plethora of strategic disconnections for pharmaceutical compounds, which are safer, less wasteful, and more streamlined than traditional chemical strategies. use organic electrochemistry the commercial production pharmaceuticals is exceedingly rare due lack modular infrastructure. Herein, we describe cascading continuous-stirred tank reactors (CSTRs) with individual cell potential control applied over reaction ‘stages’ demonstrate balance between high selectivity throughput necessary be viable strategy space. Using degree afforded by this reactor design, 1 kg demonstration was achieved 9 hours yield (2.6 kg/day throughput).

Language: Английский

Citations

2
Characterization of Leaf Essential Oil from Nutmeg (Myristica fragrans) Cultivated on Agroforestry Land DOI Creative Commons

Widia Rini Hartari,

Sri Hidayati, Tanto Pratondo Utomo

et al.

Jurnal Sylva Lestari, Journal Year: 2023, Volume and Issue: 12(1), P. 100 - 112

Published: Dec. 21, 2023

Lampung is the third largest producer of nutmeg (Myristica fragrans) in Sumatra Island, Indonesia. Most essential oil refining industries process seeds, but not many distill leaves. Therefore, it necessary to identify chemical compounds determine potential for further processing products and quality oil. The leaf samples were obtained from a industry Pesawaran, Lampung, oils identified using gas chromatography-mass spectrometry. Nutmeg was then evaluated according SNI 06-2388-2006 as standard testing data analyzed descriptively. results 28 active Compounds with high relative abundance streptamine (76.46%), aquinolizine (4.67%), boron (3.73%), kaurene (2.03%), pyrrole (1.95%), naphthalene. There also terpenoid that produced aromas, such guaiol, borneol, cedrene, cubenol, spathulenol. assessment fulfilled requirement 06-2388-2006. However, optical rotation towards left, namely -9.48°, specific gravity 0.87, less than 0.88. has become raw material health beauty products. Keywords: agroforestry, oil, leaves, streptamine,

Language: Английский

Citations

1
Trendbericht Organische Chemie 2024 DOI Open Access
Martin Breugst, Jennifer N. Andexer,

Lena Barra

et al.

Nachrichten aus der Chemie, Journal Year: 2024, Volume and Issue: 72(3), P. 44 - 67

Published: Feb. 29, 2024

Abstract Unter anderem das hat die Organik im letzten Jahr bewegt: milde Oxidation mit Elektrochemie, zu enantiomerenreinen Sulfonylverbindungen, Flüssigkristallphasen erkennen maschinellem Lernen, CO 2 reagiert Succinat und Carbamaten, eine Alternative Bisphenol A, Subporphyrine, photoschaltbare Spinmaterialien, photochemische Thiophen‐Ringerweiterung, Peptide werden Bor versehen cyclisiert. Die Zusammenstellung des Trendberichts koordiniert Martin Breugst, Universität Chemnitz.

Citations

0
Pd-Catalyzed Hydrogenation of Unsaturated Terpenoids in Two-Chamber Reactors DOI
Yulia V. Gyrdymova

Russian Journal of General Chemistry, Journal Year: 2024, Volume and Issue: 94(4), P. 743 - 748

Published: April 1, 2024

Language: Английский

Citations

0