Sustainable synthesis of thiosulfonates and disulfides by molybdenum-catalyzed selective oxidation of thiols
Green Chemistry,
Год журнала:
2024,
Номер
26(7), С. 4161 - 4167
Опубликована: Янв. 1, 2024
We
report
a
polyoxomolybdate
([N(
n
-Bu)
4
]
Mo
8
O
26
)
for
the
selective
oxidation
of
thiols
to
thiosulfonates
and
disulfides
with
H
2
air
as
oxidant,
respectively.
Язык: Английский
Metal-free three-component tandem cyclization for modular synthesis of 2,3-dihydrobenzothiazin-4-ones
Organic Chemistry Frontiers,
Год журнала:
2024,
Номер
11(7), С. 2021 - 2026
Опубликована: Янв. 1, 2024
The
first
three-component
cyclization
reaction
of
benzo[
c
][1,2]dithiol-3-ones
based
on
S–S
bond
cleavage
is
disclosed
herein.
Язык: Английский
Selective C(sp3)–S Bond Cleavage of Thioethers to Build Up Unsymmetrical Disulfides
Ke Yang,
Yanqi Luo,
Qingyue Hu
и другие.
The Journal of Organic Chemistry,
Год журнала:
2023,
Номер
88(19), С. 13699 - 13711
Опубликована: Сен. 25, 2023
The
selective
C(sp3)–S
bond
cleavage
of
thioethers
was
first
developed
to
prepare
unsymmetrical
disulfides
by
using
electrophilic
halogenation
reagents.
In
this
strategy,
NBS
(N-bromosuccinimide)
achieves
furfuryl
alkylthioethers
at
room
temperature.
Meanwhile,
NFSI
(N-fluorobenzenesulfonimide)
enables
methyl
aryl
and
alkyl
methylthioethers
an
elevated
Notably,
the
substrate
scope
investigation
indicates
that
order
selectivity
C–S
is
>
benzyl
C(sp2)–S
bond.
Moreover,
practical
operationally
simple
strategy
also
provides
important
complementary
way
access
various
with
excellent
functional
group
tolerances
moderate
good
yields.
Язык: Английский
Metal‐Free and NBS‐Mediated C(sp3)−S Bond Cleavage of Thioethers to Access Alkyl Bromides
ChemistrySelect,
Год журнала:
2024,
Номер
9(14)
Опубликована: Апрель 11, 2024
Abstract
A
selective
C(sp
3
)−S
bond
cleavage
of
thioethers
mediated
by
NBS
is
developed.
Various
alkyl
bromides
have
been
obtained
in
good
yields
using
N
‐aryl‐3‐(methylthio)propanamides
and
arylmethylene
alkylthioethers.
Mechanistic
studies
suggest
that
the
formation
3‐bromo‐
‐arylpropanamides
may
involve
sulfoxide
intermediates,
while
are
formed
through
direct
bromination
process
NBS.
The
significance
this
strategy
lies
its
pioneering
use
for
C−S
subsequent
reaction.
Язык: Английский
Methanesulfenylation of mercaptans and β-dicarbonyls with DMSO
Journal of Sulfur Chemistry,
Год журнала:
2023,
Номер
45(3), С. 330 - 345
Опубликована: Дек. 7, 2023
The
methanesulfenylation
of
various
mercaptans
and
β-dicarbonyls
has
been
investigated
using
in-situ
generated
methyl
methanethiosulfonate
(MMTS)
from
DMSO,
facilitated
by
a
catalytic
amount
(COCl)2.
Employing
the
MMTS
solution
alongside
Et3N
led
to
synthesis
range
unsymmetrical
disulfides
with
good
yields.
Furthermore,
introduction
[2H6]-DMSO
enabled
successful
preparation
[2H3]-disulfides.
In
case
most
β-dicarbonyls,
was
accomplished
DBU,
resulting
in
favorable
Язык: Английский
Recent Advances in Visible Light Photocatalytic and Transition Metal-Catalyzed Synthesis of Disulfide Compounds
Organic & Biomolecular Chemistry,
Год журнала:
2024,
Номер
unknown
Опубликована: Янв. 1, 2024
Reviewing
photocatalytic
and
metal-catalyzed
disulfide
synthesis,
2021–2024,
emphasizes
efficiency,
selectivity,
sustainability
for
drug
material
science.
Язык: Английский