Recent Advances in Visible Light Photocatalytic and Transition Metal-Catalyzed Synthesis of Disulfide Compounds DOI
Jia‐Lin Tu

Organic & Biomolecular Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

Reviewing photocatalytic and metal-catalyzed disulfide synthesis, 2021–2024, emphasizes efficiency, selectivity, sustainability for drug material science.

Language: Английский

Sustainable synthesis of thiosulfonates and disulfides by molybdenum-catalyzed selective oxidation of thiols DOI
Zhibin Zhou, Hao Xu,

Jiamin Ma

et al.

Green Chemistry, Journal Year: 2024, Volume and Issue: 26(7), P. 4161 - 4167

Published: Jan. 1, 2024

We report a polyoxomolybdate ([N( n -Bu) 4 ] Mo 8 O 26 ) for the selective oxidation of thiols to thiosulfonates and disulfides with H 2 air as oxidant, respectively.

Language: Английский

Citations

9

Metal-free three-component tandem cyclization for modular synthesis of 2,3-dihydrobenzothiazin-4-ones DOI
Guan Zhang, Hui Wan, Na Dong

et al.

Organic Chemistry Frontiers, Journal Year: 2024, Volume and Issue: 11(7), P. 2021 - 2026

Published: Jan. 1, 2024

The first three-component cyclization reaction of benzo[ c ][1,2]dithiol-3-ones based on S–S bond cleavage is disclosed herein.

Language: Английский

Citations

3

Selective C(sp3)–S Bond Cleavage of Thioethers to Build Up Unsymmetrical Disulfides DOI
Ke Yang,

Yanqi Luo,

Qingyue Hu

et al.

The Journal of Organic Chemistry, Journal Year: 2023, Volume and Issue: 88(19), P. 13699 - 13711

Published: Sept. 25, 2023

The selective C(sp3)–S bond cleavage of thioethers was first developed to prepare unsymmetrical disulfides by using electrophilic halogenation reagents. In this strategy, NBS (N-bromosuccinimide) achieves furfuryl alkylthioethers at room temperature. Meanwhile, NFSI (N-fluorobenzenesulfonimide) enables methyl aryl and alkyl methylthioethers an elevated Notably, the substrate scope investigation indicates that order selectivity C–S is > benzyl C(sp2)–S bond. Moreover, practical operationally simple strategy also provides important complementary way access various with excellent functional group tolerances moderate good yields.

Language: Английский

Citations

4

Metal‐Free and NBS‐Mediated C(sp3)−S Bond Cleavage of Thioethers to Access Alkyl Bromides DOI

Yanqi Luo,

Dan Yuan, Qin Li

et al.

ChemistrySelect, Journal Year: 2024, Volume and Issue: 9(14)

Published: April 11, 2024

Abstract A selective C(sp 3 )−S bond cleavage of thioethers mediated by NBS is developed. Various alkyl bromides have been obtained in good yields using N ‐aryl‐3‐(methylthio)propanamides and arylmethylene alkylthioethers. Mechanistic studies suggest that the formation 3‐bromo‐ ‐arylpropanamides may involve sulfoxide intermediates, while are formed through direct bromination process NBS. The significance this strategy lies its pioneering use for C−S subsequent reaction.

Language: Английский

Citations

1

Methanesulfenylation of mercaptans and β-dicarbonyls with DMSO DOI
Xixuan Zhao, Hao Wang,

Shuting Yin

et al.

Journal of Sulfur Chemistry, Journal Year: 2023, Volume and Issue: 45(3), P. 330 - 345

Published: Dec. 7, 2023

The methanesulfenylation of various mercaptans and β-dicarbonyls has been investigated using in-situ generated methyl methanethiosulfonate (MMTS) from DMSO, facilitated by a catalytic amount (COCl)2. Employing the MMTS solution alongside Et3N led to synthesis range unsymmetrical disulfides with good yields. Furthermore, introduction [2H6]-DMSO enabled successful preparation [2H3]-disulfides. In case most β-dicarbonyls, was accomplished DBU, resulting in favorable

Language: Английский

Citations

2

Recent Advances in Visible Light Photocatalytic and Transition Metal-Catalyzed Synthesis of Disulfide Compounds DOI
Jia‐Lin Tu

Organic & Biomolecular Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

Reviewing photocatalytic and metal-catalyzed disulfide synthesis, 2021–2024, emphasizes efficiency, selectivity, sustainability for drug material science.

Language: Английский

Citations

0