Biosensors,
Год журнала:
2023,
Номер
13(4), С. 416 - 416
Опубликована: Март 23, 2023
Biosensors
are
analytical
tools
that
can
be
used
as
simple,
real-time,
and
effective
devices
in
clinical
diagnosis,
food
analysis,
environmental
monitoring.
Nanoscale
functional
materials
possess
unique
properties
such
a
large
surface-to-volume
ratio,
making
them
useful
for
biomedical
diagnostic
purposes.
Nanoengineering
has
resulted
the
increased
use
of
nanoscale
biosensors.
Various
types
nanostructures
i.e.,
0D,
1D,
2D,
3D,
have
been
intensively
employed
to
enhance
biosensor
selectivity,
limit
detection,
sensitivity,
speed
response
time
display
results.
In
particular,
carbon
nanotubes
nanofibers
extensively
electrochemical
biosensors,
which
become
an
interdisciplinary
frontier
between
material
science
viral
disease
detection.
This
review
provides
overview
current
research
activities
nanofiber-based
biosensors
The
applications
these
nanobiosensors
also
highlighted,
along
with
discussion
future
directions
diagnostics.
aim
this
is
stimulate
broader
interest
developing
improving
their
diagnosis.
review,
we
summarize
some
most
recent
advances
achieved
point
care
(PoC)
applications,
focusing
on
new
modifiers
enabling
biorecognition
led
improved
specificity,
stability,
time.
Macromolecular Materials and Engineering,
Год журнала:
2023,
Номер
309(4)
Опубликована: Ноя. 23, 2023
Abstract
In
this
study,
three
kinds
of
electrohydrodynamic
atomization
(EHDA)
processes
(electrospraying,
electrospinning,
and
coaxial
electrospinning)
are
implemented
to
create
hydroxypropyl
methylcellulose
(HPMC)
based
ultra‐thin
products
for
providing
the
fast
dissolution
a
poorly
water‐soluble
drug
ketoprofen
(KET).
An
EHDA
apparatus,
characterized
by
novel
spinneret,
is
homemade
conducting
processes.
The
types
electrospun
nanofibers
E1,
electrosprayed
microparticles
E2,
core‐shell
E3.
SEM
TEM
results
indicate
that
they
have
anticipated
morphologies
inner
structures.
X‐ray
diffraction
Fourier
Transform
Infrared
verify
KET
mainly
amorphous
in
all
composites
due
its
fine
compatibility
with
HPMC.
vitro
tests
demonstrate
rapid
release
performances
has
an
order
E3>E1>E2≫KET
powders.
mechanisms
suggested
advantages
compared.
super
performance
E3
furnishing
attributed
synergistic
action
small
size
(of
shell
thickness),
high
porosity,
state
drug,
solubility
nanostructures
can
support
development
nano
delivery
systems
(DDSs)
through
tailoring
spatial
distribution
molecules
within
products.
Advanced Healthcare Materials,
Год журнала:
2024,
Номер
13(12)
Опубликована: Янв. 31, 2024
Abstract
The
skin
serves
as
the
body's
outermost
barrier
and
is
largest
organ,
providing
protection
not
only
to
body
but
also
various
internal
organs.
Owing
continuous
exposure
external
factors,
it
susceptible
damage
that
can
range
from
simple
severe,
including
serious
types
of
wounds
such
burns
or
chronic
wounds.
Macrophages
play
a
crucial
role
in
entire
wound‐healing
process
contribute
significantly
regeneration.
Initially,
M1
macrophages
infiltrate
phagocytose
bacteria,
debris,
dead
cells
fresh
As
tissue
repair
activated,
M2
are
promoted,
reducing
inflammation
facilitating
restoration
dermis
epidermis
regenerate
tissue.
This
suggests
extracellular
matrix
(ECM)
promotes
cell
adhesion,
proliferation,
migrationand
macrophage
polarization.
Among
numerous
strategies,
electrospinning
versatile
technique
for
obtaining
ECM‐mimicking
structures
with
anisotropic
isotropic
topologies
micro/nanofibers.
Various
electrospun
biomaterials
influence
polarization
based
on
their
topologies.
Moreover,
these
fibers
possess
high
surface‐area‐to‐volume
ratio,
promoting
effective
exchange
vital
nutrients
oxygen,
which
viability
Micro/nanofibers
diverse
physical
chemical
properties
be
tailored
polarize
toward
regeneration
wound
healing,
depending
specific
requirements.
review
describes
significance
micro/nanostructures
activating
healing.
Polymers,
Год журнала:
2025,
Номер
17(4), С. 435 - 435
Опубликована: Фев. 7, 2025
Drug
delivery
systems
have
revolutionized
traditional
drug
administration
methods
by
addressing
various
challenges,
such
as
enhancing
solubility,
prolonging
effectiveness,
minimizing
adverse
effects,
and
preserving
potency.
Nanotechnology-based
systems,
particularly
nanoparticles
(NPs)
nanofibers
(NFs),
emerged
promising
solutions
for
biomedicine
delivery.
NFs,
with
their
ability
to
mimic
the
porous
fibrous
structures
of
biological
tissues,
garnered
significant
interest
in
drug-delivering
applications.
Biopolymers
gelatin
(Ge)
chitosan
(CH)
gained
much
more
attention
due
biocompatibility,
biodegradability,
versatility
biomedical
CH
exhibits
exceptional
anti-bacterial
activity,
wound
healing
capabilities,
whereas
Ge
provides
good
biocompatibility
cell
adhesion
properties.
Ge/CH-based
NFs
stimulate
cellular
connections
facilitate
tissue
regeneration
owing
structural
resemblance
extracellular
matrix.
This
review
explores
additive
preparation,
including
electrospinning,
force
pinning,
template
synthesis,
focusing
on
electrospinning
factors
influencing
fiber
structure.
The
properties
CH,
role
release,
formulation
strategies,
characterization
techniques
electrospun
fibers
are
discussed.
Furthermore,
this
addresses
applications
delivering
active
moieties
management
orthopedics
regulatory
considerations,
along
challenges
related
them.
Thus,
aims
provide
a
comprehensive
overview
potential
Advanced Engineering Materials,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 13, 2025
Electrospinning
is
a
versatile
technique
for
producing
micro‐
and
nanoscale
fibers,
offering
vast
potential
to
address
critical
market
demands,
particularly
in
biomedical
engineering.
However,
the
industrial
adoption
of
electrospinning
as
manufacturing
technology
faces
significant
hurdles,
notably
achieving
precise
control
over
fiber
properties
ensuring
reproducibility
scalability.
These
challenges
directly
impact
its
viability
creating
advanced
products.
Bridging
gap
between
material
properties,
end‐user
requirements,
process
parameters
essential
unlocking
full
electrospinning.
This
work
provides
comprehensive
review
modalities,
operational
factors,
modeling
techniques,
emphasizing
their
role
optimizing
process.
The
use
strategies
machine
learning
methods
explored,
showcasing
enhance
performance.
highlights
connection
product
performance
electrospinning,
well
necessary
conditions
applications.
In
addition,
identifies
gaps
unexplored
areas,
roadmap
future
innovation
fabrication.
By
synergy
intelligent
design
applications,
this
lays
groundwork
advancements,
positioning
cornerstone
next‐generation
technologies.
Materials Horizons,
Год журнала:
2022,
Номер
9(12), С. 2914 - 2948
Опубликована: Янв. 1, 2022
Electrochemical
power
tools,
fabricated
using
the
natural-based
electrospun
fibers,
are
regarded
as
essential
keys
in
a
world
that
is
becoming
increasingly
reliant
on
fossil
fuels
order
to
meet
challenges
of
rapidly
depleting
fuel
supplies.
Abstract
This
review
addresses
the
latest
advancements
in
integration
of
aggregation‐induced
emission
(AIE)
materials
with
polymer
electrospinning,
to
accomplish
fine‐scale
electrospun
fibers
tunable
photophysical
and
photochemical
properties.
Micro‐
nanoscale
augmented
AIE
dyes
(termed
AIEgens)
are
bespoke
composite
systems
that
can
overcome
limitation
posed
by
aggregation‐caused
quenching,
a
critical
deficiency
conventional
luminescent
materials.
comprises
three
parts.
First,
reader
is
exposed
basic
concepts
fundamental
mechanisms
underpinning
restriction
intermolecular
motions.
followed
an
introduction
electrospinning
techniques
pertinent
AIE‐based
fibers,
core
parameters
for
controlling
fiber
architecture
resultant
Second,
exemplars
drawn
from
research
demonstrate
how
nanofibers
porous
films
incorporating
modified
AIEgens
(especially
tetraphenylethylene
triphenylamine
derivatives)
yield
enhanced
photostability,
photothermal
properties,
photoefficiency
(quantum
yield),
improved
device
sensitivity.
Advanced
applications
several
promising
sectors,
encompassing
optoelectronics,
drug
delivery
biology,
chemosensors
mechanochromic
sensors,
innovative
devices,
among
others.
Finally,
outstanding
challenges
together
potential
opportunities
nascent
field
AIE‐active
presented,
stimulating
frontier
explorations
this
exciting
field.