Frontiers in Plant Science,
Год журнала:
2022,
Номер
13
Опубликована: Ноя. 29, 2022
Bacterial
fruit
blotch,
caused
by
the
seedborne
gram-negative
bacterium
Acidovorax
citrulli,
is
one
of
most
destructive
bacterial
diseases
cucurbits
(gourds)
worldwide.
Despite
its
prevalence,
effective
and
reliable
means
to
control
blotch
remain
limited.
Transcriptomic
analyses
tissue
culture-based
regeneration
processes
have
revealed
that
organogenesis-associated
cellular
reprogramming
often
associated
with
upregulation
stress-
defense-responsive
genes.
Yet,
there
limited
evidence
supporting
notion
reprogrammed
metabolism
regenerated
tissued
confers
bona
fide
antimicrobial
activity.
Here,
we
explored
anti-bacterial
activity
protocorm-like-bodies
(PLBs)
Phalaenopsis
aphrodite.
Encouragingly,
found
PLB
extract
was
potent
in
slowing
growth
A.
reducing
number
bacteria
attached
watermelon
seeds,
alleviating
disease
symptoms
seedlings
citrulli.
Because
can
be
fractionated
chemically,
predict
during
process
produces
metabolites
antibacterial
In
conclusion,
our
data
demonstrated
developing
PLBs
potential
using
orchid
discover
chemicals
disease.
Toona
is
a
critical
genus
in
the
Meliaceae,
and
plants
of
this
group
are
an
asset
for
both
restorative
purposes,
most
flexible
which
sinensis
ciliata.
To
concentrate
on
advancement
mitochondrial(Mt)
genome
variety
T.sinensis
T.ciliata,
Mt
genomes
two
species
were
sequenced
high
throughput
independently,
after
de
novo
assembly
annotation
to
construct
map
comparison
structure.
Find
their
repetitive
sequences
analyze
them
with
chloroplast
genome,
along
Maximum-likelihood(ML)
phylogenetic
analysis
16
other
relatives.(1)
T.
T.ciliata
circular
structures
lengths
683482
bp
68300
bp,
respectively.
They
share
degree
similarity
encoding
genes
have
AT
preferences.
All
largest
Phe
concentration
frequently
used
codons.
(2)
Both
highly
preserved
terms
structural
functional
genes,
while
main
variability
reflected
length
tRNA,
number
value
RSCU.
(3)
siniensis
ciliata
detected
94
87
SSRs,
respectively,
mononucleotides
accounted
absolute
proportion.
Besides,
vast
majority
SSRs
found
be
poly-A
or
poly-T.
(4)10
11
migrating
fragments
identified
(5)
In
ML
evolutionary
tree,
clustered
individually
into
small
branch
100%
support,
reflecting
very
similarly
related
each
other.This
research
provides
basis
exploitation
medicinal,
edible,
timber
resources
avoid
confusion;
at
same
time,
it
can
explore
relationship
between
species,
does
not
only
important
practical
value,
but
also
theoretical
future
hybrid
breeding
forest
trees,
molecular
markers,
aspects
plants,
has
great
scientific
significance.
Future Journal of Pharmaceutical Sciences,
Год журнала:
2023,
Номер
9(1)
Опубликована: Апрель 11, 2023
Abstract
Background
Luffa
cylindrica
(L.)
is
an
annual
climbing
plant
that
produces
fibrous
fruit
and
can
also
be
used
as
a
vegetable
in
northern
parts
of
India.
Various
studies
have
been
carried
out
on
the
found
to
anti-inflammatory,
antifungal,
analgesic,
anti-myocardial,
anti-hyper
triglyceride,
immunostimulant,
anti-allergic,
other
properties.
The
ethanolic
extract
has
not
yet
subjected
LC–MS
analysis
for
several
bioactive
chemicals
target
neurological
diseases.
Oxidative
stress
inevitable
situation
AD
mechanisms
key
bridge
connecting
various
pathways.
Results
contains
phytochemicals
showed
highest
alkaloid
content
21.39
±
1.47
mg
AE/g.
A
total
80
compounds
were
identified
from
analysis.
screened
eligibility
by
Lipinski's
rule
five
docking
with
receptors
responsible
causing
oxidative
stress-associated
Alzheimer's
disease.
Perlolyrine
was
chosen
perform
in-silico
docking.
An
vitro
activity
cholinesterase
inhibition
at
500
µg/ml.
In-silico
perlolyrine
better
binding
affinity
score.
revealed
10
docked
receptors,
amyloid
beta
energy
−
46.1
kcal/mol
showing
promising
drug
Conclusion
Based
current
findings,
study
reports
presence
promising,
compound
(perlolyrine)
turn
provides
optimistic
note
exploring
its
biological
vivo
stress-related
Molecules,
Год журнала:
2024,
Номер
29(3), С. 718 - 718
Опубликована: Фев. 4, 2024
Toona
sinensis
(A.
Juss.)
Roem.,
which
is
widely
distributed
in
China,
a
homologous
plant
resource
of
medicine
and
food.
The
leaves,
seeds,
barks,
buds
pericarps
T.
can
be
used
as
with
traditional
efficacy.
Due
to
its
extensive
use
the
ancient
world,
has
significant
development
potential.
In
this
review,
206
compounds,
including
triterpenoids
(1–133),
sesquiterpenoids
(134–135),
diterpenoids
(136–142),
sterols
(143–147),
phenols
(148–167),
flavonoids
(168–186),
phenylpropanoids
(187–192)
others
(193–206),
are
isolated
from
plant.
mass
spectrum
cracking
laws
representative
compounds
(64,
128,
129,
154–156,
175,
177,
179
183)
reviewed,
conducive
discovery
novel
active
substances.
Modern
pharmacological
studies
have
shown
that
extracts
their
antidiabetic,
antidiabetic
nephropathy,
antioxidant,
anti-inflammatory,
antitumor,
hepatoprotective,
antiviral,
antibacterial,
immunopotentiation
other
biological
activities.
uses,
chemical
constituents,
compound
activities
different
parts
laying
foundation
for
improving
utilization
medicinal
value.
Phytochemical Analysis,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 14, 2025
ABSTRACT
Introduction
Aqueous
stem
bark
extracts
of
Aspidosperma
rigidum
Rusby,
Couroupita
guianensis
Aubl.,
Monteverdia
laevis
(Reissek)
Biral,
and
Protium
sagotianum
Marchand
have
been
reported
as
traditional
remedies
in
several
countries
the
Amazonian
region.
Despite
previous
research,
further
investigation
to
characterize
secondary
metabolites
biological
activity
is
needed
derive
potential
applications.
Material
Methods
Metabolic
profiling
was
carried
out
using
liquid
gas
chromatography
coupled
with
mass
spectrometry
(UHPLC–MS/MS
GC–MS).
The
chemical
composition
studied
plants
compared
by
principal
component
analysis
(PCA).
Additionally,
profiles
were
correlated
antimicrobial
toxicity
activities,
which
suggested
for
future
research.
Results
We
identified
16
32
compounds
UHPLC–MS/MS
GC–MS
analysis,
respectively.
Antimicrobial
detected
three
extracts.
C.
showed
inhibition
all
tested
microorganisms,
including
antibiotic‐resistant
strains.
Molecular
networking
approaches,
silico
tools,
Pearson's
correlation
that
antifungal
could
be
a
terpene
glycoside
(
r
=
0.918)
and/or
phenolic
0.882)
metabolite
class.
Conclusion
This
study
highlights
use
established
procedure
exploring
metabolomes
these
species,
novel
source
drug
discovery.
Coupling
observed
data
has
also
accelerated
tracing
their
bioactive
compounds.
These
findings
update
state
art
regarding
plant
extracts,
defining
new
applications
pharmaceutical
Journal of Essential Oil Bearing Plants,
Год журнала:
2024,
Номер
27(5), С. 1377 - 1393
Опубликована: Сен. 2, 2024
AbstractToona
sinensis
is
one
of
the
traditional
Chinese
medicinal
materials
with
rich
physiological
activities.
This
study
aimed
to
investigate
chemical
composition
differences
essential
oils
from
tender
leaves
and
shoots
T.
sinensis,
collected
four
main
producing
areas
in
China,
verify
their
anti-listeria
antioxidant
properties.
Gas
chromatography-mass
spectrometry
(GC-MS)
analysis
was
conducted
on
obtained
by
hydro-distillation.
The
results
indicated
that
compounds
such
as
β-elemene
(3.5∼8.1%),
α-caryophyllene
(3.7∼7.2%),
trans-caryophyllene
(4.0∼9.7%)
were
common
components
(TSEO)
areas.
DPPH
ABTS
showed
oil
Dazhou,
Sichuan,
China
had
best
effect.
At
a
concentration
1.25
mg/mL,
activity
TSEO-DZ
Sichuan
comparable
0.08
mg/mL
BHT
only
slightly
lower
than
0.06
VC.
broth
dilution
method
Tai
'an,
Shandong,
better
antibacterial
effect,
minimum
inhibitory
(MIC)
bactericidal
(MLC)
values
μL/mL
2.54
μL/mL,
respectively.
demonstrates
TSEO
possesses
promising
application
potential
activities,
it
confirms
growth
environment
significantly
influences
quality,
content,
biological
oil.Keywords:
Antioxidant
propertiesAnti-listeria
activityEssential
oilPrincipal
component
analysisToona
Journal of Separation Science,
Год журнала:
2023,
Номер
46(8)
Опубликована: Фев. 21, 2023
Sijunzi
Decoction
is
composed
of
Ginseng
Radix
et
Rhizoma,
Atractylodes
Macrocephalae
Poria,
and
Glycyrrhizae
Et
Rhizoma
Praeparata
Cum
Melle,
it
a
classic
formula
for
treating
spleen
deficiency
syndrome
in
Chinese
medicine.
Clarifying
the
active
substances
an
effective
way
to
develop
Traditional
medicine
innovative
medicines.
Carbohydrates,
proteins,
amino
acids,
saponins,
flavonoids,
phenolic
inorganic
elements
decoction
were
analyzed
by
multiple
approaches.
A
molecular
network
was
also
used
visualizing
ingredients
Decoction,
representative
components
quantified.
The
detected
accounted
74.544%
freeze-dried
powder,
including
41.751%
crude
polysaccharides,
17.826%
sugars
(degree
polymerization
1-2),
8.181%
total
2.427%
insoluble
precipitates,
2.154%
free
1.177%
0.546%
0.483%
elements.
Molecular
quantitative
analysis
characterize
chemical
composition
Decoction.
present
study
systematically
characterized
constituents
revealed
ratio
each
type
constituent,
provided
reference
on
substance
basis
other
