Recent Progress in the Multicomponent Synthesis of Pyran Derivatives by Sustainable Catalysts under Green Conditions

Molecules, Год журнала: 2022, Номер 27(19), С. 6347 - 6347

Опубликована: Сен. 26, 2022

Pyrans are one of the most significant skeletons oxygen-containing heterocyclic molecules, which exhibit a broad spectrum medicinal applications and constituents diverse natural product analogues. Various biological these pyran analogues contributed to growth advances in molecules. Green one-pot methodologies for synthesising molecules have received attention. This review focuses on recent developments ring derivatives using reusable catalysts emphasises multicomponent reaction strategies green protocols. The advantages terms yields, conditions, recyclability discussed.

Язык: Английский

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Synthesis, computational and antimicrobial study of 2-(2-Hydrazinyl)thiazole derivatives

Journal of Molecular Structure, Год журнала: 2023, Номер 1300, С. 137096 - 137096

Опубликована: Ноя. 15, 2023

Язык: Английский

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Recent Progresses in the Multicomponent Synthesis of Dihydropyridines by Applying Sustainable Catalysts Under Green Conditions

Frontiers in Chemistry, Год журнала: 2021, Номер 9

Опубликована: Дек. 21, 2021

The synthesis of dihydropyridines, valuable molecules with diverse therapeutic properties, using eco-friendly heterogeneous catalysts as a green alternative received significant consideration. By selecting appropriate precursors, these compounds can be readily modified to induce the desired properties in target product. This review focused on synthesising dihydropyridine derivatives single-pot reactions magnetic, silica, and zirconium-based catalytic systems. monograph describes preparation techniques for various catalyst materials detail. It covers facile benign zirconium-based, ionic liquid catalysts, exhibiting efficacy consistently facilitating excellent yields short reaction times cost-effective way. Most designated protocols employ Hantzsch involving substituted aldehydes, active methylene compounds, ammonium acetate. These presumably follow Knoevenagel condensation followed by Michael addition intra-molecular cyclisation. multicomponent one-pot solvents have admirably increased product selectivity while minimising time. sustainable retain their viability several cycles reducing expenditure are eco-friendly.

Язык: Английский

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An ecofriendly and reusable catalyst RuO2/MWCNT in the green synthesis of sulfonyl-quinolines

Process Safety and Environmental Protection, Год журнала: 2022, Номер 159, С. 911 - 917

Опубликована: Янв. 26, 2022

Язык: Английский

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Design, synthesis, herbicidal activity, in vivo enzyme activity evaluation and molecular docking study of acylthiourea derivatives as novel acetohydroxyacid synthase inhibitor

Journal of Molecular Structure, Год журнала: 2021, Номер 1241, С. 130627 - 130627

Опубликована: Май 9, 2021

Язык: Английский

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A novel, swift, and effective green synthesis of morpholino-pyridine analogues in microwave irradiation conditions

Results in Chemistry, Год журнала: 2022, Номер 5, С. 100692 - 100692

Опубликована: Ноя. 28, 2022

We report a facile, efficient, and environmentally benign approach for preparing morpholino-linked 1,4-dihydropyridine derivatives. The four-component fusion of morpholin-4-amine, diethyl acetylene dicarboxylate, malononitrile, chosen substituted benzaldehydes occurred under microwave irradiation mild conditions in the presence potassium carbonate as catalyst. This protocol offers remarkable benefits such excellent yields (92–98 %), easy handling, simple workup, economy, cleaner reaction profile, green conditions, shorter time (≤10 min), avoiding column chromatography purification.

Язык: Английский

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Microwave accelerated green access to functionalized pyrazolo[5,1-b]quinazoline-3-carboxylate scaffold and their pharmacological screening

Journal of Molecular Structure, Год журнала: 2024, Номер 1310, С. 138295 - 138295

Опубликована: Апрель 9, 2024

Язык: Английский

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A swift, facile and multicomponent synthesis of 4H-pyran-3-carbonitrile analogues via grinding process under solvent-free conditions

Chemical Data Collections, Год журнала: 2022, Номер 38, С. 100836 - 100836

Опубликована: Янв. 22, 2022

Язык: Английский

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Green Solvents: Application in Organic Synthesis

Green Chemistry, Год журнала: 2022, Номер unknown, С. 79 - 112

Опубликована: Янв. 1, 2022

Solvents play very important role in a chemical reaction by providing medium to solubilize the reacting components, reagents and also facilitate mass heat transfer processes. It affects kinetics stability of various species intermediates.

Язык: Английский

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An efficient synthesis of drug-like small molecules library based on 2-(substituted benzylthio)-4,6-dichloropyrimidin-5-amines

Chemical Data Collections, Год журнала: 2021, Номер 33, С. 100704 - 100704

Опубликована: Апрель 24, 2021

Язык: Английский

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