Food Chemistry,
Год журнала:
2023,
Номер
433, С. 137389 - 137389
Опубликована: Сен. 3, 2023
A
new
type
of
durian-shaped
Fe3O4@Au@Ag@Au
(DFAAA)
multilayer
core-shell
composite
was
prepared
as
an
efficient
surface-enhanced
Raman
scattering
(SERS)
substrate.
The
optimization
process
and
SERS
enhancement
mechanism
the
substrate
were
further
explained
with
finite-difference
time-domain
simulation.
dense
uniform
spiny
array
on
DFAAA
surface
had
abundant
"hot
spots",
greatly
improving
sensitivity,
uniformity
reproducibility,
a
factor
3.01
×
107
storage-life
30
d.
"flow
magnetic
detection
method"
proposed
to
realize
rapid
flexible
pesticide
residues
different
foods
including
fish
apple.
limit
malachite
green
thiram
apple
surfaces
0.13
0.18
ng/cm2,
respectively.
With
its
high
performance
good
magnetic,
possessed
great
application
prospects
facile
for
non-destructive
trace
foods.
Advanced Materials,
Год журнала:
2023,
Номер
36(10)
Опубликована: Фев. 25, 2023
Nanomaterials
with
more
than
one
enzyme-like
activity
are
termed
multienzymic
nanozymes,
and
they
have
received
increasing
attention
in
recent
years
hold
huge
potential
to
be
applied
diverse
fields,
especially
for
biosensing
therapeutics.
Compared
single
nanozymes
offer
various
unique
advantages,
including
synergistic
effects,
cascaded
reactions,
environmentally
responsive
selectivity.
Nevertheless,
along
these
merits,
the
catalytic
mechanism
rational
design
of
complicated
elusive
as
compared
single-enzymic
nanozymes.
In
this
review,
classification
scheme
based
on
numbers/types
activities,
internal
external
factors
regulating
multienzymatic
chemical,
biomimetic,
computer-aided
strategies,
progress
applications
attributed
advantages
multicatalytic
activities
systematically
discussed.
Finally,
current
challenges
future
perspectives
regarding
development
application
suggested.
This
review
aims
deepen
understanding
inspire
research
a
greater
extent.
Talanta,
Год журнала:
2022,
Номер
252, С. 123773 - 123773
Опубликована: Авг. 6, 2022
Aflatoxin
B1
(AFB1)
contamination
in
food
threatens
global
safety,
and
rapid
quantitative
detection
of
AFB1
remains
a
challenge.
Herein,
novel
fluorescence
biosensor
was
developed
for
based
on
CRISPR/Cas12a
MXenes.
Specifically,
the
well-designed
activator
locked
by
dual-AFB1
aptamers,
Cas12a
directly
linked
to
crRNA
form
inactivated
complexes,
MXenes
efficiently
adsorbed
FAM
fluorophore-modified
single-stranded
DNA
(ssDNA-FAM),
quenching
its
fluorescence.
In
presence
AFB1,
released
due
preferential
binding
aptamer
then
activated
trans-cleavage
activity
indiscriminately
cleave
ssDNA
MXenes,
leading
recovery
signal.
The
fluorescent
had
wide
range
from
0.001
80
ng
mL-1,
limit
0.92
pg
ability
detect
within
min.
More
importantly,
platform
demonstrates
excellent
performance
real
peanut
samples.
Food Hydrocolloids,
Год журнала:
2022,
Номер
135, С. 108138 - 108138
Опубликована: Сен. 15, 2022
The
growing
concerns
about
microbial
food
safety
and
environmental
contamination
call
for
sustainable
active
packaging
materials
practices
with
high
performance.
This
contribution
proposed
a
biocatalytic
spraying
coating
fruit
preservation
using
carboxymethyl
cellulose
nanofibers
grafting
enzyme-like
metal-organic
frameworks
([email
protected])
banana
mango
as
model
fruits.
well-characterized
biohybrid
were
verified
to
simultaneously
mimic
good
oxidase-like
apyrase-like
activities,
enabling
effective
sterilization
against
three
typical
foodborne
pathogens,
i.e.
Escherichia
coli
O157:
H7,
Staphylococcus
aureus,
methicillin-resistant
reaching
killing
rates
90.46%.
biocidal
•O2−
generation
adenosine
triphosphate
depletion
the
possible
mechanisms
causing
nonspecific
bacteria
death.
Such
antibacterial
performance,
well
additional
protective
properties
of
[email
protected],
facilitated
quality
during
12-day
storage
bananas
mangos
by
spray
biomimetic
protected]
It
is
expected
that
this
work
walks
out
first
step
nanozyme
toward
engineering
fields
food,
agriculture,
biomedicine.
Advanced Materials,
Год журнала:
2023,
Номер
36(2)
Опубликована: Авг. 1, 2023
Chronic
wounds
are
characterized
by
delayed
and
dysregulated
healing
processes.
As
such,
they
have
emerged
as
an
increasingly
significant
threat.
The
associated
morbidity
socioeconomic
toll
clinically
financially
challenging,
necessitating
novel
approaches
in
the
management
of
chronic
wounds.
Metal-organic
frameworks
(MOFs)
innovative
type
porous
coordination
polymers,
with
low
toxicity
high
eco-friendliness.
Documented
anti-bacterial
effects
pro-angiogenic
activity
predestine
these
nanomaterials
promising
systems
for
treatment
In
this
context,
therapeutic
applicability
efficacy
MOFs
remain
to
be
elucidated.
It
is,
therefore,
reviewed
structural-functional
properties
their
composite
materials
discusses
how
multifunctionality
customizability
can
leveraged
a
clinical
therapy
Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy,
Год журнала:
2022,
Номер
284, С. 121817 - 121817
Опубликована: Авг. 30, 2022
With
the
growing
popularity
of
non-destructive
technique,
surface-enhanced
Raman
spectroscopy
(SERS)
demands
a
highly
sensitive
and
reproducible
plasmonic
nanoparticles
substrate.
In
this
study,
novel
bimetallic
core-shell
(Au@Ag@mSiO2NP)
substrate
consisting
gold
core,
silver
shell,
mesoporous
silica
coating
was
synthesized.
The
structure
created
by
employing
template
molecules
such
as
surfactant
their
subsequent
removal
allowing
selective
screening
based
on
size
analyte
molecules.
Results
showed
that
could
selectively
enhance
small
preventing
large
macromolecules
to
reach
exciting
zone
achieving
detection
chloramphenicol
in
milk
samples
with
limit
6.68
×
10-8
M.
Moreover,
provided
additional
stability
Au@Ag
nanoparticles,
leading
reusability
Thus,
work
offered
simple
smart
Au@Ag@mSiO2NP
for
effective
SERS
analytes.
Chemical Engineering Journal,
Год журнала:
2022,
Номер
452, С. 139078 - 139078
Опубликована: Сен. 8, 2022
Being
a
unique
biocatalyst
to
hydrolyse
structural
polysaccharides
on
the
cell
wall
of
bacteria,
lysozyme
can
slow
down
bacterial
resistance
caused
by
antibiotic
overdose
treatments,
however,
efficient
activation
activities
under
pathogenic
microenvironments
remains
challenging.
Herein,
bio-interface
engineering
strategy
was
proposed
for
remote
modulation
thermoresistant
upon
rationally
designed
photothermal
nanoplatforms.
For
this,
Ti3C2TX
MXene
nanosheets
were
functionalized
polydopamine
(PDA)
surface
chemistry
enhance
effects
and
performance
durability,
during
which
biomacromolecules
immobilized
at
such
two-dimensional
hybrid
interface
via
intermolecular
electrostatic
affinity.
The
integrated
nanoplatform
(denoted
as
M@P@Lyso),
with
an
optimal
high
light-to-heat
conversion
efficiency
46.88%,
realized
not
only
precision
control
local
heat
but
also
photo-responsive
up-regulation
bio-catalysis
laden
lysozyme.
As
result,
in
vitro
vivo
antibacterial
experiments
revealed
that
M@P@Lyso
could
effectively
inhibit
proliferation
methicillin-resistant
Staphylococcus
aureus
accelerated
wound
disinfection
mice
negligible
biological
toxicities.
outstanding
attributed
photo-enhanced
activity,
assisted
death
mild
hyperthermia
physical
destruction
derived
from
M@PDA.
This
work
exemplified
solution
threats
stimuli-responsive
enzymatic
With
the
advantages
of
diverse
structures,
tunable
enzymatic
activity,
and
high
stability,
nanozymes
are
widely
used
in
medicine,
chemistry,
food,
environment,
other
fields.
As
an
alternative
to
traditional
antibiotics,
attract
more
attention
from
scientific
researchers
recent
years.
Developing
nanozymes-based
antibacterial
materials
opens
up
a
new
avenue
for
bacterial
disinfection
sterilization.
In
this
review,
classification
their
mechanisms
discussed.
The
surface
composition
critical
efficacy,
which
can
be
tailored
enhance
both
binding
activity.
On
one
hand,
modification
enables
targeting
bacteria
that
improves
performance
including
biochemical
recognition,
charge,
topography.
modulated
achieve
enhanced
single
nanozyme-mediated
synergistic
multiple
nanozymes-mediated
cascade
catalytic
applications.
addition,
current
challenges
future
prospects
tailoring
applications
This
review
provide
insights
into
design
treatments.
Nature Communications,
Год журнала:
2024,
Номер
15(1)
Опубликована: Фев. 3, 2024
Abstract
The
reaction
system
of
hydrogen
peroxide
(H
2
O
)
catalyzed
by
nanozyme
has
a
broad
prospect
in
antibacterial
treatment.
However,
the
complex
catalytic
activities
nanozymes
lead
to
multiple
pathways
reacting
parallel,
causing
uncertain
results.
New
approach
effectively
regulate
is
urgent
need.
Herein,
Cu
single
site
modified
on
nanoceria
with
various
activities,
such
as
peroxidase-like
activity
(POD)
and
hydroxyl
radical
antioxidant
capacity
(HORAC).
Benefiting
from
interaction
between
coordinated
CeO
substrate,
POD
enhanced
while
HORAC
inhibited,
which
further
confirmed
density
functional
theory
(DFT)
calculations.
Cu-CeO
+
H
shows
good
properties
both
vitro
vivo.
In
this
work,
strategy
based
metal
carrier
provides
general
clue
for
optimizing
nanozymes.
Food Chemistry,
Год журнала:
2024,
Номер
448, С. 139078 - 139078
Опубликована: Март 22, 2024
A
fluorescent
sensor
array
(FSA)
combined
with
deep
learning
(DL)
techniques
was
developed
for
meat
freshness
real-time
monitoring
from
development
to
deployment.
The
made
up
of
copper
metal
nanoclusters
(CuNCs)
and
dyes,
having
a
good
ability
in
the
quantitative
qualitative
detection
ammonia,
dimethylamine,
trimethylamine
gases
low
limit
(as
as
131.56
ppb)
range
5
∼
1000
ppm
visually
various
meats
stored
at
4
°C.
Moreover,
SqueezeNet
applied
automatically
identify
fresh
level
based
on
FSA
images
high
accuracy
(98.17
%)
further
deployed
production
environments
such
personal
computers,
mobile
devices,
websites
by
using
open
neural
network
exchange
(ONNX)
technique.
entire
recognition
process
only
takes
7
s.
Furthermore,
gradient-weighted
class
activation
mapping
(Grad-CAM)
uniform
manifold
approximation
projection
(UMAP)
explanatory
algorithms
were
used
improve
interpretability
transparency
SqueezeNet.
Thus,
this
study
shows
new
idea
assisted
DL
intelligent