BMC Complementary Medicine and Therapies,
Год журнала:
2024,
Номер
24(1)
Опубликована: Апрель 8, 2024
Gels
loaded
with
nanocarriers
offer
interesting
ways
to
create
novel
therapeutic
approaches
by
fusing
the
benefits
of
gel
and
nanotechnology.
Clinical
studies
indicate
that
lavender
oil
(Lav-O)
has
a
positive
impact
on
accelerating
wound
healing
properly
based
its
antimicrobial
anti-inflammatory
effects.
Initially
Lav-O
Solid
Lipid
Nanoparticles
(Lav-SLN)
were
prepared
incorporating
cholesterol
lecithin
natural
lipids
SLNs
characterized.
Next,
3%
SLN
containing
topical
(Lav-SLN-G)
was
formulated
using
Carbopol
940.
Both
Lav-SLN
Lav-SLN-G
assessed
in
terms
antibacterial
effects
against
S.
aureus.
Lav-SLNs
revealed
particle
size
19.24
nm,
zeta
potential
-21.6
mv
EE%
75.46%.
Formulated
presented
an
acceptable
pH
texture
properties.
Minimum
Inhibitory/Bactericidal
Concentration
(MIC/MBC)
aureus
for
LAv-O,
0.12
0.24
mgml
International Journal of Molecular Sciences,
Год журнала:
2023,
Номер
24(11), С. 9375 - 9375
Опубликована: Май 27, 2023
The
rapid
development
of
antimicrobial
resistance
due
to
broad
antibiotic
utilisation
in
the
healthcare
and
food
industries
non-availability
novel
antibiotics
represents
one
most
critical
public
health
issues
worldwide.
Current
advances
nanotechnology
allow
new
materials
address
drug-resistant
bacterial
infections
specific,
focused,
biologically
safe
ways.
unique
physicochemical
properties,
biocompatibility,
wide
range
adaptability
nanomaterials
that
exhibit
photothermal
capability
can
be
employed
develop
next
generation
photothermally
induced
controllable
hyperthermia
as
antibacterial
nanoplatforms.
Here,
we
review
current
state
art
different
functional
classes
strategies
optimise
efficiency.
recent
achievements
trends
developing
active
nanostructures,
including
plasmonic
metals,
semiconductors,
carbon-based
organic
polymers,
mechanisms
action,
anti-multidrug-resistant
bacteria
biofilm
removal,
will
discussed.
Insights
into
effect
various
factors
influencing
performance,
emphasising
structure-performance
relationship,
are
We
examine
agents'
functionalisation
for
specific
bacteria,
effects
near-infrared
light
irradiation
spectrum,
multimodal
synergistic-based
therapies
minimise
side
maintain
low
costs.
relevant
applications
presented,
such
antibiofilm
formation,
penetration
or
ablation,
nanomaterial-based
infected
wound
therapy.
Practical
employing
agents,
alone
synergistic
combination
with
other
nanomaterials,
considered.
Existing
challenges
limitations
therapy
future
perspectives
presented
from
structural,
functional,
safety,
clinical
potential
points
view.
Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy,
Год журнала:
2023,
Номер
294, С. 122548 - 122548
Опубликована: Фев. 24, 2023
Surface-enhanced
Raman
spectroscopy
(SERS)
technology
has
been
revived
and
developed
with
the
introduction
of
metal-organic
frameworks
(MOFs),
while
more
valuable
properties
MOFs
for
SERS
substrates
remain
largely
unexplored.
This
work
constructed
a
new
substrate
Fe3O4@UiO-66(Zr)@Ag
nanoparticles
(FUAs)
excellent
detection
sensitivity,
uniformity,
reproducibility
stability,
exhibiting
high
enhancement
factor
(5.62
×
106),
low
limit
(LOD,
2.11
10-11
M)
RSD
(12.41
%)
4-NBT,
maintaining
81
%
activity
within
60
days.
The
FUAs
took
full
advantage
strong
affinity
UiO-66(Zr)
organophosphorus
pesticides
(OPs)
to
realize
trace
OPs
detection.
LODs
phoxim,
triazophos
methyl
parathion
in
apple
juice
were
0.041,
0.021
0.0031
mg/L,
respectively,
good
linearities
ranging
from
0.02
or
0.1-50
meeting
requirements
food
control
standards,
indicating
that
potentials
prospects
detecting
foods.
Abstract
This
review
highlights
recent
advancements
in
the
synthesis,
processing,
properties,
and
applications
of
2D‐material
integrated
hydrogels,
with
a
focus
on
their
performance
bone‐related
applications.
Various
synthesis
methods
types
2D
nanomaterials,
including
graphene,
graphene
oxide,
transition
metal
dichalcogenides,
black
phosphorus,
MXene
are
discussed,
along
strategies
for
incorporation
into
hydrogel
matrices.
These
composite
hydrogels
exhibit
tunable
mechanical
high
surface
area,
strong
near‐infrared
(NIR)
photon
absorption
controlled
release
capabilities,
making
them
suitable
range
regeneration
therapeutic
In
cancer
therapy,
2D‐material‐based
show
promise
photothermal
photodynamic
therapies,
drug
delivery
(chemotherapy).
The
properties
these
materials
enable
selective
tumor
ablation
upon
NIR
irradiation,
while
drug‐loading
capacity
facilitates
targeted
chemotherapeutic
agents.
Additionally,
2D‐materials
‐infused
potent
antibacterial
activity,
effective
against
multidrug‐resistant
infections
disruption
biofilm
generated
implant
surface.
Moreover,
synergistic
therapy
approach
combines
multiple
treatment
modalities
such
as
photothermal,
chemo,
immunotherapy
to
enhance
outcomes.
bio‐imaging,
serve
versatile
contrast
agents
imaging
probes,
enabling
real‐time
monitoring
during
imaging.
Furthermore,
bone
regeneration,
most
incorporated
promote
osteogenesis
tissue
offering
potential
solutions
defects
repair.
Overall,
integration
presents
promising
platform
developing
multifunctional
theragenerative
biomaterials.
