ACS Applied Nano Materials,
Год журнала:
2024,
Номер
7(9), С. 10998 - 11007
Опубликована: Апрель 29, 2024
Infections
caused
by
bacteria
pose
a
serious
threat
to
public
health,
and
there
is
need
for
numerous
innovative,
antibiotic-free
antimicrobial
medicines.
Herein,
we
describe
the
synthesis
of
CuS/Co-ferrocene-MOF
(CuS/Co-Fc-MOF)
nanocomposites,
formed
coupling
CuS
nanoparticles
(NPs)
two-dimensional
(2D)
Co-Fc-MOF
nanosheets,
that
constitutes
an
platform
capable
near-infrared
(NIR)
photothermal
promotion
chemodynamic
antibacterial.
2D
CuS/Co-Fc-MOF
nanocomposites
consist
nanosheets
with
dimensions
approximately
100–200
nm
thicknesses
13.1–15.6
nm,
where
NPs,
size
about
8
are
excellently
dispersed
on
surface
nanosheets.
The
diverse
valence
states
cobalt
iron
in
enable
them
undergo
Fenton-like
reactions
H2O2,
thus
generating
highly
oxidizing
·OH
therapy
(CDT).
utilization
local
plasmonic
resonance
effect
NPs
enables
enhancement
CDT
activity
under
laser
irradiation.
More
importantly,
can
achieve
rapid
(15
min)
NIR
laser-assisted
killing
both
S.
aureus
E.
coli
bacterial
infection
microenvironment
compared
Therefore,
be
employed
as
promising
nanoagent
promote
photothermally
augmented
antibacterial
therapy.
Journal of Nanobiotechnology,
Год журнала:
2024,
Номер
22(1)
Опубликована: Апрель 26, 2024
Carbon
dots
(CDs)
are
novel
carbon-based
nanomaterials
that
have
been
used
as
photosensitizer-mediated
photodynamic
therapy
(PDT)
in
recent
years
due
to
their
good
photosensitizing
activity.
Photosensitizers
(PSs)
main
components
of
PDT
can
produce
large
amounts
reactive
oxygen
species
(ROS)
when
stimulated
by
light
source,
which
the
advantages
low
drug
resistance
and
high
therapeutic
efficiency.
CDs
generate
ROS
efficiently
under
irradiation
therefore
extensively
studied
disease
local
phototherapy.
In
tumor
therapy,
be
PSs
or
PS
carriers
participate
play
an
extremely
important
role.
bacterial
infectious
diseases,
exhibit
bactericidal
activity
effective
disrupting
cell
membranes
leading
death
upon
photoactivation.
We
focus
on
advances
cancer
bacteria
with
CDs,
also
briefly
summarize
mechanisms
requirements
for
cancer,
other
diseases.
discuss
role
combination
potential
future
applications
against
pathogens.
Advanced Functional Materials,
Год журнала:
2024,
Номер
34(38)
Опубликована: Апрель 30, 2024
Abstract
Microbial
infections
pose
a
significant
threat
to
public
health,
exacerbated
by
the
escalating
issue
of
antibiotic
resistance
resulting
from
their
overuse.
Chiral
carbon
dots
(CDs)
not
only
inherit
antibacterial
properties
CDs
but
also
demonstrate
highly
selective
chiral
bactericidal
activity.
This
study
focuses
on
development
synthesized
D‐
and
L‐cysteine,
selectively
identify
synergistically
eradicate
Gram‐positive
bacteria
fungi.
exhibit
high
efficacy
in
staining
fungi
while
demonstrating
minimal
no
fluorescence
with
Gram‐negative
bacteria,
attributable
variances
membrane
structures
these
pathogens.
D‐CDs
stronger
signals
greater
against
compared
L‐CDs.
Under
dual
light
irradiation,
bolster
activity
through
triple‐modal
mechanism,
involving
disruption
absence
light,
singlet
oxygen
generation
during
photodynamic
therapy,
elevated
temperature
photothermal
treatment.
Animal
studies
additionally
showcase
that
notably
enhanced
healing
wounds
infected
S.
aureus
under
laser
exposure.
investigation
underscores
chiral‐specific
imaging
potentials
D‐CDs,
paving
way
for
advancement
nanomaterials
bacterial
diagnostics
therapy.
Nano Letters,
Год журнала:
2024,
Номер
24(13), С. 4044 - 4053
Опубликована: Март 22, 2024
Fungal
keratitis
(FK)
is
an
infectious
eye
disease
that
poses
a
significant
risk
of
blindness.
However,
the
effectiveness
conventional
antifungal
drugs
limited
due
to
intrinsic
ocular
barrier
impedes
drug
absorption.
There
urgent
need
develop
new
therapeutic
strategies
effectively
combat
FK.
Herein,
we
synthesized
ultrasmall
positively
charged
carbon
dot
using
simple
stage-melting
method.
The
can
penetrate
corneal
by
opening
tight
junctions,
allowing
them
reach
lesion
site
and
kill
fungi.
results
both
in
vitro
vivo
demonstrated
it
exhibited
good
biocompatibility
activity,
significantly
improving
effect
mouse
model
Therefore,
this
biophilic
size
positive
dot,
characterized
its
ability
properties,
may
offer
valuable
insights
into
design
effective
nanomedicines.
Journal of Materials Research and Technology,
Год журнала:
2023,
Номер
28, С. 3865 - 3881
Опубликована: Дек. 27, 2023
Using
l-histidine
and
cerium
nitrate
hexahydrate
as
raw
materials,
a
green
effective
carbon
dots
(Ce,N-CDs)
was
prepared
using
hydrothermal
synthesis
their
structures
were
confirmed
by
professional
equipment.
The
anti-bacterial
anti-corrosive
behaviors
of
Ce,N-CDs
systemically
evaluated
plate
counting
method
electrochemical
method,
respectively.
By
analysis,
the
showed
high
bacterial
inhibition
efficiency
for
Escherichia
coli
(E.
coli),
which
up
to
94.27
%.
Compared
with
N-doping
(N-CDs),
exhibited
an
excellent
ability.
At
200
mg/l,
its
corrosion
(IE)
Cu
higher
than
90
%
at
different
environment
temperatures
(308,
318,
323
K),
rate
(WL)
sharply
reduced.
This
attributed
presence
N–Cu
bond
formation
Ce-containing
passive
film.
film
could
block
erosion
aggressive
ions.
facilitated
chemical
adsorption
on
surface,
quantum
chemistry
(QC)
molecular
dynamics
(MD).
Nano Letters,
Год журнала:
2023,
Номер
23(24), С. 11755 - 11762
Опубликована: Дек. 13, 2023
The
issues
of
fruit
waste
and
safety
resulting
from
rot
have
spurred
a
demand
for
improved
packaging
systems.
Herein,
we
present
highly
antibacterial
antioxidative
carbon
nanodot/silk
fibroin
(CD/SF)
films
preservation.
are
composed
CDs
SF
together
with
small
amount
glycerol
via
hydrogen
bonding,
exhibiting
outstanding
biosafety,
transparency,
stretchability.
effectively
integrate
key
functionalities
(atmosphere
control,
resistance
to
food-borne
pathogens,
antioxidation
properties)
can
be
manufactured
in
large
sizes
(about
20
×
30
cm),
boasting
transmission
rate
13
183
cm3/m2·day
oxygen
2860
g/m2·day
water
vapor,
favoring
the
preservation
fresh
fruits.
A
convenient
dip-coating
method
enables
situ
fabrication
thickness
approximately
14
μm
directly
on
fruits'
surface
providing
comprehensive
protection.
Importantly,
washable
biodegradable.
This
work
presents
promising
technology
produce
multifunctional
eco-friendly
Carbon
dots
(CDs),
a
class
of
carbon-based
nanomaterials
with
dimensions
less
than
10
nm,
have
attracted
significant
interest
since
their
discovery.
They
possess
numerous
excellent
properties,
such
as
tunability
photoluminescence,
environmental
friendliness,
low
cost,
and
multifunctional
applications.
Recently,
large
number
reviews
emerged
that
provide
overviews
synthesis,
applications,
composite
functionalization.
The
application
CDs
in
the
field
optoelectronics
has
also
seen
unprecedented
development
due
to
optical
but
them
this
are
relatively
rare.
With
idea
deepening
broadening
understanding
applications
optoelectronics,
review
for
first
time
provides
detailed
summary
luminescent
solar
concentrators
(LSCs),
light-emitting
diodes
(LEDs),
cells,
photodetectors.
In
addition,
definition,
categories,
synthesis
methods
briefly
introduced.
It
is
hoped
can
bring
scholars
more
deeper
optoelectronic
further
promote
practical
CDs.
