Chemical Engineering Journal, Год журнала: 2024, Номер 498, С. 155575 - 155575
Опубликована: Сен. 7, 2024
Язык: Английский
Chemical Engineering Journal, Год журнала: 2024, Номер 498, С. 155575 - 155575
Опубликована: Сен. 7, 2024
Язык: Английский
Chemical Engineering Science, Год журнала: 2024, Номер 300, С. 120620 - 120620
Опубликована: Авг. 23, 2024
Язык: Английский
Процитировано
6Advanced Functional Materials, Год журнала: 2024, Номер unknown
Опубликована: Окт. 25, 2024
Abstract Polyphenol hydrogels have found widespread application in wound healing, bone repair, drug delivery, and biosensors due to their robust wet adhesion, high ductility, excellent self‐healing ability. However, these often exhibit low intrinsic cohesion, which limits overall adhesive strength. Enhancing cohesion is critical for improving both the adhesion mechanical properties of hydrogels, thereby expanding utility biomedical fields. This review begins by exploring strategies enhance polyphenol hydrogel adhesives, detailing modifications that act individually or synergistically. The importance temporally regulating emphasized accommodate various applications environmental conditions. Finally, this paper discusses remaining challenges regulation outlines prospects future research. It hoped comprehensive will provide new insights into development advanced polyphenolic adhesives contribute design “smart adhesives” increasingly complex needs applications.
Язык: Английский
Процитировано
6Small, Год журнала: 2023, Номер 20(3)
Опубликована: Сен. 8, 2023
Abstract Diabetic chronic wounds pose significant clinical challenges due to their characteristic features of impaired extracellular matrix (ECM) function, diminished angiogenesis, inflammation, and increased susceptibility infection. To tackle these provide a comprehensive therapeutic approach for diabetic wounds, the first coaxial electrospun nanocomposite membrane is developed that incorporates multifunctional copper peroxide nanoparticles ( n ‐CuO 2 ). The membrane's nanofiber possesses unique “core/sheath” structure consisting +PVP (Polyvinylpyrrolidone)/PCL (Polycaprolactone) composite sheath PCL core. When exposed wound's moist environment, PVP within gradually disintegrates, releasing embedded . Under weakly acidic microenvironment (typically infected wounds), decomposes release H O Cu 2+ ions subsequently produce ·OH through chemodynamic reactions. This enables anti‐bacterial activity mediated by reactive oxygen species (ROS), suppressing inflammation while enhancing angiogenesis. At same time, dissolution unveils nano‐grooved surface patterns on nanofibers, providing desirable cell‐guiding function required accelerated skin regeneration. Through meticulous material selection design, this study pioneers development functional nanocomposites multi‐modal wound therapy, which holds great promise in guiding path healing wounds.
Язык: Английский
Процитировано
16Chemical Engineering Journal, Год журнала: 2023, Номер 476, С. 146642 - 146642
Опубликована: Окт. 14, 2023
Язык: Английский
Процитировано
14Chemical Engineering Journal, Год журнала: 2024, Номер 498, С. 155575 - 155575
Опубликована: Сен. 7, 2024
Язык: Английский
Процитировано
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