Asian Journal of Organic Chemistry,
Год журнала:
2021,
Номер
11(2)
Опубликована: Дек. 15, 2021
Abstract
An
efficient
and
environmentally‐friendly
synthesis
of
aryl
ketones
through
the
electrochemical
catalytic
hydrocarbonylation
arylacetylene
is
demonstrated.
The
reaction
conditions
are
mild
without
transition
metal
catalysts,
extra
oxidants,
or
strong
acids
involved.
By
using
Selectfluor
as
additive,
this
transformation
exhibits
good
functional‐group
tolerance.
ketone
product
obtained
with
up
to
90%
isolated
yield
in
mixed
electrolytes
acetonitrile
water.
This
method
may
open
a
new
window
for
green
from
arylacetylenes.
Angewandte Chemie International Edition,
Год журнала:
2023,
Номер
62(26)
Опубликована: Апрель 22, 2023
Abstract
The
selective
electrochemical
synthesis
of
1
H
‐indazoles
and
their
N
‐oxides
the
subsequent
C−H
functionalization
‐indazole
are
described.
outcomes
were
determined
by
nature
cathode
material.
When
a
reticulated
vitreous
carbon
was
used,
wide
range
selectively
synthesized,
electrosynthesis
products
deoxygenated
to
N‐heteroaromatics,
owing
cathodic
cleavage
N−O
bond
via
paired
electrolysis,
when
Zn
used.
scope
this
protocol
is
broad,
as
both
electron‐rich
electron‐poor
substrates
tolerated.
potency
strategy
demonstrated
through
late‐stage
various
bioactive
molecules,
making
reaction
attractive
for
derivatives
pharmaceutical
research
development.
Detailed
mechanistic
investigations
involving
electron
paramagnetic
resonance
spectroscopy
cyclic
voltammetry
suggested
radical
pathway
featuring
iminoxyl
radicals.
Owing
rich
reactivity
‐oxides,
diverse
reactions
performed.
We
synthetic
utility
synthesizing
molecules
lificiguat
YD
(3);
key
intermediates
bendazac,
benzydamine,
norepinephrine/serotonin
reuptake
inhibitors,
SAM‐531,
gamendazole
analogues;
precursor
organic
light‐emitting
diodes.
Green Chemistry,
Год журнала:
2022,
Номер
24(11), С. 4557 - 4565
Опубликована: Янв. 1, 2022
The
need
for
an
operationally
straightforward
application
of
radical
chemistry
has
led
researchers
to
explore
practical
strategies
obtain
and
trap
radicals.
European Journal of Organic Chemistry,
Год журнала:
2022,
Номер
2022(39)
Опубликована: Окт. 18, 2022
Abstract
In
this
review,
we
highlighted
the
main
achievements
in
field
of
electrocatalytic
generation
acyl
radicals
and
their
applications.
These
electrochemical
strategies
were
introduced
with
an
emphasis
on
substrate
scope,
reaction
limitation
underlying
mechanism.
The
related
reactions
categorized
according
to
pathways
radical
generation,
including
outer‐sphere
electron
transfer
(ET),
inner‐sphere
ET,
hydrogen
atom
(HAT)
processes.
Green Chemistry,
Год журнала:
2022,
Номер
24(19), С. 7388 - 7394
Опубликована: Янв. 1, 2022
An
environmentally
friendly
electrochemical
process
for
the
direct
trifluoromethylation
of
2-pyridones
with
a
broad
substrate
scope
has
been
developed.
Science China Chemistry,
Год журнала:
2022,
Номер
unknown
Опубликована: Дек. 12, 2022
Abstract
During
the
past
few
years,
electrochemical
oxidative
reactions
through
radical
intermediates
have
emerged
as
an
environmentally-benign,
powerful
platform
for
facile
formation
of
C–E
(E
=
C,
N,
S,
Se,
O
and
Hal)
bonds
single-electron-transfer
(SET)
processes
at
electrodes.
Functionalized
unsaturated
molecules
unusual
structural
motifs
can,
instance,
be
directly
constructed
under
exceedingly
mild
reaction
conditions
initial
attack
onto
alkynes.
This
minireview
highlights
recent
advances
in
electrooxidation
until
June
2022,
with
a
particular
focus
on
additions
Beilstein Journal of Organic Chemistry,
Год журнала:
2024,
Номер
20, С. 1988 - 2004
Опубликована: Авг. 14, 2024
Hydrazones
are
important
structural
motifs
in
organic
synthesis,
providing
a
useful
molecular
platform
for
the
construction
of
valuable
compounds.
Electrooxidative
transformations
hydrazones
constitute
an
attractive
opportunity
to
take
advantage
versatility
these
reagents.
By
directly
harnessing
electrical
current
perform
oxidative
process,
large
panel
molecules
can
be
accessed
from
readily
available
under
mild,
safe
and
oxidant-free
reaction
conditions.
This
review
presents
comprehensive
overview
electrosynthetic
hydrazones.
It
includes
azacycles,
C(sp
