Cells, Год журнала: 2024, Номер 13(11), С. 958 - 958
Опубликована: Июнь 1, 2024
Autophagy is a globally conserved cellular activity that plays critical role in maintaining homeostasis through the breakdown and recycling of constituents. In recent years, there has been much emphasis given to its complex cancer stem cells (CSCs) cell treatment. This study examines molecular processes support autophagy how it regulated context CSCs Although dual management CSCs, affecting their removal as well maintenance, intricate interaction between several signaling channels control survival death part mechanism not elucidated. Given have development, progression, resistance treatment tumors, imperative comprehend biological activities. are important for biology because they also show tissue regeneration model helps with organoid regeneration. other words, manipulation viable therapeutic approach therapy. Both synthetic natural substances target pathways demonstrated promise improving cell-based therapies eliminating CSCs. Nevertheless, difficulties associated limitations CSC regulation, including mechanisms off-target effects. Thus, regulation offers versatile strategy focusing on enhancing results Therefore, understanding interactions would be essential creating treatments work both regenerative medicine
Язык: Английский