The
pharmaceutical
manufacturing
sector
is
going
through
a
significant
shift
as
it
adopts
sophisticated
analytics
and
predictive
maintenance
drivers
of
efficiency
innovation.This
research
investigates
how
regulatory
changes,
technical
developments,
sustainability
requirements
are
converging
to
shape
the
future
production.Manufacturers
empowered
by
maintenance,
transition
from
reactive
proactive
methods,
reduce
downtime,
maximize
resources,
uphold
compliance.Regulatory
organizations
becoming
more
helpful,
offering
precise
rules
for
smooth
implementation.With
Industry
4.0
technologies
providing
real-time
insights
operational
quality
control,
data-driven
excellence
emerges
persistent
quest.Digital
twins
revolutionize
simulation
monitoring,
reducing
physical
testing
hastening
product
development.Collaborations
with
IT
companies
have
hastened
uptake
innovations.Comprehending
futuristic
breakdown
anticipating
health
line
manufacturing,
model
called
PharMTrans
has
been
built
in
this
study,
employing
bi-linear
outcome
technique
four
analysis
phases.A
data-rich,
proactive,
sustainable
approach
will
guide
future.The
industry
well-positioned
design
where
efficiency,
quality,
intersect,
ensuring
production
remains
foundation
global
well-being.This
accomplished
maintenance.
Biosensors,
Год журнала:
2025,
Номер
15(3), С. 191 - 191
Опубликована: Март 17, 2025
Cardiovascular
diseases
have
long
been
a
major
challenge
to
human
health,
and
the
treatment
differences
caused
by
individual
variability
remain
unresolved.
In
recent
years,
personalized
cardiovascular
drug
therapy
has
attracted
widespread
attention.
This
paper
reviews
strategies
for
achieving
through
traditional
dynamic
monitoring
multidimensional
data
integration
analysis.
It
focuses
on
key
technologies
monitoring,
based
differences,
By
systematically
reviewing
relevant
literature,
main
challenges
in
current
research
proposed
potential
directions
future
studies
were
summarized.
Sensing and Bio-Sensing Research,
Год журнала:
2024,
Номер
44, С. 100644 - 100644
Опубликована: Март 26, 2024
Nuts
are
a
well-known
cause
of
food
allergy
and,
once
this
has
been
diagnosed,
due
to
the
likelihood
cross-sensitization
multiple
tree
nut
allergens,
their
strict
avoidance
from
diet
is
advisable.
In
context,
we
present
electrochemical
bioplatforms
detect
traces
hazelnut
and
walnut
in
processed
foods
through
determination
respective
allergenic
proteins
Cor
9
Jug
r
1
fast
sensitive
assay.
First,
evaluation
single
both
was
performed
by
building
sandwich
immunoconjugates
on
surface
magnetic
microbeads
relying
specific
antibodies
unmodified
or
conjugated
horseradish
peroxidase.
Amperometric
transduction
made
upon
trapping
bioconjugates
disposable
carbon
electrodes,
using
hydroquinone/hydrogen
peroxide
system.
The
great
analytical
performance
achieved
with
individual
platforms
(detection
limits
0.12
0.56
ng
mL−1
for
9,
respectively),
led
us
dual
quantification
raw
dough
baked
cookies
incurred
ground
nuts.
developed
method
allowed
detecting
0.0025%
0.00002%
results
comparable
those
provided
ELISA
techniques.
feasibility
performing
allergens
run
demonstrated.
Talanta,
Год журнала:
2024,
Номер
277, С. 126350 - 126350
Опубликована: Июнь 2, 2024
This
work
reports
the
development
and
application
of
a
disposable
amperometric
sensor
built
on
magnetic
microcarriers
coupled
to
an
Express
PCR
strategy
amplify
specific
DNA
fragment
chloroplast
trnH-psbA.
The
procedure
involves
selective
capture
68-mer
synthetic
target
(or
unmodified
products)
through
sandwich
hybridization
with
RNA
probe-modified
streptavidin
MBs
signaling
probes,
labeled
using
antibodies
heteroduplexes
secondary
tagged
horseradish
peroxidase.
Amperometric
measurements
were
performed
screen-printed
electrodes
H
Current Opinion in Electrochemistry,
Год журнала:
2023,
Номер
41, С. 101359 - 101359
Опубликована: Июль 27, 2023
The
tremendous
advances
in
electrochemical
biosensing
that
have
occurred
recently,
highlighting
as
never
before
the
versatility
and
adaptability
of
resulting
biotools,
together
with
innovations
natural-inspired
bioreceptor
production,
electrode
substrate
fabrication,
miniaturizable
electronics,
materials
science,
digitization
artificial
intelligence
can
empower
changed
perception
what
we
seen
offer
us.
This
minireview
aims
to
give
a
brief
current
bird's
eye
view
most
recent
involving
design,
manufacturing,
characteristics
applications,
supported
by
references
broaden
deepen
concepts.
goal
is
convince
reader
bioanalysis
has
so
far
only
shown
us
small
part
its
wide
multifaceted
world
which
will
continue
be
privileged
witnesses
coming
years.
Characterization and Application of Nanomaterials,
Год журнала:
2024,
Номер
7(1), С. 4654 - 4654
Опубликована: Апрель 12, 2024
Recently,
carbon
nanocomposites
have
garnered
a
lot
of
curiosity
because
their
distinctive
characteristics
and
extensive
variety
possible
possibilities.
Among
all
these
applications,
the
development
sensors
with
electrochemical
properties
based
on
for
use
in
biomedicine
has
shown
as
an
area
potential.
These
are
suitable
assortment
biomedical
such
prescribing
medications,
disease
diagnostics,
biomarker
detection.
They
many
benefits,
including
outstanding
sensitivity,
selectivity,
low
limitations
This
comprehensive
review
aims
to
provide
in-depth
analysis
recent
advancements
nanocomposites-based
applications.
The
different
types
nanomaterials
used
sensor
fabrication,
synthesis
methods,
functionalization
techniques
employed
enhance
sensing
been
discussed.
Furthermore,
we
enumerate
numerous
biological
uses
nanocomposites,
among
them
employment
illness
diagnosis,
physiological
parameter
monitoring,
biomolecule
challenges
prospects
applications
also
Overall,
this
highlights
tremendous
potential
nanomaterial-based
revolutionizing
research
clinical
diagnostics.
