Advanced Analytics and Predictive Maintenance in Pharmaceutical Manufacturing DOI Open Access

Comfort Iyanda,

Kai Yang

IARJSET, Journal Year: 2023, Volume and Issue: 10(11)

Published: Oct. 30, 2023

The pharmaceutical manufacturing sector is going through a significant shift as it adopts sophisticated analytics and predictive maintenance drivers of efficiency innovation.This research investigates how regulatory changes, technical developments, sustainability requirements are converging to shape the future production.Manufacturers empowered by maintenance, transition from reactive proactive methods, reduce downtime, maximize resources, uphold compliance.Regulatory organizations becoming more helpful, offering precise rules for smooth implementation.With Industry 4.0 technologies providing real-time insights operational quality control, data-driven excellence emerges persistent quest.Digital twins revolutionize simulation monitoring, reducing physical testing hastening product development.Collaborations with IT companies have hastened uptake innovations.Comprehending futuristic breakdown anticipating health line manufacturing, model called PharMTrans has been built in this study, employing bi-linear outcome technique four analysis phases.A data-rich, proactive, sustainable approach will guide future.The industry well-positioned design where efficiency, quality, intersect, ensuring production remains foundation global well-being.This accomplished maintenance.

Language: Английский

Fabrication of Electrochemically Stable 3D V2O5/Nickel Foam Electrode with Enhanced Photoelectrochemical Activity for High-Performance Glucose Sensing DOI
Muhammad Hilal, Yasir Ali, Zhicheng Cai

et al.

Surfaces and Interfaces, Journal Year: 2025, Volume and Issue: unknown, P. 106097 - 106097

Published: Feb. 1, 2025

Language: Английский

Citations

0

Analysis of Personalized Cardiovascular Drug Therapy: From Monitoring Technologies to Data Integration and Future Perspectives DOI Creative Commons

Runxing Lin,

Ziyu Huang, Yu Liu

et al.

Biosensors, Journal Year: 2025, Volume and Issue: 15(3), P. 191 - 191

Published: March 17, 2025

Cardiovascular diseases have long been a major challenge to human health, and the treatment differences caused by individual variability remain unresolved. In recent years, personalized cardiovascular drug therapy has attracted widespread attention. This paper reviews strategies for achieving through traditional dynamic monitoring multidimensional data integration analysis. It focuses on key technologies monitoring, based differences, By systematically reviewing relevant literature, main challenges in current research proposed potential directions future studies were summarized.

Language: Английский

Citations

0

Role of electrochemical nanobiosensors in colorectal cancer precision medicine DOI Open Access
Andrés F. Cruz‐Pacheco, Danilo Echeverri, Jahir Orozco

et al.

TrAC Trends in Analytical Chemistry, Journal Year: 2023, Volume and Issue: 170, P. 117467 - 117467

Published: Nov. 30, 2023

Language: Английский

Citations

10

Emerging technologies: analytical lab vs. clinical lab perspective. Common goals and gaps to be filled in the pursuit of green and sustainable solutions DOI
Barbara Bojko

Analytical and Bioanalytical Chemistry, Journal Year: 2024, Volume and Issue: 416(9), P. 2117 - 2124

Published: Jan. 22, 2024

Language: Английский

Citations

3

Electrochemical immunosensing of walnut and hazelnut allergenic proteins in processed foods DOI Creative Commons
Sofiia Tvorynska, Alba Civera, María Gamella

et al.

Sensing and Bio-Sensing Research, Journal Year: 2024, Volume and Issue: 44, P. 100644 - 100644

Published: March 26, 2024

Nuts are a well-known cause of food allergy and, once this has been diagnosed, due to the likelihood cross-sensitization multiple tree nut allergens, their strict avoidance from diet is advisable. In context, we present electrochemical bioplatforms detect traces hazelnut and walnut in processed foods through determination respective allergenic proteins Cor 9 Jug r 1 fast sensitive assay. First, evaluation single both was performed by building sandwich immunoconjugates on surface magnetic microbeads relying specific antibodies unmodified or conjugated horseradish peroxidase. Amperometric transduction made upon trapping bioconjugates disposable carbon electrodes, using hydroquinone/hydrogen peroxide system. The great analytical performance achieved with individual platforms (detection limits 0.12 0.56 ng mL−1 for 9, respectively), led us dual quantification raw dough baked cookies incurred ground nuts. developed method allowed detecting 0.0025% 0.00002% results comparable those provided ELISA techniques. feasibility performing allergens run demonstrated.

Language: Английский

Citations

3

Disposable amperometric biotool for peanut detection in processed foods by targeting a chloroplast DNA marker DOI Creative Commons
María Gamella,

María Isabel Ballesteros,

Víctor Ruiz‐Valdepeñas Montiel

et al.

Talanta, Journal Year: 2024, Volume and Issue: 277, P. 126350 - 126350

Published: June 2, 2024

This work reports the development and application of a disposable amperometric sensor built on magnetic microcarriers coupled to an Express PCR strategy amplify specific DNA fragment chloroplast trnH-psbA. The procedure involves selective capture 68-mer synthetic target (or unmodified products) through sandwich hybridization with RNA probe-modified streptavidin MBs signaling probes, labeled using antibodies heteroduplexes secondary tagged horseradish peroxidase. Amperometric measurements were performed screen-printed electrodes H

Language: Английский

Citations

2

High-Performance ZnO:CuO Composite-Based Fiber-Shaped Electrode for Non-Enzymatic Glucose Sensing in Biological Fluids DOI
Huimin Yuan, Muhammad Hilal, Yasir Ali

et al.

Surfaces and Interfaces, Journal Year: 2024, Volume and Issue: 54, P. 105266 - 105266

Published: Oct. 12, 2024

Language: Английский

Citations

2

Synergistic ZnO-NiO composites for superior Fiber-Shaped Non-Enzymatic glucose sensing DOI

Zuolong Song,

Muhammad Hilal, Hany S. Abdo

et al.

Journal of Industrial and Engineering Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 1, 2024

Language: Английский

Citations

2

Electrochemical bioanalysis: All that still hides the tip of the iceberg DOI Creative Commons
Susana Campuzano, José M. Pingarrón

Current Opinion in Electrochemistry, Journal Year: 2023, Volume and Issue: 41, P. 101359 - 101359

Published: July 27, 2023

The tremendous advances in electrochemical biosensing that have occurred recently, highlighting as never before the versatility and adaptability of resulting biotools, together with innovations natural-inspired bioreceptor production, electrode substrate fabrication, miniaturizable electronics, materials science, digitization artificial intelligence can empower changed perception what we seen offer us. This minireview aims to give a brief current bird's eye view most recent involving design, manufacturing, characteristics applications, supported by references broaden deepen concepts. goal is convince reader bioanalysis has so far only shown us small part its wide multifaceted world which will continue be privileged witnesses coming years.

Language: Английский

Citations

6

Carbon nanomaterial-based electrochemical sensor in biomedical application, a comprehensive study DOI Open Access

S.K. Majumdar,

Razu Shahazi, Amirul Islam Saddam

et al.

Characterization and Application of Nanomaterials, Journal Year: 2024, Volume and Issue: 7(1), P. 4654 - 4654

Published: April 12, 2024

Recently, carbon nanocomposites have garnered a lot of curiosity because their distinctive characteristics and extensive variety possible possibilities. Among all these applications, the development sensors with electrochemical properties based on for use in biomedicine has shown as an area potential. These are suitable assortment biomedical such prescribing medications, disease diagnostics, biomarker detection. They many benefits, including outstanding sensitivity, selectivity, low limitations This comprehensive review aims to provide in-depth analysis recent advancements nanocomposites-based applications. The different types nanomaterials used sensor fabrication, synthesis methods, functionalization techniques employed enhance sensing been discussed. Furthermore, we enumerate numerous biological uses nanocomposites, among them employment illness diagnosis, physiological parameter monitoring, biomolecule challenges prospects applications also Overall, this highlights tremendous potential nanomaterial-based revolutionizing research clinical diagnostics.

Language: Английский

Citations

1