Genipin crosslinked polysaccharide packaging films: an eco-friendly and innovative strategy to improve the performance of food packaging materials

Carbohydrate Polymer Technologies and Applications, Год журнала: 2025, Номер unknown, С. 100732 - 100732

Опубликована: Фев. 1, 2025

Язык: Английский

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Genipin—Simple but Significant Bioactive Iridoid for Therapeutical Application and Beyond: A Review

Life, Год журнала: 2025, Номер 15(2), С. 159 - 159

Опубликована: Янв. 23, 2025

Genipin is a non-glycosidic iridoid isolated mainly from the fruits of Gardenia jasminoides and Genipa americana. It active ingredient in extracts these plants, responsible for their anti-inflammatory hepatoprotective effects. In several vitro tests, its anti-proliferative activity against tumour cell lines has been demonstrated, due to ability specifically inhibit UCP2 protein STAT3 activation, significant increase cytotoxicity anticancer drugs was observed co-treatment with genipin. recent years, importance genipin increased possibility using this as biocompatible low potent crosslinking agent manufacture dressings, tissue engineering, component drug carrier system production food packaging. also substrate blue pigment used additive fabric pigment, other applications. Due documented cases hepatotoxicity, derived it are being investigated effective safe therapeutic non-drug use. The current paper discusses selected aspects chemistry, use interesting compound.

Язык: Английский

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Machine Learning-Based Process Optimization in Biopolymer Manufacturing: A Review

Polymers, Год журнала: 2024, Номер 16(23), С. 3368 - 3368

Опубликована: Ноя. 29, 2024

The integration of machine learning (ML) into material manufacturing has driven advancements in optimizing biopolymer production processes. ML techniques, applied across various stages production, enable the analysis complex data generated throughout identifying patterns and insights not easily observed through traditional methods. As sustainable alternatives to petrochemical-based plastics, biopolymers present unique challenges due their reliance on variable bio-based feedstocks processing conditions. This review systematically summarizes current applications techniques aiming provide a comprehensive reference for future research while highlighting potential enhance efficiency, reduce costs, improve product quality. also shows role algorithms, including supervised, unsupervised, deep

Язык: Английский

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Genipin-enriched chitosan-Zein nanoparticles for improved curcumin encapsulation

International Journal of Biological Macromolecules, Год журнала: 2024, Номер unknown, С. 138555 - 138555

Опубликована: Дек. 1, 2024

Язык: Английский

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Entrapment of Geobacillus kaustophilus lipase in ZIF-8 and cross-linking with genipin for biodiesel production from vegetable oils

Molecular Catalysis, Год журнала: 2025, Номер 576, С. 114919 - 114919

Опубликована: Фев. 19, 2025

Язык: Английский

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From nature to applications: Laccase immobilization onto bio-based materials for eco-conscious environmental remediation

International Journal of Biological Macromolecules, Год журнала: 2025, Номер 307, С. 142157 - 142157

Опубликована: Март 15, 2025

Язык: Английский

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Advances in bioink-based 3D printed scaffolds: optimizing biocompatibility and mechanical properties for bone regeneration

Biomaterials Science, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

The development of bioink-based 3D-printed scaffolds has revolutionized bone tissue engineering (BTE) by enabling patient-specific and biomimetic constructs for regeneration.

Язык: Английский

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Physicochemical Characterization of Injectable Genipin-Crosslinked Gelatin–Kelulut Honey Hydrogels for Future Cutaneous Tissue Loss

Polymers, Год журнала: 2025, Номер 17(9), С. 1129 - 1129

Опубликована: Апрель 22, 2025

Chronic wounds, particularly those associated with conditions like diabetes, present significant challenges in healthcare due to prolonged healing and high susceptibility infections. This study investigates the development of injectable hydrogels composed genipin-crosslinked gelatin Kelulut honey (KH) as novel biomaterials for wound applications. Hydrogels were prepared varying concentrations (w/v) (9% 10%) KH (0.1% 0.5%), genipin (0.1%) acting a crosslinker. The physicochemical properties extensively evaluated, including swelling ratio, water vapor transmission rate (WVTR), contact angle, porosity, enzymatic degradation, surface roughness. results showed that incorporation significantly enhanced hydrogels, 9GE_0.1KH formulation demonstrating ratio 742.07 ± 89.61% compared 500% control 9GE formulation. WVTR values KH-incorporated ranged from 1670.60 236.87 g/m2h 2438.92 190.90 g/m2h, which within ideal range (1500–2500 g/m2h) healing. Contact angle measurements indicated improved hydrophilicity, showing 42.14° 7.52° 60° 11.66° 10GE Biodegradation rates slightly higher KH-modified (0.079 0.006 mg/h 9GE_0.1KH), but all remained acceptable limits. These findings suggest gelatin-KH offer promising scaffold potential applications tissue engineering three-dimensional (3D) bioprinting technologies.

Язык: Английский

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Crosslinked chitosan-benzil/microalgae/kronos (titanium dioxide) biocomposite for the removal of brilliant green dye: Response surface methodology optimisation and mechanism

International Journal of Biological Macromolecules, Год журнала: 2025, Номер unknown, С. 144005 - 144005

Опубликована: Май 1, 2025

Язык: Английский

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Spray‐Dried Microencapsulation of Probiotics With Genipin‐Crosslinked Whey Protein Isolate for Enhanced Stability in Fortified Instant Cereal Drinks

Journal of Food Science, Год журнала: 2025, Номер 90(5)

Опубликована: Май 1, 2025

ABSTRACT Probiotics face significant challenges during processing, storage, and gastrointestinal transit, leading to reduced viability diminished health benefits in functional foods. This study investigated the effects of genipin crosslinking (2.5, 5, 10 mM) on structural properties whey protein isolate (WPI) as an encapsulant for Limosilactobacillus reuteri KUB‐AC5 probiotic‐fortified cereal instant drinks. Fourier transform infrared spectroscopy (FTIR) confirmed covalent bonding between WPI, forming a reinforced matrix with surface hydrophobicity, increased tension, enhanced turbidity. Differential scanning calorimetry (DSC) further demonstrated that initially improved thermal stability, WPI‐2.5G exhibiting highest denaturation temperature (78.97°C), enthalpy values (0.54 J/g), before decreasing at higher concentrations due potential aggregation. significantly probiotic survival after spray drying (8.13%), flow cytometry confirming proportion intact cells fewer injured cells, indicating protective functionality. After 4 months storage 4°C 25°C, maintained superior viability, 2.69 × 9 CFU/serving (12.44% survival) 3.47 10⁶ (0.02% survival), respectively, compared other formulations. Furthermore, exhibited rates reconstitution (2.98 10⁸ CFU/serving) dynamic digestion (5.69 CFU/serving), exceeding recommended threshold efficacy. These findings demonstrate crosslinking, particularly 2.5 mM, offers promising strategy enhancing developing heat‐stable, nondairy beverages.

Язык: Английский

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