Role of crosslinkers in advancing chitosan-based biocomposite scaffolds for bone tissue engineering: A comprehensive review DOI

Venkatasubramanian Sai Krishna,

Velan Subashini,

Adithya Hariharan

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 283, P. 137625 - 137625

Published: Nov. 14, 2024

Language: Английский

Genipin crosslinked polysaccharide packaging films: an eco-friendly and innovative strategy to improve the performance of food packaging materials DOI Creative Commons
Arezou Khezerlou, Mahmood Alizadeh Sani, Jong‐Whan Rhim

et al.

Carbohydrate Polymer Technologies and Applications, Journal Year: 2025, Volume and Issue: unknown, P. 100732 - 100732

Published: Feb. 1, 2025

Language: Английский

Citations

2

Genipin—Simple but Significant Bioactive Iridoid for Therapeutical Application and Beyond: A Review DOI Creative Commons
Danuta Sobolewska, Agnieszka Galanty, Karolina Grabowska

et al.

Life, Journal Year: 2025, Volume and Issue: 15(2), P. 159 - 159

Published: Jan. 23, 2025

Genipin is a non-glycosidic iridoid isolated mainly from the fruits of Gardenia jasminoides and Genipa americana. It active ingredient in extracts these plants, responsible for their anti-inflammatory hepatoprotective effects. In several vitro tests, its anti-proliferative activity against tumour cell lines has been demonstrated, due to ability specifically inhibit UCP2 protein STAT3 activation, significant increase cytotoxicity anticancer drugs was observed co-treatment with genipin. recent years, importance genipin increased possibility using this as biocompatible low potent crosslinking agent manufacture dressings, tissue engineering, component drug carrier system production food packaging. also substrate blue pigment used additive fabric pigment, other applications. Due documented cases hepatotoxicity, derived it are being investigated effective safe therapeutic non-drug use. The current paper discusses selected aspects chemistry, use interesting compound.

Language: Английский

Citations

1

Machine Learning-Based Process Optimization in Biopolymer Manufacturing: A Review DOI Open Access
Ivan Malashin,

D. A. Martysyuk,

В С Тынченко

et al.

Polymers, Journal Year: 2024, Volume and Issue: 16(23), P. 3368 - 3368

Published: Nov. 29, 2024

The integration of machine learning (ML) into material manufacturing has driven advancements in optimizing biopolymer production processes. ML techniques, applied across various stages production, enable the analysis complex data generated throughout identifying patterns and insights not easily observed through traditional methods. As sustainable alternatives to petrochemical-based plastics, biopolymers present unique challenges due their reliance on variable bio-based feedstocks processing conditions. This review systematically summarizes current applications techniques aiming provide a comprehensive reference for future research while highlighting potential enhance efficiency, reduce costs, improve product quality. also shows role algorithms, including supervised, unsupervised, deep

Language: Английский

Citations

5

Entrapment of Geobacillus kaustophilus lipase in ZIF-8 and cross-linking with genipin for biodiesel production from vegetable oils DOI
Ahmet Tülek

Molecular Catalysis, Journal Year: 2025, Volume and Issue: 576, P. 114919 - 114919

Published: Feb. 19, 2025

Language: Английский

Citations

0

From nature to applications: Laccase immobilization onto bio-based materials for eco-conscious environmental remediation DOI
Praveen Kumar Mehta,

Jyotsna Kiran Peter,

Arun Kumar

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: 307, P. 142157 - 142157

Published: March 15, 2025

Language: Английский

Citations

0

Advances in bioink-based 3D printed scaffolds: optimizing biocompatibility and mechanical properties for bone regeneration DOI
Pawan Kumar, Jitender Sharma, Ravinder Kumar

et al.

Biomaterials Science, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

The development of bioink-based 3D-printed scaffolds has revolutionized bone tissue engineering (BTE) by enabling patient-specific and biomimetic constructs for regeneration.

Language: Английский

Citations

0

Physicochemical Characterization of Injectable Genipin-Crosslinked Gelatin–Kelulut Honey Hydrogels for Future Cutaneous Tissue Loss DOI Open Access
Raniya Razif, Nur Izzah Md Fadilah, Manira Maarof

et al.

Polymers, Journal Year: 2025, Volume and Issue: 17(9), P. 1129 - 1129

Published: April 22, 2025

Chronic wounds, particularly those associated with conditions like diabetes, present significant challenges in healthcare due to prolonged healing and high susceptibility infections. This study investigates the development of injectable hydrogels composed genipin-crosslinked gelatin Kelulut honey (KH) as novel biomaterials for wound applications. Hydrogels were prepared varying concentrations (w/v) (9% 10%) KH (0.1% 0.5%), genipin (0.1%) acting a crosslinker. The physicochemical properties extensively evaluated, including swelling ratio, water vapor transmission rate (WVTR), contact angle, porosity, enzymatic degradation, surface roughness. results showed that incorporation significantly enhanced hydrogels, 9GE_0.1KH formulation demonstrating ratio 742.07 ± 89.61% compared 500% control 9GE formulation. WVTR values KH-incorporated ranged from 1670.60 236.87 g/m2h 2438.92 190.90 g/m2h, which within ideal range (1500–2500 g/m2h) healing. Contact angle measurements indicated improved hydrophilicity, showing 42.14° 7.52° 60° 11.66° 10GE Biodegradation rates slightly higher KH-modified (0.079 0.006 mg/h 9GE_0.1KH), but all remained acceptable limits. These findings suggest gelatin-KH offer promising scaffold potential applications tissue engineering three-dimensional (3D) bioprinting technologies.

Language: Английский

Citations

0

Genipin-enriched chitosan-Zein nanoparticles for improved curcumin encapsulation DOI
Sha Liu, Husnain Raza, Chengsheng Jia

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: unknown, P. 138555 - 138555

Published: Dec. 1, 2024

Language: Английский

Citations

3

Crosslinked chitosan-benzil/microalgae/kronos (titanium dioxide) biocomposite for the removal of brilliant green dye: Response surface methodology optimisation and mechanism DOI

Elmira Kashi,

Ali H. Jawad, Siti Norasmah Surip

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 144005 - 144005

Published: May 1, 2025

Language: Английский

Citations

0

Genipin crosslinked hydrogels for food and biomedical applications: A scientometric review DOI
Dong Xu, Y. H. Hui, Wei Zhang

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 282, P. 137478 - 137478

Published: Nov. 12, 2024

Language: Английский

Citations

2