Drosophila sechellia: A Genetic Model for Behavioral Evolution and Neuroecology

Annual Review of Genetics, Год журнала: 2021, Номер 55(1), С. 527 - 554

Опубликована: Сен. 17, 2021

Defining the mechanisms by which animals adapt to their ecological niche is an important problem bridging evolution, genetics, and neurobiology. We review establishment of a powerful genetic model for comparative behavioral analysis neuroecology, Drosophila sechellia. This island-endemic fly species closely related several cosmopolitan generalists, including melanogaster, but has evolved extreme specialism, feeding reproducing exclusively on noni fruit tropical shrub Morinda citrifolia. first describe development use approaches facilitate genotype/phenotype associations in these drosophilids. Next, we survey behavioral, physiological, morphological adaptations D. sechellia throughout its life cycle outline our current understanding cellular basis traits. Finally, discuss principles this knowledge begins establish context host specialization, speciation, neurobiology evolution consider open questions challenges field.

Язык: Английский

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Drosophila olfaction: past, present and future

Proceedings of the Royal Society B Biological Sciences, Год журнала: 2022, Номер 289(1989)

Опубликована: Дек. 14, 2022

Among the many wonders of nature, sense smell fly Drosophila melanogaster might seem, at first glance, esoteric interest. Nevertheless, for over a century, ‘nose’ this insect has been an extraordinary system to explore questions in animal behaviour, ecology and evolution, neuroscience, physiology molecular genetics. The insights gained are relevant our understanding sensory biology vertebrates, including humans, other species, encompassing those detrimental human health. Here, I present overview current knowledge D. olfaction, from molecules behaviours, with emphasis on historical motivations studies illustration how technical innovations have enabled advances. also highlight some pressing long-term questions.

Язык: Английский

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Synaptic connectome of a neurosecretory network in the Drosophila brain

bioRxiv (Cold Spring Harbor Laboratory), Год журнала: 2024, Номер unknown

Опубликована: Авг. 29, 2024

Abstract Hormones mediate inter-organ signaling which is crucial in orchestrating diverse behaviors and physiological processes including sleep activity, feeding, growth, metabolism reproduction. The pars intercerebralis lateralis insects represent major hubs contain neurosecretory cells (NSC) that produce various hormones. To obtain insight into how hormonal regulated, we have characterized the synaptic connectome of NSC adult Drosophila brain. Identification neurons providing inputs to multiple subtypes implicates diuretic hormone 44-expressing as a coordinator physiology behavior. Surprisingly, despite most having dendrites subesophageal zone (primary taste processing center), gustatory are largely indirect. We also deciphered pathways via olfactory relayed NSC. Further, our analyses revealed substantial from descending NSC, suggesting regulate both endocrine motor output synchronize changes with appropriate behaviors. In contrast inputs, sparse mostly mediated by corazonin Therefore, additionally determine putative paracrine interconnectivity between peripheral tissues analyzing single-cell transcriptomic datasets. Our comprehensive characterization network provides platform understand complex networks they orchestrate animal physiology.

Язык: Английский

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The neuroecology of olfaction in bees

Current Opinion in Insect Science, Год журнала: 2023, Номер 56, С. 101018 - 101018

Опубликована: Фев. 25, 2023

The focus of bee neuroscience has for a long time been on only handful social honeybee and bumblebee species, out thousands bees species that have described. On the other hand, information about chemical ecology is much more abundant. Here we attempted to compile scarce olfactory systems across species. We also review major categories intra- inter-specific behaviors bees, with specific recent literature. finish by discussing most promising avenues research in near future.

Язык: Английский

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Multistep automated synthesis of pharmaceuticals

Trends in Chemistry, Год журнала: 2023, Номер 5(6), С. 432 - 445

Опубликована: Апрель 21, 2023

Язык: Английский

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Evolution at multiple processing levels underlies odor-guided behavior in the genus Drosophila

Current Biology, Год журнала: 2023, Номер 33(22), С. 4771 - 4785.e7

Опубликована: Окт. 6, 2023

Язык: Английский

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Olfactory stimuli and moonwalker SEZ neurons can drive backward locomotion in Drosophila

Current Biology, Год журнала: 2022, Номер 32(5), С. 1131 - 1149.e7

Опубликована: Фев. 8, 2022

How different sensory stimuli are collected, processed, and further transformed into a coordinated motor response is fundamental question in neuroscience. In particular, the internal external conditions that drive animals to switch backward walking mechanisms by which nervous system supports such behavior still unknown. fruit flies, moonwalker descending neurons (MDNs) considered command-type for locomotion as they receive visual mechanosensory inputs transmit motor-related signals downstream elicit locomotion. Whether other modalities converge onto MDNs, central brain activate whether retreat-driving pathways exist currently Here, we show olfactory stimulation can MDN-mediated Moreover, identify subesophageal zone (MooSEZs), pair of bilateral neurons, trigger straight rotational MooSEZs act via postsynaptic MDNs neurons. Although respond input, not required odor-induced walking. Thus, this work reveals an important modality input novel set presynaptic driving MDN-independent pathway.

Язык: Английский

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Genetics and the Evolution of Prezygotic Isolation

Cold Spring Harbor Perspectives in Biology, Год журнала: 2023, Номер 16(2), С. a041439 - a041439

Опубликована: Окт. 17, 2023

Richard M. Merrill1, Henry Arenas-Castro2, Anna F. Feller3,4, Julia Harenčár5, Matteo Rossi1, Matthew A. Streisfeld6 and Kathleen Kay5 1Faculty of Biology, Division Evolutionary LMU Munich, 82152 Planegg-Martinsried, Germany 2School Biological Sciences, University Queensland, St. Lucia, Queensland 4072, Australia 3Department Organismic Harvard University, Cambridge, Massachusetts 02138, USA 4Arnold Arboretum Boston, 02131, 5Department Ecology California, Santa Cruz, California 95060, 6Institute Evolution, Oregon, Eugene, Oregon 97403-5289, Correspondence: merrill{at}bio.lmu.de; kmkay{at}ucsc.edu

Язык: Английский

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En route to resources: Foraging strategies of plant‐associated insects to identify resources in complex dynamic environments

Functional Ecology, Год журнала: 2024, Номер 38(8), С. 1664 - 1682

Опубликована: Июль 11, 2024

Abstract In plant‐associated communities, foraging insects aim to find different resources of interest. Herbivores look for the most nutritious plant tissues, pollinators sweet nectar and protein‐rich pollen, carnivores their preferred prey. Although these foragers resources, they face similar problems: resource cues are often highly variable need be detected in complex environments among non‐resources. Search templates—a subset stimuli that is likely correlated with occurrence a particular resource—help across trophic levels resources. However, search‐template‐based can also cause perception errors. Here, we synthesize knowledge on by from functional groups belonging reveal common problems experienced strategies solve such problems. We focus mostly volatile‐based because this searching strategy best studied groups. argue search templates both multimodal (including multiple trait types, e.g. odour visual) hierarchical steps). plastic updated experience match dynamic environment over time. By comparing spanning levels, have identified important missing gaps cue use which should addressed future order reduce asymmetries about foraging. propose way achieve goal arguing studies less well investigated advance rapidly borrowing, testing adjusting already available hypotheses theories formulated other insect Knowledge will give new insights into evolution behaviour ecological help predict consequences large‐scale human‐made disturbances optimize insect‐delivered ecosystem services (pollination biological control) cropping systems. Read free Plain Language Summary article Journal blog.

Язык: Английский

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Taste adaptations associated with host specialization in the specialistDrosophila sechellia

Journal of Experimental Biology, Год журнала: 2023, Номер 226(3)

Опубликована: Янв. 13, 2023

ABSTRACT Chemosensory-driven host plant specialization is a major force mediating insect ecological adaptation and speciation. Drosophila sechellia, species endemic to the Seychelles islands, feeds oviposits on Morinda citrifolia almost exclusively. This fruit harmless D. sechellia but toxic other Drosophilidae, including closely related generalists simulans melanogaster, because of its high content fatty acids. While several olfactory adaptations sechellia’s preference for have been uncovered, role taste has much less examined. We found that reduced feeding aversion bitter compounds acids are aversive melanogaster simulans. The loss canavanine, coumarin arose in lineage, as sister showed responses akin those melanogaster. increased towards M. citrifolia. These results line with genes encode gustatory receptors (GRs) two GR which lost GR39a.a GR28b.a, influence reduction some compounds. Also, appetite prominent acid compound relatives. Our support hypothesis changes system, specifically sensitivity deter generalist ancestors, contribute host.

Язык: Английский

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