BMC Public Health, Год журнала: 2024, Номер 24(1)
Опубликована: Окт. 9, 2024
Stroke is the leading cause of death in middle-aged and elderly people China. Insulin resistance (IR) sarcopenia are both closely associated with metabolic diseases. However, relationship between these two indicators stroke has not been fully investigated. The aim this study was to investigate IR risk new-onset stroke.
Язык: Английский
Archives of Pharmacal Research, Год журнала: 2024, Номер 47(4), С. 301 - 324
Опубликована: Апрель 1, 2024
Язык: Английский
Процитировано
12
International Journal of Diabetes in Developing Countries, Год журнала: 2025, Номер unknown
Опубликована: Фев. 10, 2025
Язык: Английский
Процитировано
1
Aging Clinical and Experimental Research, Год журнала: 2025, Номер 37(1)
Опубликована: Фев. 27, 2025
Abstract Background Patients with sarcopenia often experience cognitive decline, affecting cortical structures, but the causal link remains unclear. We used bidirectional Mendelian randomization (MR) to explore relationship between sarcopenia-related traits and structure. Methods selected genetic variables from genome-wide association study data. Three different MR methods were used: inverse-variance weighted analysis, MR-Egger regression, median test. For significant estimates, we further conducted Cochran’s Q test, intercept leave-one-out analyses, MR-PRESSO assess heterogeneity. Results In forward appendicular lean mass (ALM) decreased thickness (TH) of lateral occipital gyrus increased TH pars opercularis (β = -0.0079 mm, 95% CI: -0.0117 mm -0.0041 P < 0.0001; β 0.0080 0.0042 0.0117 0.0001). reverse a negative correlation was found bankssts ALM, while positive correlations observed frontal pole, rostral anterior cingulate, temporal ALM. The pole positively correlated right hand grip strength (HGS-R) 0.1596 0.1349 0.1843 0.0001), triangularis left-hand (HGS-L) 0.3251 0.2339 0.4163 Conclusions Sarcopenia-related structure have effects, supporting muscle-brain axis theory. This links neurocognitive diseases provides new strategies for prevention intervention both decline.
Язык: Английский
Процитировано
1
Frontiers in Nutrition, Год журнала: 2024, Номер 11
Опубликована: Март 8, 2024
Background Early-onset sarcopenia refers to the progressive loss of muscle mass and function that occurs at an early age. This condition perpetuates vicious cycle is associated with adverse outcomes. It important identify contributing factors for intervention prevention. While diet known impact mass, association B vitamins early-onset remains unexplored. Objectives To investigate intake risk in a cross-sectional study. Methods We conducted data analysis on total 8,711 participants aged between 20 59 years who took part National Health Nutrition Examination Survey (NHANES) from 2011 2018. was defined as SMI measured by DXA one standard deviation below sex-specific mean reference population. (B1, B2, B3, B6, B9, B12) assessed 24-h dietary recall. used weighted multiple logistic regression RCS models estimate OR 95% CI intake, adjusting demographic, physical, lifestyle, comorbidities, nutritional covariates. Results Higher vitamin B1 22% lower (OR = 0.78, 0.63–0.97, p 0.022), higher B2 16% 0.84, 0.74–0.97, 0.012) both genders. Gender-specific analyses showed 28% reduction among males each additional mg 0.72, 0.52–0.97, 0.038), 26% decrease females 0.74, 0.57–0.96, 0.021). No significant differences were found males, or females. The model suggested nonlinear relationship ( P Overall 0.001, Nonlinear 0.033), plateau effect above 3 mg/d. Conclusion may sarcopenia, gender differences. suggests potential increasing these through supplements. Further research warranted elucidate mechanisms design targeted interventions.
Язык: Английский
Процитировано
5
Seizure, Год журнала: 2025, Номер 125, С. 162 - 171
Опубликована: Янв. 5, 2025
Язык: Английский
Процитировано
0
Archives of Gerontology and Geriatrics, Год журнала: 2025, Номер 132, С. 105787 - 105787
Опубликована: Фев. 21, 2025
Язык: Английский
Процитировано
0
Frontiers in Medicine, Год журнала: 2025, Номер 12
Опубликована: Фев. 26, 2025
Sarcopenia, characterized by the gradual decline of muscle mass and strength, seriously affects health mobility older adults. The purpose this study is to investigate risk factors for sarcopenia, particularly relationship between chronic diseases lifestyle in individuals aged 60 over. This used data from Longitudinal Study on Health Retirement China (CHARLS) collected 2011 2015. All eligible participants were classified according standards established Asian Sarcopenia Working Group 2019. evaluation sarcopenia was based a comprehensive score across five dimensions: assistance walking, rise chair, climb stairs, falls. A multivariate logistic regression model employed explore sarcopenia. significantly influenced multiple factors. Key findings include association past drinking an increased (HR = 2.198, 95% CI: 1.072-4.560, p < 0.05), indicating that with history have more than twice compared non-drinkers. Chronic such as stroke also associated elevated 3.137, 1.128-8.721, 0.05). Conversely, participation social activities reduced 0.482, 0.265-0.876, three-piece spline revealed nonlinear physical activity initial followed increase levels rose. Moderate-intensity approximately 35% ≈ 0.65). However, high-intensity led rebound risk, increasing likelihood relative moderate activity. Similarly, adequate sleep duration whereas excessive counteracted benefit. underscore critical role modifications balanced mitigating among Implementing targeted interventions high-risk groups essential reduce incidence
Язык: Английский
Процитировано
0
Maturitas, Год журнала: 2025, Номер 196, С. 108233 - 108233
Опубликована: Март 4, 2025
Язык: Английский
Процитировано
0
Metabolism, Год журнала: 2025, Номер 169, С. 156272 - 156272
Опубликована: Апрель 19, 2025
Язык: Английский
Процитировано
0
Gerontology, Год журнала: 2024, Номер 70(8), С. 823 - 830
Опубликована: Янв. 1, 2024
Sarcopenia associated with stroke can significantly impact patient prognosis; however, the current standard diagnostic methods for sarcopenia are rarely used in patients. Therefore, aim of study was to investigate whether temporal muscle thickness (TMT) or area (TMA) could serve as a surrogate marker measuring skeletal mass.
Язык: Английский
Процитировано
3