Biotechnological Approaches to Producing Natural Antioxidants: Anti-Ageing and Skin Longevity Prospects DOI Open Access
Sarah Bouzroud,

Ezzouhra El Maaiden,

Mansour Sobeh

и другие.

International Journal of Molecular Sciences, Год журнала: 2023, Номер 24(2), С. 1397 - 1397

Опубликована: Янв. 11, 2023

Plants are the main source of bioactive compounds that can be used for formulation cosmetic products. Plant extracts have numerous proven health benefits, among which anti-ageing and skin-care properties. However, with increased demand plant-derived products, there is a crucial prerequisite establishing alternative approaches to conventional methods ensure sufficient biomass sustainable production. tissue culture techniques, such as in vitro root cultures, micropropagation, or callogenesis, offer possibility produce considerable amounts independent external factors may influence their This production also significantly implementation other biotechnological elicitation, metabolic engineering, precursor and/or nutrient feeding, immobilization, permeabilization. work aimed evaluate potential tools producing compounds, focus on properties, development green-label cosmeceutical In addition, some examples demonstrating use plant techniques high-value ingredients applications addressed, showing importance these

Язык: Английский

Synthetic biology strategies for microbial biosynthesis of plant natural products DOI Creative Commons

Aaron Cravens,

James T. Payne,

Christina D. Smolke

и другие.

Nature Communications, Год журнала: 2019, Номер 10(1)

Опубликована: Май 13, 2019

Abstract Metabolic engineers endeavor to create a bio-based manufacturing industry using microbes produce fuels, chemicals, and medicines. Plant natural products (PNPs) are historically challenging ubiquitous in medicines, flavors, fragrances. Engineering PNP pathways into new hosts requires finding or modifying suitable host accommodate the pathway, planning implementing biosynthetic route compound, discovering engineering enzymes for missing steps. In this review, we describe recent developments metabolic at level of host, enzyme, discuss how field is approaching ever more complex opportunities.

Язык: Английский

Процитировано

334

Application of genetics and biotechnology for improving medicinal plants DOI
Mohsen Niazian

Planta, Год журнала: 2019, Номер 249(4), С. 953 - 973

Опубликована: Фев. 4, 2019

Язык: Английский

Процитировано

155

Biosynthesis and regulation of anthocyanin pathway genes DOI

L. Sunil,

Nandini P. Shetty

Applied Microbiology and Biotechnology, Год журнала: 2022, Номер 106(5-6), С. 1783 - 1798

Опубликована: Фев. 16, 2022

Язык: Английский

Процитировано

126

Plant probiotics – Endophytes pivotal to plant health DOI Creative Commons
Shiv Shanker Pandey, Rahul Jain, Priyanka Bhardwaj

и другие.

Microbiological Research, Год журнала: 2022, Номер 263, С. 127148 - 127148

Опубликована: Июль 27, 2022

Язык: Английский

Процитировано

69

Plant Cell Cultures: Biofactories for the Production of Bioactive Compounds DOI Creative Commons
Vishwas A. Bapat, P. B. Kavi Kishor, Jalaja Naravula

и другие.

Agronomy, Год журнала: 2023, Номер 13(3), С. 858 - 858

Опубликована: Март 15, 2023

Plants have long been exploited as a sustainable source of food, flavors, agrochemicals, colors, therapeutic proteins, bioactive compounds, and stem cell production. However, plant habitats are being briskly lost due to scores environmental factors human disturbances. This necessitates finding viable alternative technology for the continuous production compounds that utilized in food healthcare. The high-value natural products often challenging synthesize chemically since they accumulate meager quantities. isolation purification from plants is time-consuming, labor-intensive, involves cumbersome extraction procedures. demands options, culture system offers easy downstream Retention metabolic cues plants, scale-up facility, use cells cosmetics industry, engineering (especially rebuilding pathways microbes) some advantages synthesis accumulation targeted metabolites creation high yielding factories. In this article, we discuss suspension cultures vitro manipulation compounds. Further, new advances application industry bioprinting.

Язык: Английский

Процитировано

56

Bioreactor systems for micropropagation of plants: present scenario and future prospects DOI Creative Commons
Hosakatte Niranjana Murthy, Kadanthottu Sebastian Joseph, Kee‐Yoeup Paek

и другие.

Frontiers in Plant Science, Год журнала: 2023, Номер 14

Опубликована: Апрель 19, 2023

Plant micropropagation has been adapted in the fields of agriculture, horticulture, forestry, and other related for large-scale production elite plants. The use liquid media adoption bioreactors have escalated healthy Several liquid-phase, gas-phase, temporary immersion, modified used plant propagation. design, principle, operational mode, merits, demerits various regeneration propagules, such as bulblets, cormlets, rhizomes, microtubers, shoots (subsequent rooting), somatic embryos, are discussed here. In addition, parameters that affect with suitable examples.

Язык: Английский

Процитировано

50

Phenolic Compounds from New Natural Sources—Plant Genotype and Ontogenetic Variation DOI Creative Commons
Renata Nurzyńska-Wierdak

Molecules, Год журнала: 2023, Номер 28(4), С. 1731 - 1731

Опубликована: Фев. 11, 2023

Phenolic compounds (PCs) are widespread secondary metabolites with potent biological activity. Their sources mainly plants from cultivated and natural states, providing valuable protective health-promoting extracts. The wide activity of PCs (antioxidant, anti-inflammatory, antimicrobial, antiatherosclerotic, antidiabetic, antiallergic, prebiotic, antimutagenic) means that new constantly being sought, as exemplified by extracting these tissue culture or agricultural by-products. Plant phenols show marked qualitative quantitative variation not only at different genetic levels (between within species clones) but also between physiological developmental stages. Assessing seasonal variations in phenolic content allows for selecting the best time to harvest plant. Learning about causes PCs' variability putting this knowledge into practice can significantly increase yields extract most compounds. properties resulting consuming products rich plant undeniable, so it is worth promoting high-phenolic a regular diet. This paper presents an overview use potential therapeutic alternatives. Additionally, factors complex genome ontogeny levels, relevant practical terms basis further scientific research, presented.

Язык: Английский

Процитировано

44

Enhancing secondary metabolite production in plants: Exploring traditional and modern strategies DOI Creative Commons

Nidhi Selwal,

Farida Rahayu, Anik Herwati

и другие.

Journal of Agriculture and Food Research, Год журнала: 2023, Номер 14, С. 100702 - 100702

Опубликована: Июнь 25, 2023

The biosynthesis of secondary metabolites (SMs) in plants occurs various forms and amounts, their use modern medicine is widespread. Half the human necessities are derived from plant-based commodities, including fuel, cosmetics, pharmaceuticals, building materials, food essentials. Many medicinal plant species utilized for therapeutic properties SMs content, but amount naturally occurring limited. Therefore, conventional novel strategies employed to enhance production bioactive components plants. Traditional methods cost-effective, easy, faster, produce fewer metabolites, while techniques such as metabolic pathways engineering, genome editing, transformation, biotechnology-based substitutions, synthetic biology more expensive offer valuable tools augmenting content. Optimizing culture media signalling involved presents an exciting opportunity increase quantity compounds present. This review summarizes different cultivation used class produced highlights benefits boosting synthesizing using techniques.

Язык: Английский

Процитировано

41

Identification of cucumber circular RNAs responsive to salt stress DOI Creative Commons
Yongxing Zhu, Jianhua Jia, Lei Yang

и другие.

BMC Plant Biology, Год журнала: 2019, Номер 19(1)

Опубликована: Апрель 27, 2019

Circular RNAs (circRNAs) are 3′-5′ head-to-tail covalently closed non-coding RNA that have been proved to play essential roles in many cellular and developmental processes. However, no information relate cucumber circRNAs is available currently, especially under salt stress condition. In this study, we sequenced a total of 2787 were identified, with 1934 root 44 leaf being differentially regulated stress. Characteristics analysis these revealed following features: most them exon (79.51%) they prefer arise from middle exon(s) parent genes (2035/2516); moreover, circularization events (88.3%) use non-canonical-GT/AG splicing signals; last but not least, pairing-driven the major way generate since very few (18) contain sufficient flanking complementary sequences. Annotation enrichment both parental target mRNAs launched uncover functions expressed induced by The results showed may be paly response mediating transcription, signal cell cycle, metabolism adaptation, ion homeostasis related pathways. Moreover, function regulate proline metabolisms through regulating associated biosynthesis degradation genes. present study identified large number annotation their possible biological Our findings will lay solid foundation for further structure studies circRNAs.

Язык: Английский

Процитировано

97

PEG 6000-Stimulated Drought Stress Improves the Attributes of In Vitro Growth, Steviol Glycosides Production, and Antioxidant Activities in Stevia rebaudiana Bertoni DOI Creative Commons
Muhammad Arslan Ahmad, Rabia Javed, Muhammad Adeel

и другие.

Plants, Год журнала: 2020, Номер 9(11), С. 1552 - 1552

Опубликована: Ноя. 12, 2020

This study addresses the favourable effects of drought stress imposed by polyethylene glycol (PEG) 6000 on micropropagated shoots Stevia rebaudiana. Various concentrations, i.e., 0, 0.5, 1, 2, and 4% PEG were applied to nodal shoot explants for four weeks, influence produced growth parameters, bioactive steviol glycosides (rebaudioside A stevioside), nonenzymatic antioxidant activities (total phenolic content (TPC), total flavonoid (TFC), capacity (TAC), reducing power (TRP) 1,1-diphenyl-2-picrylhydrazyl(DPPH)-free radical scavenging activity (FRSA)) was elucidated. The significantly highest yield (92.4% direct organogenesis) secondary metabolites (2.94% Reb A, 2.52% ST, 95.3% DPPH-FRSA, 15.0% TPC, 13.0 µg/mg TFC, 22.3 TAC, 19.8 TRP) production in response abiotic elicitors obtained Murashige Skoog (MS) medium treatment provided with 6000. overall trend significant enhancement dynamics pharmaceutical compounds from control concentration as a defensive against reactive oxygen species (ROS) excess water deficit. is very promising be employed bioreactors get markedly enhanced medicinal importance market.

Язык: Английский

Процитировано

83