Clinical Efficacy of NIBS in Enhancing Neuroplasticity for Stroke Recovery
Journal of Neuroscience Methods,
Год журнала:
2025,
Номер
unknown, С. 110399 - 110399
Опубликована: Фев. 1, 2025
Язык: Английский
Transcranial direct current stimulation for upper and lower limb motor dysfunction after stroke: a systematic review and meta-analysis of randomized controlled trials
Brain Network and Modulation,
Год журнала:
2025,
Номер
4(1), С. 1 - 12
Опубликована: Янв. 1, 2025
Transcranial
direct
current
stimulation
(tDCS)
has
emerged
as
a
promising
noninvasive
intervention
for
motor
recovery
after
stroke,
yet
its
therapeutic
efficacy
remains
unclear.
This
study
was
designed
to
systematically
evaluate
the
effectiveness
of
tDCS
upper
and
lower
extremity
function
in
stroke
patients.
A
comprehensive
search
conducted
randomized
controlled
trials
published
before
February
6,
2025,
across
five
databases:
PubMed,
Embase,
Web
Science,
Cochrane
Library,
Scopus.
The
Fugl-Meyer
Assessment
Scales
Upper
Lower
Extremities
served
primary
evaluation
metrics,
complemented
by
secondary
measures,
including
Action
Research
Arm
Test,
Timed
Up
Go
Barthel
Index.
Two
independent
investigators
screened
literature,
Risk
Bias
Tool
employed
assess
quality
extract
relevant
data.
total
24
were
included
analysis.
Meta-analysis
outcomes
revealed
that
had
positive
effect
on
improving
limb
(mean
difference
(
MD
)
=
1.628,
95%
confidence
interval
CI
):
1.145-2.111,
P
<
0.001)
but
not
improvement
1.133,
:
–0.031–2.298,
0.056).
Subgroup
analyses
optimal
parameters:
anodal
M1
region
1.707,
1.159–2.256),
intensity
≥
0.05
mA/cm
2
1.652,
0.862–2.442),
treatment
duration
exceeding
weeks
1.848,
0.703–2.994).
Notably,
benefits
particularly
evident
during
acute
subacute
rehabilitation
phases.
Current
evidence
suggests
demonstrates
clinically
meaningful
enhancement
patients,
whereas
functional
inconclusive.
Язык: Английский
Comparison of the effects of transcranial direct current stimulation combined with different rehabilitation interventions on motor function in people suffering from stroke-related symptoms: a systematic review and network meta-analysis
Frontiers in Neurology,
Год журнала:
2025,
Номер
16
Опубликована: Июнь 4, 2025
Background
This
study
employs
network
meta-analysis
to
assess
the
efficacy
of
transcranial
direct
current
stimulation
(tDCS)
combined
with
different
rehabilitation
approaches
in
enhancing
motor
function
people
suffering
from
stroke-related
symptoms
(PSSS).
The
objective
is
determine
most
effective
tDCS-based
approach
and
offer
valuable
evidence
guide
clinical
decision-making.
Methods
included
randomized
controlled
trials
(RCTs)
published
before
September
23,
2024.
We
conducted
a
systematic
search
across
eight
databases:
PubMed,
Embase,
Cochrane
Library,
Web
Science,
China
National
Knowledge
Infrastructure
(CNKI),
Biology
Medicine
(SinoMed),
Wanfang,
VIP.
Network
(NMA)
was
utilizing
R
Studio
Stata
15.0
for
data
analysis.
Results
A
total
74
RCTs
were
this
study,
encompassing
4,335
PSSS
11
intervention
strategies.
NMA
revealed
that
brain-computer
interface
therapy
(BCIT)
combination
tDCS
[surface
under
cumulative
ranking
curve
(SUCRA)
=
88.34%]
improving
Fugl-Meyer
Assessment
Upper
Extremity
score
PSSS.
Mirror
(MT)
(SUCRA
85.96%)
identified
as
optimal
Action
Research
Arm
Test
MT
+
84.29%)
best
Lower
score.
Additionally,
acupuncture
moxibustion
(AM)
77.16%)
increasing
Berg
Balance
Scale
two-dimensional
clustering
analysis
showed
75.83%/85.96%)
strategy
treating
upper
limb
dysfunction
PSSS,
while
AM+tDCS
76.94%/77.16%)
lower
Conclusion
BCIT+tDCS
ability
arm
mobility,
protocol
ability,
balance
ability.
Furthermore,
dysfunction,
whereas
addressing
Future
studies
may
focus
on
investigating
therapeutic
effects
well
AM
score,
order
further
explore
potential
these
two
Systematic
review
registration
https://www.crd.york.ac.uk/PROSPERO/view/CRD42024621998
,
Identifier
PROSPERO
CRD42024621998.
Язык: Английский
Effects of Cerebellar Non-Invasive Stimulation on Neurorehabilitation in Stroke Patients: An Updated Systematic Review
Biomedicines,
Год журнала:
2024,
Номер
12(6), С. 1348 - 1348
Опубликована: Июнь 18, 2024
The
cerebellum
is
emerging
as
a
promising
target
for
noninvasive
brain
stimulation
(NIBS).
A
systematic
review
was
conducted
to
evaluate
the
effects
of
cerebellar
NIBS
on
both
motor
and
other
symptoms
in
stroke
rehabilitation,
its
impact
functional
ability,
potential
side
(PROSPERO
number:
CRD42022365697).
electronic
database
search
performed
by
using
PubMed
Central
(PMC),
EMBASE,
Web
Science,
with
cutoff
date
November
2023.
Data
extracted
included
study
details,
methodology,
outcome
measures,
results.
risk
bias
eligible
studies
also
assessed.
Twenty-two
clinical
involving
1016
participants
were
finally
included,
focus
outcomes
related
post-stroke
recovery
(gait
balance,
muscle
spasticity,
upper
limb
dexterity)
functions
(dysphagia
aphasia).
Positive
observed,
especially
like
gait
balance.
Some
efficiency
observed
dysphagia
rehabilitation.
However,
findings
language
preliminary
inconsistent.
slight
improvement
ability
noted,
no
serious
adverse
reported.
Further
are
needed
explore
non-motor
deficits
understand
how
engagement
can
facilitate
more
precise
treatment
strategies
Язык: Английский
Comparative efficacy and acceptability of non-invasive neuromodulation technologies and botulinum toxin injections for post-stroke spasticity and motor function: a network meta-analysis of randomised controlled trials
EClinicalMedicine,
Год журнала:
2024,
Номер
80, С. 103034 - 103034
Опубликована: Дек. 27, 2024
Язык: Английский