Association of mixed exposure to microplastics with sperm dysfunction: a multi-site study in China
EBioMedicine,
Год журнала:
2024,
Номер
108, С. 105369 - 105369
Опубликована: Сен. 28, 2024
Язык: Английский
Polystyrene microplastics attenuated the impact of perfluorobutanoic acid on Chlorella sorokiniana: Hetero-aggregation, bioavailability, physiology, and transcriptomics
Journal of Hazardous Materials,
Год журнала:
2025,
Номер
488, С. 137344 - 137344
Опубликована: Янв. 25, 2025
Язык: Английский
Drosophila melanogaster as a tractable eco-environmental model to unravel the toxicity of micro- and nanoplastics
Environment International,
Год журнала:
2024,
Номер
192, С. 109012 - 109012
Опубликована: Сен. 17, 2024
Язык: Английский
Polystyrene microplastics (PS-MPs) harness copper presence and promote impairments in early zebrafish (Danio rerio) larvae: developmental, biochemical, transcriptomic approaches and nontargeted metabolomics approaches
Environmental Research,
Год журнала:
2025,
Номер
unknown, С. 121213 - 121213
Опубликована: Фев. 1, 2025
Язык: Английский
Maternal exposure to polystyrene nanoplastics during gestation and lactation caused fertility decline in female mouse offspring
Ecotoxicology and Environmental Safety,
Год журнала:
2025,
Номер
289, С. 117632 - 117632
Опубликована: Янв. 1, 2025
The
impact
of
micro/nano
plastics
(MPs/NPs)
on
human
health
is
a
significant
area
research.
Studies
the
effects
maternal
exposure
to
microplastics
(MPs)
fertility
in
offspring
have
been
conducted,
but
damage
caused
by
nanoplastics
(NPs)
remains
ambiguous.
In
this
study,
pregnant
Kunming
mice
were
exposed
30
mg/kg/day
PS-NPs
from
0.5
gestation
day
(GD)
21
days
postpartum
(dpp).
Increased
rates
miscarriage
and
premature
delivery
observed,
as
well
reduced
litter
size,
indicating
potential
permanent
reproductive
injury
group.
Maternal
impaired
female
offsprings.
Decreased
primordial
increased
growing
follicles
observed
ovaries
at
1
dpp
7
group,
activation
follicles.
This
likely
due
PS-NPs'induction
AKT-FOXO3a
signaling
pathway
downregulating
AMPK
phosphorylation
level
enhancing
mTOR
activity.
Furthermore,
reduction
transzonal
projections
(TZPs)
was
noted
adult
RNA
sequencing
revealed
that
TZPs
related
genes
may
be
linked
CAMKIIβ,
with
corresponding
downregulation
expression
levels.
Overall,
induced
profound
enduring
functions
offspring,
raising
critical
alarms
regarding
multigenerational
toxicity
risks
associated
nanoplastic
mammals.
Язык: Английский
Assessing the Efficacy of Pyrolysis–Gas Chromatography–Mass Spectrometry for Nanoplastic and Microplastic Analysis in Human Blood
Environmental Science & Technology,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 24, 2025
Humans
are
constantly
exposed
to
micro-
and
nanosized
plastics
(MNPs);
however,
there
is
still
limited
understanding
of
their
fate
within
the
body,
partially
due
limitations
with
current
analytical
techniques.
The
study
assessed
appropriateness
pyrolysis–gas
chromatography–mass
spectrometry
(Py-GC-MS)
analysis
for
quantification
a
range
polymers
in
human
blood.
An
extraction
protocol
that
reduced
matrix
interferences
(false
positives)
polyethylene
(PE)
polyvinyl
chloride
(PVC)
was
developed
validated.
Extraction
recoveries
ranged
7–109%,
although
surface-modified
polystyrene
(carboxylated)
increased
nanoparticle
from
17
52%.
Realistic
detection
limits
were
calculated
each
polymer,
accounting
suppression
recovery.
These
up
20
times
higher
than
nominal
Milli-Q
water.
Finally,
method
tested
pilot
Australian
population.
PE
but
present,
no
other
above
limits.
It
concluded
Py-GC-MS
currently
not
suitable
PVC
biological
matrices
presence
nonspecific
pyrolysis
products.
Furthermore,
while
it
plausible
detect
some
blood,
estimated
exposure
concentrations
needed
approaching
technique.
Язык: Английский
Polystyrene microplastics impair brown and beige adipocyte function via the gut microbiota-adipose tissue crosstalk in high-fat diet mice
Journal of Hazardous Materials,
Год журнала:
2025,
Номер
unknown, С. 138225 - 138225
Опубликована: Апрель 1, 2025
Язык: Английский
Advances and Challenges in the Determination of Micro- and Nano-plastics by Pyrolysis-Gas Chromatography-Mass Spectrometry
TrAC Trends in Analytical Chemistry,
Год журнала:
2025,
Номер
unknown, С. 118270 - 118270
Опубликована: Апрель 1, 2025
Язык: Английский
New insights from correlation analysis of microplastics on strawberry surfaces with microplastics in air and pesticides
Journal of Hazardous Materials,
Год журнала:
2025,
Номер
494, С. 138676 - 138676
Опубликована: Май 19, 2025
Язык: Английский
Exploring the potential protective role of anthocyanins in mitigating micro/nanoplastic-induced reproductive toxicity: A steroid receptor perspective
Journal of Pharmaceutical Analysis,
Год журнала:
2024,
Номер
15(2), С. 101148 - 101148
Опубликована: Ноя. 14, 2024
Microplastics
and
nanoplastics
(MPs/NPs)
are
ubiquitous
environmental
pollutants
that
act
as
endocrine-disrupting
chemicals
(EDCs),
raising
significant
concerns
about
their
impact
on
human
health.
Research
highlights
the
hazardous
effects
of
MPs/NPs
both
male
female
reproductive
systems,
influencing
germ
cells,
embryo
development,
progeny.
Additionally,
studies
show
affect
gene
expression
anabolic
steroid
hormones
in
vitro
vivo,
inducing
toxicity
through
mechanisms
such
oxidative
stress
inflammation.
Considering
these
adverse
effects,
identifying
natural
compounds
can
mitigate
is
increasingly
important.
Plants
offer
a
wealth
antioxidants
anti-inflammatory
counteract
harmful
effects.
Among
these,
anthocyanins,
colorants
responsible
for
vibrant
hues
fruits
flowers,
exhibit
wide
range
biological
activities,
including
antioxidant,
anti-inflammatory,
anti-neoplastic
properties.
Moreover,
anthocyanins
modulate
sex
hormone
levels
alleviate
toxicity.
Cyanidin-3-glucoside
(C3G),
one
most
extensively
studied
shows
promise
reducing
toxicity,
particularly
females,
protecting
organs,
testis
epididymis.
This
protective
effect
believed
to
result
from
its
interaction
with
receptors,
specifically
androgen
estrogen
receptors
(ERs).
These
findings
highlight
need
explore
by
which
caused
MPs/NPs.
review
provides
novel
insights
into
how
be
leveraged
lessen
contaminants
health,
especially
concerning
Язык: Английский