Cancers,
Год журнала:
2024,
Номер
16(5), С. 983 - 983
Опубликована: Фев. 28, 2024
This
exploratory
narrative
review
paper
delves
into
the
intricate
interplay
between
per-
and
polyfluoroalkyl
substances
(PFAS)
exposure,
sociodemographic
factors,
influence
of
stressors
in
context
endometrial
cancer.
PFAS,
ubiquitous
environmental
contaminants
notorious
for
their
persistence
ecosystem,
have
garnered
attention
potential
to
disrupt
endocrine
systems
provoke
immune
responses.
We
comprehensively
examine
various
sources
PFAS
encompassing
household
items,
water,
air,
soil,
thus
shedding
light
on
multifaceted
routes
through
which
individuals
encounter
these
compounds.
Furthermore,
we
explore
such
as
income,
education,
occupation,
ethnicity/race,
geographical
location
relationship
cancer
risk.
also
investigated
role
stress
exposure
The
results
revealed
a
significant
impact
factors
both
levels
Stress
emerged
notable
contributing
factor
influencing
development
cancer,
further
emphasizing
importance
management
practices
overall
well-being.
By
synthesizing
evidence
from
diverse
fields,
this
underscores
need
interdisciplinary
research
targeted
interventions
address
complex
stressors,
Plants,
Год журнала:
2023,
Номер
12(3), С. 429 - 429
Опубликована: Янв. 17, 2023
Environmental
contamination
with
a
myriad
of
potentially
toxic
elements
(PTEs)
is
triggered
by
various
natural
and
anthropogenic
activities.
However,
the
industrial
revolution
has
increased
intensity
these
hazardous
their
concentration
in
environment,
which,
turn,
could
provoke
potential
ecological
risks.
Additionally,
most
PTEs
pose
considerable
nuisance
to
human
beings
affect
soil,
aquatic
organisms,
even
nematodes
microbes.
This
comprehensive
review
aims
to:
(i)
introduce
elements;
(ii)
overview
major
sources
environmental
compartments;
(iii)
briefly
highlight
impacts
on
humans,
plants,
life,
health
soil;
(iv)
appraise
methods
for
tackling
PTE-caused
pollution;
(v)
discuss
concept
applications
eco-technological/green
approaches
(comprising
phytoextraction,
rhizofiltration,
phytostabilization,
phytovolatilization,
phytorestoration);
(vi)
role
microbes
phytoremediation
under
PTE
stress;
(vii)
enlighten
genetic
engineering
advancing
varied
PTEs.
Overall,
appropriate
strategies
must
be
developed
order
stop
gene
flow
into
wild
species,
biosafety
issues
properly
addressed.
consistent
efforts
should
undertaken
tackle
(e.g.,
risk
estimation,
understanding,
acceptance
feasibility)
guarantee
successful
implementation
programs,
raise
awareness
this
green
technology
among
laymen,
strengthen
networking
scientists,
stakeholders,
industrialists,
governments
non-government
organizations.
Molecules,
Год журнала:
2023,
Номер
28(15), С. 5689 - 5689
Опубликована: Июль 27, 2023
One
of
the
main
challenges
faced
in
food
safety
is
accumulation
toxic
heavy
metals
from
environmental
sources,
which
can
sequentially
endanger
human
health
when
they
are
consumed.
It
invaluable
to
establish
a
practical
assay
for
determination
safety.
Among
current
detection
methods,
technology
based
on
fluorescent
probes,
with
advantages
sensitivity,
convenience,
accuracy,
cost,
and
reliability,
has
recently
shown
pluralistic
applications
industry,
significant
ensure
Hence,
this
review
systematically
presents
recent
progress
novel
probes
determining
over
past
five
years,
according
fluorophores
newly
emerging
sensing
cores,
could
contribute
broadening
prospects
materials
establishing
more
assays
metal
determinations.
In
brief
Over
the
past
half
century,
world
has
witnessed
an
unprecedented
decline
in
human
fertility
rates.
This
analysis
reviews
various
socioeconomic,
cultural,
and
biological
factors
involved
driving
this
change
considers
whether
low
rates
are
a
temporary
or
permanent
feature
of
our
future
demographic
profile.
Abstract
Since
early
1960s,
spectacular
collapse
fertility.
As
result
phenomenon,
several
countries
already
seeing
their
population
numbers
fall
more
will
follow
coming
decades.
The
causes
involve
complex
interplay
socio-economic,
environmental,
that
have
converged
to
constrain
posterity’s
wake.
large
offspring
no
longer
needed
compensate
for
high
infant
mortality
contemporary
society,
couples
opted
small
families
quality-over-quantity
investment
progeny’s
future.
Simultaneously,
increases
female
education,
enhanced
participation
women
paid
workforce,
resultant
delay
childbearing
placed
limits
on
achievable
family
size.
Progressive
urbanization,
improved
availability
contraceptives,
socio-economic
pressures
experienced
by
young
adults
ageing
societies
also
contributing
fertility’s
demise.
These
factors,
together
with
individualism
pervades
modern
society
increasing
social
acceptability
voluntary
childlessness,
firmly
established
ethos
most
post-transition
countries.
none
these
forces
about
relent,
it
looks
as
if
extremely
might
be
us
some
time
come.
may
long-term
consequences.
lack
selection
pressure
genotypes,
ability
ART
retain
poor
genotypes
within
population,
sustained
exposure
reproductive
toxicants
industrialized
environments
all
contrive
leave
mark
fecundity
species.
This
chapter
delves
into
the
combined
molecular
toxicity
mechanisms
of
heavy
metal
mixtures,
focusing
on
their
pervasive
presence
due
to
industrial
activities
and
impact
human
health.
The
authors
highlight
significance
bioaccumulation
metals
through
ingestion
inhalation,
which
can
lead
various
health
implications.
highlights
multifaceted
effects
mixtures
cardiovascular
system,
contributing
diseases
like
atherosclerosis
hypertension
oxidative
stress
vascular
inflammation.
It
details
interactions
these
with
proteins,
particularly
inhibition
ATPases
promotion
damage,
leading
dysfunction.
briefly
touches
upon
link
between
cadmium
exposure
prostate
cancer,
emphasizing
need
for
further
investigation
underlying
this
association.
Additionally,
it
mentions
potential
zinc
sulfate
olfactory
neuron
subtypes
in
adult
fish,
suggesting
that
disrupt
sensory
systems
aquatic
organisms.
Moreover,
explores
neurotoxicity
metals,
discussing
nervous
system
neurodevelopmental
disorders.
also
examines
male
female
reproductive
systems,
evidence
disruptions
hormone
levels,
sperm
quality,
fertility.
call
enhanced
monitoring
levels
general
population
better
understand
its
They
emphasize
research
by
contribute
health,
inform
clinical
treatments
public
interventions.
By
highlighting
bioaccumulation,
stress,
time-dependent
responses,
study
sheds
light
urgent
intervention
strategies
mitigate
adverse
environment.
International Journal of Phytoremediation,
Год журнала:
2025,
Номер
unknown, С. 1 - 20
Опубликована: Фев. 6, 2025
Cadmium
(Cd)
is
one
of
the
most
harmful
heavy
metals
in
environment,
negatively
impacting
plant
growth
and
development.
However,
phytoremediation
which
an
environmentally
friendly
cost-effective
technique
can
be
used
to
treat
Cd
contaminated
environments.
It
effectively
removes
from
polluted
soil
water
through
processes,
such
as
phytoextraction,
phytostabilization,
phytostimulation,
phytofiltration,
phytotransformation.
Numerous
research
has
shown
evidences
that
biological,
physical,
chemical,
agronomic,
genetic
methods
are
being
utilized
improve
phytoremediation.
A
special
group
plants
known
hyperaccumulator
further
enhance
removal,
turning
areas
into
productive
land.
These
accumulate
root
cell
vacuoles
aerial
parts.
Despite
morphological
variations,
different
species
remediate
at
rates
using
either
or
multiple
mechanisms.
To
effectiveness
phytoremediation,
it
essential
thoroughly
understand
mechanisms
control
accumulation
persistence
plants,
including
absorption,
translocation,
elimination
processes.
what
missing
understanding
depth
idea
on
how
limitations
overcome.
The
addressed
various
strategies,
natural
chemical
amendments,
engineering,
microbial
stimulation,
broadly
categorized
amelioration
capacity
enhancement
approaches.
This
review
presents
a
concise
overview
latest
employed
this
process.
Moreover,
also
underscores
creditability
pollution
offers
promising
approach
for
eliminating
sites
restoring
their
productivity.
Additionally,
we
recommend
directing
future
toward
enhancing
biochemical
capabilities
remediation
purposes,
elucidating
molecular
underlying
damage
caused
by
fundamental
principles
regulating
enrichment
plants.
RSC Advances,
Год журнала:
2025,
Номер
15(6), С. 4236 - 4249
Опубликована: Янв. 1, 2025
A
reversible
fluorescent-colorimetric
novel
mono-Schiff
base
receptor
for
the
detection
of
Pb
2+
in
aqueous
medium
has
been
developed.
When
exposed
to
,
L
exhibits
a
very
good
selective
fast
on–off
response.
Diagnostics,
Год журнала:
2025,
Номер
15(5), С. 581 - 581
Опубликована: Фев. 27, 2025
Carbon
monoxide
(CO)
poisoning
is
a
significant
public
health
issue,
with
diagnosis
often
complicated
by
non-specific
symptoms
and
limited
access
to
specialised
tools.
Early
detection
vital
for
preventing
long-term
complications.
The
review
examines
diagnostic
challenges,
prognostic
factors,
management
strategies,
future
advancements
in
CO
poisoning.
It
highlights
the
limitations
of
current
techniques
such
as
blood
carboxyhaemoglobin
levels
pulse
CO-oximetry,
while
exploring
emerging
methods
rapid
detection.
Prognosis
influenced
exposure
severity
delayed
treatment,
which
increases
risk
neurological
damage.
Hyperbaric
oxygen
therapy
(HBOT)
remains
primary
treatment
but
not
always
accessible.
Advances
portable
CO-oximeters
biomarkers
offer
potential
improved
early
monitoring.
Addressing
resource
refining
protocols
are
crucial
better
patient
outcomes.
Future
research
should
focus
on
personalised
strategies
integration
modern
technologies
enhance
care.
Frontiers in Nutrition,
Год журнала:
2023,
Номер
10
Опубликована: Март 14, 2023
Congenital
heart
defects
(CHDs)
are
congenital
abnormalities
involving
the
gross
structures
of
and
large
blood
vessels.
Environmental
factors,
genetic
factors
their
interactions
may
contribute
to
pathogenesis
CHDs.
Generally,
trace
elements
can
be
classified
into
essential
non-essential
elements.
Essential
such
as
copper
(Cu),
zinc
(Zn),
iron
(Fe),
selenium
(Se),
manganese
(Mn)
play
important
roles
in
human
biological
functions
metabolic
function,
oxidative
stress
regulation,
embryonic
development.
Non-essential
cadmium
(Cd),
arsenic
(As),
lead
(Pb),
nickle
(Ni),
barium
(Ba),
chromium
(Cr)
mercury
(Hg)
harmful
health
even
at
low
concentrations.
Recent
studies
have
revealed
potential
involvement
these
In
this
review,
we
summarized
current
exploring
exposure
risks
CHDs,
order
provide
further
insights
for
prevention
Journal of Toxicology and Environmental Health Part B,
Год журнала:
2023,
Номер
26(7), С. 371 - 386
Опубликована: Июнь 12, 2023
This
review
is
based
upon
evidence
from
the
published
effects
of
green
tea
polyphenols
(GTP)
on
genotoxic
damage
induced
by
metals
with
carcinogenic
potential.
First,
relationship
between
GTP
and
antioxidant
defense
system
provided.
Subsequently,
processes
involved
in
oxidative
stress
generated
their
to
DNA
examined.
The
demonstrated
that
generally
decrease
exposure
such
as
arsenic
(As),
cadmium
(Cd),
cobalt
(Co),
copper
(Cu),
chromium
(Cr),
iron
(Fe),
lead
(Pb).
pathways
these
are
related
to:
(1)
direct
scavenging
free
radicals
(FR);
(2)
activation
mechanisms
repair
damage;
(3)
regulation
endogenous
system;
(4)
elimination
cells
genetic
via
apoptosis.
results
obtained
studies
reviewed
demonstrate
potential
for
possible
use
prevent
treat
populations
exposed
metals.
Further,
may
be
considered
adjuvants
treatments
metal-associated
diseases
damage.
