Association between heavy metal exposure and bacterial vaginosis: A cross-sectional study DOI Creative Commons

Yu-Xue Feng,

Ming-Zhi Tan,

Hu Qiu

et al.

PLoS ONE, Journal Year: 2025, Volume and Issue: 20(1), P. e0316927 - e0316927

Published: Jan. 8, 2025

Bacterial vaginosis (BV) is a prevalent cause of vaginal symptoms in women reproductive age. With the widespread heavy metal pollutants and their harmful function on women’s immune hormonal systems, it necessary to explore association between exposure BV. This study investigates potential relationship serum metals bacterial cohort American women. The present employed cross-sectional analysis 2,493 participating 2001–2004 National Health Nutrition Examination Survey (NHANES). Multivariable logistic regression models were utilized assess correlation these variables. A stratified was performed investigate among different population groups further, smooth curve fittings conducted intuitively evaluate correlation. According current results, significant identified high levels lead cadmium likelihood developing vaginosis. We found that (OR = 1.35, 95% CI: 1.06–1.72, p 0.016) 1.41, 1.01–1.98, 0.047) increased risk by 35% 41%, respectively, highest level group comparison lowest fully adjusted model. Furthermore, research discovered no statistically total mercury heightened susceptibility 0.96, 0.75–1.23, 0.763). Results our indicated an inverse risk, including cadmium. Reducing could be vital preventing managing

Language: Английский

Remediating contaminated environmental systems: the role of plants in cadmium removal DOI

Asanka Tennakoon,

Harshana Galahitigama,

Sameera R. Samarakoon

et al.

International Journal of Phytoremediation, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 20

Published: Feb. 6, 2025

Cadmium (Cd) is one of the most harmful heavy metals in environment, negatively impacting plant growth and development. However, phytoremediation which an environmentally friendly cost-effective technique can be used to treat Cd contaminated environments. It effectively removes from polluted soil water through processes, such as phytoextraction, phytostabilization, phytostimulation, phytofiltration, phytotransformation. Numerous research has shown evidences that biological, physical, chemical, agronomic, genetic methods are being utilized improve phytoremediation. A special group plants known hyperaccumulator further enhance removal, turning areas into productive land. These accumulate root cell vacuoles aerial parts. Despite morphological variations, different species remediate at rates using either or multiple mechanisms. To effectiveness phytoremediation, it essential thoroughly understand mechanisms control accumulation persistence plants, including absorption, translocation, elimination processes. what missing understanding depth idea on how limitations overcome. The addressed various strategies, natural chemical amendments, engineering, microbial stimulation, broadly categorized amelioration capacity enhancement approaches. This review presents a concise overview latest employed this process. Moreover, also underscores creditability pollution offers promising approach for eliminating sites restoring their productivity. Additionally, we recommend directing future toward enhancing biochemical capabilities remediation purposes, elucidating molecular underlying damage caused by fundamental principles regulating enrichment plants.

Language: Английский

Citations

1
The large-scale period of atmospheric trace metal deposition to urban landscape trees as a biomonitor DOI
Kaan Işınkaralar

Biomass Conversion and Biorefinery, Journal Year: 2022, Volume and Issue: 14(5), P. 6455 - 6464

Published: May 14, 2022

Language: Английский

Citations

38
Recent Progress on Fluorescent Probes in Heavy Metal Determinations for Food Safety: A Review DOI Creative Commons

Liqing Lai,

Yan Fang, Geng Chen

et al.

Molecules, Journal Year: 2023, Volume and Issue: 28(15), P. 5689 - 5689

Published: July 27, 2023

One of the main challenges faced in food safety is accumulation toxic heavy metals from environmental sources, which can sequentially endanger human health when they are consumed. It invaluable to establish a practical assay for determination safety. Among current detection methods, technology based on fluorescent probes, with advantages sensitivity, convenience, accuracy, cost, and reliability, has recently shown pluralistic applications industry, significant ensure Hence, this review systematically presents recent progress novel probes determining over past five years, according fluorophores newly emerging sensing cores, could contribute broadening prospects materials establishing more assays metal determinations.

Language: Английский

Citations

18
Population decline: where demography, social science and biology intersect DOI Creative Commons
R. John Aitken

Reproduction, Journal Year: 2024, Volume and Issue: 168(1)

Published: April 5, 2024

In brief Over the past half century, world has witnessed an unprecedented decline in human fertility rates. This analysis reviews various socioeconomic, cultural, and biological factors involved driving this change considers whether low rates are a temporary or permanent feature of our future demographic profile. Abstract Since early 1960s, spectacular collapse fertility. As result phenomenon, several countries already seeing their population numbers fall more will follow coming decades. The causes involve complex interplay socio-economic, environmental, that have converged to constrain posterity’s wake. large offspring no longer needed compensate for high infant mortality contemporary society, couples opted small families quality-over-quantity investment progeny’s future. Simultaneously, increases female education, enhanced participation women paid workforce, resultant delay childbearing placed limits on achievable family size. Progressive urbanization, improved availability contraceptives, socio-economic pressures experienced by young adults ageing societies also contributing fertility’s demise. These factors, together with individualism pervades modern society increasing social acceptability voluntary childlessness, firmly established ethos most post-transition countries. none these forces about relent, it looks as if extremely might be us some time come. may long-term consequences. lack selection pressure genotypes, ability ART retain poor genotypes within population, sustained exposure reproductive toxicants industrialized environments all contrive leave mark fecundity species.

Language: Английский

Citations

7
Maternal exposure to heavy metals and risk for severe congenital heart defects in offspring DOI
Chengrong Wang, Xin Pi, Shengju Yin

et al.

Environmental Research, Journal Year: 2022, Volume and Issue: 212, P. 113432 - 113432

Published: May 6, 2022

Language: Английский

Citations

28
Exposure to essential and non-essential trace elements and risks of congenital heart defects: A narrative review DOI Creative Commons
Yipu Liang, Zijian Pan,

Zhu Mingzheng

et al.

Frontiers in Nutrition, Journal Year: 2023, Volume and Issue: 10

Published: March 14, 2023

Congenital heart defects (CHDs) are congenital abnormalities involving the gross structures of and large blood vessels. Environmental factors, genetic factors their interactions may contribute to pathogenesis CHDs. Generally, trace elements can be classified into essential non-essential elements. Essential such as copper (Cu), zinc (Zn), iron (Fe), selenium (Se), manganese (Mn) play important roles in human biological functions metabolic function, oxidative stress regulation, embryonic development. Non-essential cadmium (Cd), arsenic (As), lead (Pb), nickle (Ni), barium (Ba), chromium (Cr) mercury (Hg) harmful health even at low concentrations. Recent studies have revealed potential involvement these In this review, we summarized current exploring exposure risks CHDs, order provide further insights for prevention

Language: Английский

Citations

16
Associations between multiple metal exposure and fertility in women: A nested case-control study DOI Creative Commons
Xiang Hong, Wei Wang, Lingling Huang

et al.

Ecotoxicology and Environmental Safety, Journal Year: 2024, Volume and Issue: 272, P. 116030 - 116030

Published: Feb. 3, 2024

Metal pollution can cause a decline in female fertility, however, previous studies have focused more on the effect of single metal fertility. In this study, we evaluated mixtures fertility based nested case-control samples. The plasma levels 22 elements from 180 women were determined by an inductively coupled mass spectrometer (ICP-MS). Minimum absolute contraction and selection operator (LASSO) penalty regression selected metals with greatest influence clinical outcome. Logistic was used to analyze correlation between while Bayesian kernel function (BKMR) model mixed metals. Eight (Calcium (Ca), Chromium (Cr), Cobalt (Co), Copper (Cu), Zinc (Zn), Rubidium (Rb), Strontium (Sr) Zirconium (Zr)) LASSO for subsequent analysis. After adjusting covariates, logistic showed that Cu (Odds Ratio(OR):0.33, 95% CI: 0.13 − 0.84) Co (OR:0.38, 0.15 −0.94) caused significant reduction identified protective Zn (OR: 2.96, CI:1.21 −7.50) Trend tests increased Cr, Cu, Rb associated reduced BKMR Co, had nonlinear relationship when controlling concentrations other suggested Cr might exert Analysis negative Rb, positive Furthermore, found evidence interaction Cr. Our findings require further validation may identify new mechanisms future.

Language: Английский

Citations

5
Exploring the Potential Link between PFAS Exposure and Endometrial Cancer: A Review of Environmental and Sociodemographic Factors DOI Open Access
A. E. Ayodele, Emmanuel Obeng-Gyasi

Cancers, Journal Year: 2024, Volume and Issue: 16(5), P. 983 - 983

Published: Feb. 28, 2024

This exploratory narrative review paper delves into the intricate interplay between per- and polyfluoroalkyl substances (PFAS) exposure, sociodemographic factors, influence of stressors in context endometrial cancer. PFAS, ubiquitous environmental contaminants notorious for their persistence ecosystem, have garnered attention potential to disrupt endocrine systems provoke immune responses. We comprehensively examine various sources PFAS encompassing household items, water, air, soil, thus shedding light on multifaceted routes through which individuals encounter these compounds. Furthermore, we explore such as income, education, occupation, ethnicity/race, geographical location relationship cancer risk. also investigated role stress exposure The results revealed a significant impact factors both levels Stress emerged notable contributing factor influencing development cancer, further emphasizing importance management practices overall well-being. By synthesizing evidence from diverse fields, this underscores need interdisciplinary research targeted interventions address complex stressors,

Language: Английский

Citations

5
Toxoplasma gondii infection and testosterone alteration: A systematic review and meta-analyses DOI Creative Commons
Amir Abdoli, Fatemeh Ghaffarifar, Zohreh Sharifi

et al.

PLoS ONE, Journal Year: 2024, Volume and Issue: 19(4), P. e0297362 - e0297362

Published: April 3, 2024

Background Toxoplasma gondii ( T . ) is a worldwide distributed protozoan parasite which has infected wide range of warm-blooded animals and humans. The most common form infection asymptomatic (latent); nevertheless, latent toxoplasmosis can induce various alterations sex hormones, especially testosterone, in humans animals. On the other hand, testosterone involved behavioral traits reproductive functions both sexes. Hence, purpose this systematic review to summarize available evidence regarding association between alteration. Methods In setting review, an electronic search (any date 10 January 2023) without language restrictions was performed using Science Direct, Web Science, PubMed, Scopus, Google Scholar. PRISMA guidelines were followed. Following initial search, total 12,306 titles abstracts screened initially; 12,281 excluded due lack eligibility criteria or duplication. Finally, 24 articles met included criteria. A mean±standard deviation (SD) calculated assess difference positive negative possibility publication bias assessed Egger’s regression. P -value < 0.05 considered statistically significant. Results This identified (18 studies six animals). Most human (13 out 19) reported increased level following males, while three decreased levels two insignificant change. Eleven (seven datasets males seven females) eligible be data synthesis. Based on random-effects model, pooled mean± SD than by 0.73 0.55 units females, respectively. regression did not detect significant females p = value 0.95 0.71), Three male (rats, mice, spotted hyenas) female (mice decline compared with non-infected While, one study rats no changes Moreover, Conclusions provides new insights about alteration identifies relevant gaps that inform encourage further studies. consequence could partly associated sexual behavior transmission parasite. declining may impairments, observed -infected Furthermore, these findings suggest great need for more epidemiological experimental investigations depth understand relationship alongside future consequences

Language: Английский

Citations

5
Effects of green tea polyphenols against metal-induced genotoxic damage: underlying mechanistic pathways DOI
María del Carmen García‐Rodríguez, Lourdes Montserrat Hernández‐Cortés, Vı́ctor Manuel Mendoza-Núñez

et al.

Journal of Toxicology and Environmental Health Part B, Journal Year: 2023, Volume and Issue: 26(7), P. 371 - 386

Published: June 12, 2023

This review is based upon evidence from the published effects of green tea polyphenols (GTP) on genotoxic damage induced by metals with carcinogenic potential. First, relationship between GTP and antioxidant defense system provided. Subsequently, processes involved in oxidative stress generated their to DNA examined. The demonstrated that generally decrease exposure such as arsenic (As), cadmium (Cd), cobalt (Co), copper (Cu), chromium (Cr), iron (Fe), lead (Pb). pathways these are related to: (1) direct scavenging free radicals (FR); (2) activation mechanisms repair damage; (3) regulation endogenous system; (4) elimination cells genetic via apoptosis. results obtained studies reviewed demonstrate potential for possible use prevent treat populations exposed metals. Further, may be considered adjuvants treatments metal-associated diseases damage.

Language: Английский

Citations

13