Sleep Epidemiology,
Год журнала:
2022,
Номер
2, С. 100022 - 100022
Опубликована: Янв. 19, 2022
Habitual
insufficient
sleep
may
contribute
to
cardiometabolic
disease
in
the
United
States,
particularly
among
racial
and
ethnic
minorities.
However,
there
is
mixed
evidence
on
secular
trends
U.S.
duration.
Cross-sectional
data
from
413,417
individuals
were
acquired
National
Health
Interview
Survey
2005–2018.
Variables
included
self-reported
duration
as
well
lifetime
diagnosis
of
hypertension,
coronary
heart
disease,
diabetes,
pre-diabetes,
obesity.
Population-weighted
robust
Poisson
models
estimated
annual
prevalence
risk
ratios
(PRR)
a
function
Population-based
survey.
Daily
decreased
-0.62
min
([-0.71,
0.54],
p
<
0.01)
annually
this
decline
began
only
after
2010,
when
fell
by
1.04
([-1.21,
-0.86],
each
year.
This
trend
varied
race
(two-way
ANOVA,
=
0.02),
such
that
Mexican
Hispanic
saw
greater
(-1.83
[-2.37,
-1.30]
per
year,
than
whites
(-0.83
[-1.02,
-0.64]
0.01).
Additionally,
1-h
loss
daily
was
linked
4%
hypertension
(PRR:
1.04,
[1.04,
1.05]),
3%
diabetes
1.03
[1.01,
8%
obesity
1.08
[1.07,
1.09])
adjusting
for
age,
sex,
employment,
marital
status,
survey
There
individuals.
Moreover,
reduced
associated
with
more
prevalent
disease.
In
2010,
the
American
Heart
Association
defined
a
novel
construct
of
cardiovascular
health
to
promote
paradigm
shift
from
focus
solely
on
disease
treatment
one
inclusive
positive
promotion
and
preservation
across
life
course
in
populations
individuals.
Extensive
subsequent
evidence
has
provided
insights
into
strengths
limitations
original
approach
defining
quantifying
health.
response,
convened
writing
group
recommend
enhancements
updates.
The
definition
quantification
each
metrics
(Life’s
Simple
7)
were
evaluated
for
responsiveness
interindividual
variation
intraindividual
change.
New
considered,
age
spectrum
was
expanded
include
entire
course.
foundational
contexts
social
determinants
psychological
addressed
as
crucial
factors
optimizing
preserving
This
presidential
advisory
introduces
an
enhanced
assessing
health:
Life’s
Essential
8.
components
8
diet
(updated),
physical
activity,
nicotine
exposure
sleep
(new),
body
mass
index,
blood
lipids
glucose
pressure.
Each
metric
new
scoring
algorithm
ranging
0
100
points,
allowing
generation
composite
score
(the
unweighted
average
all
components)
that
also
varies
points.
Methods
implementing
assessment
longitudinal
monitoring
are
discussed,
potential
data
sources
tools
widespread
adoption
policy,
public
health,
clinical,
institutional,
community
settings.
British Journal of Sports Medicine,
Год журнала:
2019,
Номер
53(11), С. 667 - 699
Опубликована: Май 16, 2019
Mental
health
symptoms
and
disorders
are
common
among
elite
athletes,
may
have
sport
related
manifestations
within
this
population
impair
performance.
cannot
be
separated
from
physical
health,
as
evidenced
by
mental
increasing
the
risk
of
injury
delaying
subsequent
recovery.
There
no
evidence
or
consensus
based
guidelines
for
diagnosis
management
in
athletes.
Diagnosis
must
differentiate
character
traits
particular
to
athletes
psychosocial
maladaptations.Management
strategies
should
address
all
contributors
consider
biopsychosocial
factors
relevant
maximise
benefit
minimise
harm.
Management
involve
both
treatment
affected
individual
optimising
environments
which
train
compete.
To
advance
a
more
standardised,
approach
an
International
Olympic
Committee
Consensus
Work
Group
critically
evaluated
current
state
science
provided
recommendations.
Medicine & Science in Sports & Exercise,
Год журнала:
2018,
Номер
51(3), С. 454 - 464
Опубликована: Окт. 18, 2018
ABSTRACT
The
physiologic
mechanisms
by
which
the
four
activities
of
sleep,
sedentary
behavior,
light-intensity
physical
activity,
and
moderate-to-vigorous
activity
(MVPA)
affect
health
are
related,
but
these
relationships
have
not
been
well
explored
in
adults.
Research
studies
commonly
evaluated
how
time
spent
one
affects
health.
Because
can
only
increase
decreasing
another,
such
cannot
determine
extent
that
a
benefit
is
due
to
versus
reallocating
among
other
activities.
For
example,
interventions
improve
sleep
possibly
also
MVPA.
If
so,
overall
effect
on
risk
premature
mortality
both
more
MVPA
better
sleep.
Further,
potential
for
interaction
between
outcomes
largely
unexplored.
there
threshold
minutes
per
day,
above
adverse
effects
behavior
eliminated?
This
article
considers
24-h
Activity
Cycle
(24-HAC)
model
as
paradigm
exploring
inter-relatedness
It
discusses
measure
each
activities,
analytical
statistical
challenges
analyzing
data
based
model,
including
inevitable
challenge
confounding
usefulness
this
described
reviewing
selected
research
findings
aided
creation
discussing
future
applications
24-HAC
model.
Diabetes Care,
Год журнала:
2022,
Номер
46(1), С. 101 - 110
Опубликована: Ноя. 16, 2022
OBJECTIVE
People
with
type
2
diabetes
may
have
insufficient
or
prolonged
sleep
that
could
accelerate
cardiovascular
disease
(CVD)
onset,
but
existing
evidence
from
prospective
studies
has
been
limited.
We
examined
the
association
of
duration
CVD
incidence
and
mortality
in
this
high-risk
population.
RESEARCH
DESIGN
AND
METHODS
This
study
included
18,876
participants
UK
Biobank
who
were
free
cancer
at
baseline.
Habitual
was
obtained
using
a
baseline
questionnaire.
Cox
proportional
hazards
regression
models
used
to
examine
between
events.
RESULTS
During
an
average
follow-up
11.0–12.0
years,
we
documented
2,570
incident
cases
atherosclerotic
(ASCVD)
598
deaths.
Compared
sleeping
for
7
h/day,
multivariable-adjusted
hazard
ratios
≤5
≥10
h/day
1.26
(95%
CI
1.08,
1.48)
1.41
(1.16,
1.70)
ASCVD,
1.22
(0.99,
1.50)
1.16
(0.88,
1.52)
coronary
artery
disease,
1.70
(1.23,
2.35)
2.08
(1.44,
3.01)
ischemic
stroke,
1.02
(0.72,
1.44)
1.45
(1.01,
2.10)
peripheral
1.42
(1.02,
1.97)
1.85
(1.30,
2.64)
mortality.
Similar
results
observed
most
sensitivity
analyses
aimed
address
potential
reverse
causation
joint
metabolic
control
severity
status.
CONCLUSIONS
Short
long
durations
independently
associated
increased
risks
onset
death
among
people
diabetes.
The Journal of Physiology,
Год журнала:
2017,
Номер
595(12), С. 3691 - 3700
Опубликована: Март 10, 2017
The
soaring
prevalence
of
obesity
and
diabetes
is
associated
with
an
increase
in
comorbidities,
including
elevated
risk
for
cardiovascular
diseases
(CVDs).
CVDs
continue
to
be
among
the
leading
causes
death
disability
United
States.
While
increased
nutritional
intake
from
energy-dense
diet
known
disrupt
metabolic
homeostasis
contributes
disease
risk,
circadian
rhythm
disruption
emerging
as
a
new
factor
CVD.
Circadian
rhythms
coordinate
health
via
temporal
control
organismal
metabolism
physiology.
Thus,
interventions
that
improve
are
prospective
entry
points
mitigate
cardiometabolic
risk.
Although
light
strong
modulator
neural
clock,
time
food
dominant
agent
affects
clocks
organs.
We
discovered
imposing
time-restricted
feeding
(TRF)
regimen
which
all
caloric
intakes
occur
consistently
within
≤
12
h
every
day
exerts
many
benefits.
TRF
prevents
excessive
body
weight
gain,
improves
sleep,
attenuates
age-
diet-induced
deterioration
cardiac
performance.
Using
integrative
approach
combines
Drosophila
melanogaster
(fruit
fly)
genetics
transcriptome
analyses
it
was
found
beneficial
effects
mediated
by
ATP-dependent
TCP/TRiC/CCT
chaperonin
mitochondrial
electron
transport
chain
components.
Parallel
studies
rodents
have
shown
reduces
risks
maintaining
homeostasis.
As
modern
humans
live
under
extended
periods
wakefulness
ingestion
events,
daily
eating
pattern
offers
potential
target
lifestyle
intervention
reduce
CVD
Antioxidants,
Год журнала:
2020,
Номер
9(2), С. 107 - 107
Опубликована: Янв. 26, 2020
Post-traumatic
stress
disorder
(PTSD)
is
a
chronic
condition
characterized
by
symptoms
of
physiological
and
psychosocial
burden.
While
growing
research
demonstrated
signs
inflammation
in
PTSD,
specific
biomarkers
that
may
be
representative
PTSD
such
as
the
detailed
neural
correlates
underlying
inflammatory
responses
relation
to
trauma
exposure
are
seldom
discussed.
Here,
we
review
recent
studies
explored
alterations
key
markers
well
neuroimaging-based
further
investigated
within
brain
provide
comprehensive
summary
literature
with
neurological
perspective.
A
search
was
conducted
on
published
from
2009
through
2019
PubMed
Web
Science.
Fifty
original
articles
were
selected.
Major
findings
included
elevated
levels
serum
proinflammatory
cytokines
individuals
across
various
types,
compared
those
without
PTSD.
Furthermore,
altered
associated
structural
functional
regions
responsible
for
regulation
emotion,
including
amygdala,
hippocampus,
frontal
cortex.
Future
utilize
both
central
peripheral
warranted
elucidate
pathway
pathophysiology
Current Opinion in Pulmonary Medicine,
Год журнала:
2019,
Номер
25(6), С. 578 - 593
Опубликована: Сен. 15, 2019
Purpose
of
review
This
provides
a
contemporary
sleep
apnea
with
emphasis
on
definitions,
epidemiology,
and
consequences.
Recent
findings
Amyloid
β-42
is
one
the
main
peptides
forming
amyloid
plaques
in
brains
Alzheimer
patients.
Poorer
quality
shorter
duration
have
been
associated
higher
burden.
Decreased
time
elderly
precipitating
factor
retention.
Studies
shown
that
dysregulation
homeostatic
balance
major
inhibitory
excitatory
amino
acid
neurotransmitter
systems
gamma-aminobutyric
(GABA)
glutamate
play
role
disordered
breathing
(SDB).
Summary
Untreated
(obstructive
and/or
central
apnea)
are
an
important
cause
medical
mortality
morbidity.
OSA
characterized
by
recurrent
episodes
partial
or
complete
collapse
upper
airway
during
followed
hypoxia
sympathetic
activation.
Apneic
events
terminated
arousal,
increases
pulse
blood
pressure,
re-oxygenation
release
inflammatory
factors.
Individuals
increased
risk
developing
atrial
fibrillation.
Hypoxemia
poor
because
increase
cognitive
decline
elderly.
JAMA Network Open,
Год журнала:
2023,
Номер
6(12), С. e2346006 - e2346006
Опубликована: Дек. 4, 2023
Importance
Sleep
disturbances
and
clinical
sleep
disorders
are
associated
with
all-cause
dementia
neurodegenerative
conditions,
but
it
remains
unclear
how
longitudinal
changes
in
impact
the
incidence
of
cognitive
impairment.
Objective
To
evaluate
association
patterns
age-related
function
healthy
older
adults.
Design,
Setting,
Participants
This
cross-sectional
study
is
a
retrospective
analyses
Seattle
Longitudinal
Study
(SLS),
which
evaluated
self-reported
duration
(1993-2012)
performance
(1997-2020)
within
SLS
were
enrolled
as
part
community-based
cohort
from
Group
Health
Cooperative
Puget
Sound
Maintenance
Organization
Washington
between
1956
2020.
Data
analysis
was
performed
September
2020
to
May
2023.
Main
Outcomes
Measures
The
main
outcome
for
this
impairment,
defined
by
subthreshold
on
both
Mini-Mental
State
Examination
Mattis
Dementia
Rating
Scale.
self-report
median
nightly
over
last
week
assessed
longitudinally
multiple
time
points.
Median
duration,
phenotype
(short
sleep,
≤7
hours;
medium
=
7
hour;
long
≥7
hours),
change
(slope),
variability
(SD
or
variability)
evaluated.
Results
Of
participants
SLS,
only
1104
who
administered
Behavior
Questionnaire
neuropsychologic
battery
included
study.
A
total
826
individuals
(mean
[SD]
age,
76.3
[11.8]
years;
468
women
[56.7%];
217
apolipoprotein
E
ε4
allele
carriers
[26.3%])
had
complete
demographic
information
Analysis
using
Cox
proportional
hazard
regression
model
(concordance,
0.76)
showed
that
status
short
sleeper
(hazard
ratio,
3.67;
95%
CI,
1.59-8.50)
higher
3.06;
1.14-5.49)
significantly
Conclusions
Relevance
In
performance,
impaired
performance.
Furthermore,
high
highlighting
possibility
instability
periods
may
decline