Insomnia, fatigue and psychosocial well‐being during COVID‐19 pandemic: A cross‐sectional survey of hospital nursing staff in the United States

Journal of Clinical Nursing, Год журнала: 2020, Номер 32(15-16), С. 5382 - 5395

Опубликована: Ноя. 21, 2020

To describe the levels of insomnia, fatigue and intershift recovery, psychological well-being (burnout, post-traumatic stress distress), to examine differences in these measures based on work-related characteristics among nursing staff during COVID-19 pandemic United States.The has created a major physical burden States worldwide. A better understanding conditions will lead tailored support resources for after pandemic.Cross-sectional study.Hospital nurses assistants (N = 587) were recruited online between May-June 2020. The survey included insomnia (Insomnia Severity Index) recovery (Occupational Fatigue Exhaustion Recovery-15), burnout (Maslach Burnout Inventory-Human Services Survey), (Short Post-Traumatic Stress Disorder Rating Interview) distress (Patient Health Questionnaire-4), questions work demographics. STROBE checklist was followed reporting.The sample had subthreshold moderate-to-high chronic fatigue, high acute low-to-moderate recovery. experienced increased emotional exhaustion depersonalisation, personal accomplishment, moderate stress. Nurses who cared patients significantly scored worse almost all than their co-workers. Certain factors such as working hours per week frequency 30-min breaks significant.Nursing poor sleep, multiple problems pandemic. Moreover, involved care patients, worked more 40 h skipped showed generally self-reported outcomes.Nursing administration is recommended monitor units, re-visit current scheduling practices, reinforce rest provide access mental health sleep wellness with additional front-line groups.

Язык: Английский

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The Psychedelic Future of Post-Traumatic Stress Disorder Treatment

Current Neuropharmacology, Год журнала: 2024, Номер 22(4), С. 636 - 735

Опубликована: Янв. 5, 2024

Post-traumatic stress disorder (PTSD) is a mental health condition that can occur following exposure to traumatic experience. An estimated 12 million U.S. adults are presently affected by this disorder. Current treatments include psychological therapies (e.g., exposure-based interventions) and pharmacological selective serotonin reuptake inhibitors (SSRIs)). However, significant proportion of patients receiving standard-of-care for PTSD remain symptomatic, new approaches other trauma-related conditions greatly needed. Psychedelic compounds alter cognition, perception, mood currently being examined their efficacy in treating despite current status as Drug Enforcement Administration (DEA)- scheduled substances. Initial clinical trials have demonstrated the potential value psychedelicassisted therapy treat psychiatric disorders. In comprehensive review, we summarize state science care, including shortcomings. We review studies psychedelic interventions PTSD, disorders, common comorbidities. The classic psychedelics psilocybin, lysergic acid diethylamide (LSD), N,N-dimethyltryptamine (DMT) DMT-containing ayahuasca, well entactogen 3,4-methylenedioxymethamphetamine (MDMA) dissociative anesthetic ketamine, reviewed. For each drug, present history use, somatic effects, pharmacology, safety profile. rationale proposed mechanisms use traumarelated disorders discussed. This concludes with an in-depth consideration future directions applications maximize therapeutic benefit minimize risk individuals communities impacted conditions.

Язык: Английский

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Posttraumatic Stress Disorder and Inflammation: Untangling Issues of Bidirectionality

Biological Psychiatry, Год журнала: 2019, Номер 87(10), С. 885 - 897

Опубликована: Ноя. 14, 2019

Язык: Английский

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Guided, internet based, cognitive behavioural therapy for post-traumatic stress disorder: pragmatic, multicentre, randomised controlled non-inferiority trial (RAPID)

BMJ, Год журнала: 2022, Номер unknown, С. e069405 - e069405

Опубликована: Июнь 16, 2022

To determine if guided internet based cognitive behavioural therapy with a trauma focus (CBT-TF) is non-inferior to individual face-to-face CBT-TF for mild moderate post-traumatic stress disorder (PTSD) one traumatic event.

Язык: Английский

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Neurophysiology and Psychopathology Underlying PTSD and Recent Insights into the PTSD Therapies—A Comprehensive Review

Journal of Clinical Medicine, Год журнала: 2020, Номер 9(9), С. 2951 - 2951

Опубликована: Сен. 12, 2020

Post-traumatic stress disorder (PTSD) is a well-known psychiatric that affects millions of people worldwide. Pharmacodynamic and cognitive-behavioral therapies (CBT) have been used to treat patients with PTSD. However, it remains unclear whether there are concurrent changes in psychopathological neurophysiological factors associated PTSD patients. Past reports described those efficient fatty acid metabolism, neurogenesis, mitochondrial energy balance could improve ability cope against the conditioned fear responses traumatic memories. Furthermore, cognitive, behavioral, cellular, molecular evidence can be combined create personalized for sufferers either or without comorbidities such as depression memory impairment. Unfortunately, still lacking establish full understanding underlying aspects This review has extensively discussed single nucleotide polymorphism (SNPs) genetic cause PTSD, implications inflammation, neurotransmitter genomics, metabolic alterations, neuroendocrine disturbance (hypothalamus-pituitary-adrenal (HPA) axis), dynamics, premature aging related PTSD-induced psychopathology neurophysiology. In addition, delineated importance CBT several pharmacodynamic mitigate symptomatology

Язык: Английский

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Post-traumatic stress disorder (PTSD) as a systemic disorder: Pathways to cardiovascular disease.

Health Psychology, Год журнала: 2021, Номер 41(10), С. 651 - 662

Опубликована: Ноя. 22, 2021

Evidence indicates that post-traumatic stress disorder (PTSD) is a significant risk factor for the development and progression of cardiovascular disease (CVD). Most explanations PTSD-CVD associations conceptualize PTSD as stress-related mental health elicits physiological, behavioral, psychological responses are causal factors in disorders. This article reviews evidence broader physical consequences PTSD, presents conceptual model based on research suggesting systemic disorder. Specifically, findings indicate diagnostic criteria just "tip iceberg" with elements factors. These physiological behavioral therefore should not be regarded accompanying but unrelated diseases or comorbidities, inherent components directly impact CVD. The approach has implications conceptualization factor, needed CVD, clinical efforts to reduce PTSD-associated risk. It suggested treatments aim need address both its associated Further test applicability perspective. (PsycInfo Database Record (c) 2022 APA, all rights reserved).

Язык: Английский

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The insomnia, fatigue, and psychological well‐being of hospital nurses 18 months after the COVID‐19 pandemic began: A cross‐sectional study

Journal of Clinical Nursing, Год журнала: 2022, Номер 33(1), С. 273 - 287

Опубликована: Июль 22, 2022

Abstract Background Research has shown sleep problems, elevated fatigue, and high cases of burnout, as well signs post‐traumatic stress psychological distress among nurses during the COVID‐19 pandemic. Many US hospitals attempted to minimise its impact on staff by providing basic resources, mental health services, wellness programs. Therefore, it is critical re‐evaluate these well‐being indices guide future administrative efforts. Purpose To determine long‐term pandemic after 18 months hospital nurses' insomnia, stress, distress. Design Cross‐sectional. Methods Data were collected online mainly through state board nursing association listservs between July–September 2021 ( N = 2488). The survey had psychometrically tested instruments (Insomnia Severity Index, Occupational Fatigue Exhaustion Recovery Scale, Maslach Burnout Inventory, Short Post‐Traumatic Stress Disorder, Patient Health Questionnaire‐4) sections demographics, health, work. STrengthening Reporting Observational studies in Epidemiology checklist was followed for reporting. Results Nurses subthreshold moderate‐to‐high chronic acute low‐to‐moderate intershift recovery. Regarding they experienced increased emotional exhaustion personal accomplishment, some depersonalisation. mild but scored stress. who frequently cared patients with past significantly worse all measures than their co‐workers. Factors such experience, shift length, frequency rest breaks related indices. Conclusion Nurses' experiences similar findings from early minor improvements provided patient care, worked ≥12 h per shift, skipped almost Relevance clinical practice Administration can help recovery support, treatment options re‐structure current work schedules ensure that are taken.

Язык: Английский

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Post-traumatic Stress Disorder: Focus on Neuroinflammation

Molecular Neurobiology, Год журнала: 2023, Номер 60(7), С. 3963 - 3978

Опубликована: Апрель 1, 2023

Язык: Английский

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Post Traumatic Stress Disorder associated Hypothalamic-Pituitary-Adrenal Axis Dysregulation and Physical Illness

Brain Behavior & Immunity - Health, Год журнала: 2024, Номер 41, С. 100849 - 100849

Опубликована: Авг. 23, 2024

Язык: Английский

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Prazosin for treatment of post-traumatic stress disorder: a systematic review and meta-analysis

CNS Spectrums, Год журнала: 2020, Номер 26(4), С. 338 - 344

Опубликована: Май 4, 2020

Prazosin has been an accepted treatment for patients with post-traumatic stress disorder (PTSD) who experience sleep disturbances, including nightmares. Results of a recent large randomized control trial did not find benefit prazosin vs placebo in improving such outcomes. A meta-analysis that includes this most was conducted to examine the pooled effect on disturbances and overall PTSD symptoms PTSD.A systematic review published literature trials comparing improvement scores, nightmares, quality conducted. Hedges' g standardized mean differences (SMD) between were calculated each outcome across studies.Six placebo-controlled studies representing 429 included analysis, two crossover design. showed significantly improved scores (SMD = -0.31; 95% confidence intervals [CI]: -0.62, -0.01), nightmares -0.75; CI: -1.24, -0.27), -0.57; -1.02, -0.13). In largest trial, reduction clinical measures similar past studies, but relatively size, particularly contributed no differences.Despite results recent, study, estimates show statistically significant disturbances. Limitations should be considered include heterogeneity study design populations as well small number meta-analysis.

Язык: Английский

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