Electrochemical Atom Transfer Radical Addition of Polychloroalkanes to Olefins Promoted by 4,4‐Di‐tert‐butyl Bipyridine
Chinese Journal of Chemistry,
Год журнала:
2023,
Номер
41(13), С. 1583 - 1588
Опубликована: Фев. 14, 2023
Comprehensive
Summary
A
new
electrochemical
strategy
for
the
atom
transfer
radical
addition
(ATRA)
of
polychloroalkanes
across
olefins
has
been
realized
by
synergism
paired
electrolysis
and
halogen
bonding
activation.
Notably,
readily
accessible
4,4‐di‐
tert
‐butyl
bipyridine
(dtbpy),
acting
as
a
acceptor,
shifted
reduction
potential
C—Cl
bonds
positively
110
mV.
The
decreased
operating
leads
to
wide
substrate
scope
excellent
functional
group
compatibility.
diverse
array
terminal
internal
alkenes
such
(hetero)aryl
olefins,
unactive
aliphatic
natural
products
drugs‐derived
were
well
compatible.
Язык: Английский
Recent Advances toward Electro- and Electrophotochemical 2,3-Dichloro-5,6-dicyano-1,4-benzoquinone (DDQ)-Catalyzed C—H/C—F Bonds Functionalization
Chinese Journal of Organic Chemistry,
Год журнала:
2025,
Номер
45(2), С. 668 - 668
Опубликована: Янв. 1, 2025
Язык: Английский
Role of delocalized electrons on the doping effect in vanadia
Chem,
Год журнала:
2023,
Номер
9(8), С. 2255 - 2266
Опубликована: Май 12, 2023
Язык: Английский
When transition-metal catalysis meets electrosynthesis: a recent update
Organic & Biomolecular Chemistry,
Год журнала:
2024,
Номер
22(22), С. 4390 - 4419
Опубликована: Янв. 1, 2024
The
merger
of
organic
electrosynthesis
with
3d
transition-metal
catalysis
has
offered
huge
opportunities
for
modern
synthesis.
This
review
summarizes
the
key
advancements
in
this
direction
published
recent
two
years.
Язык: Английский
Electrochemical Cobalt-Catalyzed C-H Hydroxyalkylation of N-Heteroarenes with Trifluoromethyl Ketones
Chinese Journal of Organic Chemistry,
Год журнала:
2023,
Номер
43(2), С. 789 - 789
Опубликована: Янв. 1, 2023
Язык: Английский
Convergent Paired Electrolysis for the Synthesis of Pyrazolyl‐Substituted Tetrahydroisoquinolines
Advanced Synthesis & Catalysis,
Год журнала:
2023,
Номер
365(23), С. 4198 - 4204
Опубликована: Окт. 24, 2023
Abstract
A
convergent
paired
electrolysis
method
for
the
synthesis
of
1‐pyrazolyl‐substituted
tetrahydroisoquinolines
has
been
developed.
The
reaction
proceeded
without
any
transition
metal
catalyst
and
chemical
oxidant.
desired
products
could
be
isolated
in
high
yields
(80–99%)
60–80
minutes.
Faradaic
efficiency
was
108%
gram‐scale
(84%)
carried
out.
Mechanistic
studies
revealed
that
C−N
bond
formation
process
might
mainly
involve
a
nucleophilic
addition
reaction.
Язык: Английский
Synthetic Access to 1,3-Butadiynes via Electro-redox Cuprous-Catalyzed Dehydrogenative Csp–Csp Homocoupling of Terminal Acetylenes
Synthesis,
Год журнала:
2023,
Номер
56(05), С. 777 - 786
Опубликована: Ноя. 8, 2023
Abstract
Herein,
we
disclose
the
oxidative
homocoupling
of
terminal
alkynes
under
electrochemically
generated
cuprous
catalysis.
The
scope
this
protocol
was
established
by
preparing
an
array
structurally
and
electronically
different
1,3-butadiyne
derivatives.
Good
synthetic
yields,
functional
group
tolerance,
oxidant-free
conditions,
no
cross-selectivity
are
some
intrinsic
advantages
methodology.
developed
chemistry
features
electro-redox
formation
copper
acetylide,
intermediate
appropriate
for
Csp–Csp
coupling
step.
chemical
state
in
acetylide
found
to
be
Cu(I),
as
confirmed
click
trapping
experiments,
cyclic
voltammetry,
EPR
spectroscopy,
XPS.
A
competition
reaction
determine
reactivity
dissimilar
acetylenes
revealed
that
product
ratio
is
rather
dependent
on
electronic
nature
alkynyl
substituents.
To
highlight
value
products,
selected
diynes
were
subjected
diversification.
Язык: Английский
I2-Mediated [3 + 3] Annulation for the Construction of Indole-Pyrimidine-Pyrazole-Fused Tetracyclic Heteroarenes
The Journal of Organic Chemistry,
Год журнала:
2024,
Номер
89(20), С. 15164 - 15169
Опубликована: Окт. 7, 2024
An
I2-mediated
annulation
of
3-aminopyrazoles
with
indole-3-carboxaldehydes
has
been
demonstrated
for
the
first
time.
This
tandem
strategy
allows
facile
construction
indole-pyrimidine-pyrazole-fused
tetracyclic
heteroarenes
that
are
otherwise
inaccessible
by
existing
methods.
These
fused
heterocycles
exhibited
enhanced
antifungal
activities
against
Valsa
mali
and
Botryosphaeria
dothidea
compared
commercial
Xemium
fungicide.
Язык: Английский