Electrochemical Difunctionalization of Alkenes
The Chemical Record,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 3, 2025
Abstract
Owing
to
their
wide
utilizations
in
synthesis
and
products
prevalence
numerous
natural
products,
pharmaceuticals
functional
materials,
the
alkene
difunctionalization
methods
for
selective
transformations
of
olefins
are
important
have
attracted
much
attention
form
synthetic
chemists.
Among
them,
electrochemical
reaction
is
particularly
promising
has
becoming
a
potent
sustainable
tool
alkenes
into
vicinal
difunctionalized
structures
organic
through
simultaneous
incorporation
two
groups.
Herein,
we
summarize
recent
progress
reactions
according
types
as
well
category
radicals
over
past
five
years.
By
selecting
remarkable
examples,
elaborately
discussed
substrate
scope
mechanisms
olefin
reaction.
Язык: Английский
Mn-Catalyzed Electrooxidative Radical Cascade Cyclization for the Synthesis of 6-Phosphorylated Quinoxalino[2,1-b]quinazolin-12-ones
The Journal of Organic Chemistry,
Год журнала:
2024,
Номер
unknown
Опубликована: Сен. 12, 2024
Due
to
their
important
potential
medicinal
value,
chemists
are
pursuing
mild
and
efficient
methods
synthesize
structurally
diverse
quinazolinone
derivatives.
In
this
paper,
a
series
of
isocyano-tethered
Язык: Английский
Electrooxidative Ni‐catalyzed Decarboxylation of Arylacetic Acids towards the Synthesis of carbonyls under Air Conditions
Chemistry - A European Journal,
Год журнала:
2024,
Номер
unknown
Опубликована: Сен. 16, 2024
Abstract
After
systematic
realization
of
decarboxylative
functionalization
carboxylic
acids
under
heating
conditions
in
our
group,
we
herein
reported
an
electrochemical
method
for
Ni‐catalyzed
oxygenation
arylacetic
open
air
conditions.
The
protocol
provided
corresponding
carbonyls
including
aldehydes
and
ketones
moderate
to
satisfactory
yields
with
good
functional
group
tolerance,
furthermore,
the
practicability
advantage
was
highlighted
through
oxidative
decarboxylation
acid‐containing
drugs
preformation
scalable
transformation.
Mechanistic
studies
demonstrated
that
possible
involvement
free
radical
intermediate
conversion.
Язык: Английский