Mycological Progress, Год журнала: 2025, Номер 24(1)
Опубликована: Янв. 15, 2025
Язык: Английский
Fungal Diversity, Год журнала: 2024, Номер 125(1), С. 1 - 71
Опубликована: Март 20, 2024
Abstract The field of mycology has grown from an underappreciated subset botany, to a valuable, modern scientific discipline. As this study grown, there have been significant contributions science, technology, and industry, highlighting the value fungi in era. This paper looks at current research, along with existing limitations, suggests future areas where scientists can focus their efforts, mycology. We show how become important emerging diseases medical discuss trends potential drug novel compound discovery. explore phylogenomics, its potential, outcomes address question phylogenomics be applied fungal ecology. In addition, functional genomics studies are discussed importance unravelling intricate mechanisms underlying behaviour, interactions, adaptations, paving way for comprehensive understanding biology. look research building materials, they used as carbon sinks, biocircular economies. numbers always great interest often written about estimates varied greatly. Thus, we needs order obtain more reliable estimates. aspects machine learning (AI) it mycological research. Plant pathogens affecting food production systems on global scale, such, needed area, particularly disease detection. latest data High Throughput Sequencing if still gaining new knowledge same rate before. A review nanotechnology is provided addressed. Arbuscular Mycorrhizal Fungi addressed acknowledged. Fungal databases becoming important, therefore provide major databases. Edible medicinal huge medicines, especially Asia prospects discussed. Lifestyle changes (e.g., endophytes, pathogens, and/or saprobes) also extremely trend special issue Diversity.
Язык: Английский
Процитировано
30
Fungal Diversity, Год журнала: 2024, Номер 126(1), С. 127 - 406
Опубликована: Июль 9, 2024
Язык: Английский
Процитировано
20
Coordination Chemistry Reviews, Год журнала: 2025, Номер 533, С. 216548 - 216548
Опубликована: Фев. 26, 2025
Язык: Английский
Процитировано
2
Fungal Biology, Год журнала: 2024, Номер 128(8), С. 2381 - 2389
Опубликована: Март 16, 2024
Язык: Английский
Процитировано
9
eFood, Год журнала: 2025, Номер 6(1)
Опубликована: Янв. 20, 2025
ABSTRACT Mushrooms have long been an integral part of human culture and health are valued for their nutritional therapeutic properties. Often referred to as a superfood, mushrooms rich in bioactive compounds that provide range benefits including antioxidant, antimicrobial, anticancer, prebiotic, antidiabetic, anti‐inflammatory effects. This review focussed on the diversity mushrooms, emphasizing medicinal significance, explores secondary metabolites with potential applications nutraceuticals pharmaceuticals. It underscores role vital agents developing value‐added products. An overview compounds, such polysaccharides, peptides, proteins, terpenoids, phenolic identified numerous mushroom species. Additionally, addresses advancements fungal biotechnology, particularly use fungi efficient industrial cell factories, influence food quality sustainability. By critically analyzing recent studies, summarizes diverse roles biomolecules pharmaceutical industries highlights significant contribution modern medicine health‐related fields.
Язык: Английский
Процитировано
1
New Phytologist, Год журнала: 2025, Номер unknown
Опубликована: Фев. 26, 2025
Summary Secondary metabolites are a crucial source of bioactive compounds playing key role in the development new pharmaceuticals. Recently, biosynthetic research has benefited significantly from progress on various fronts, including reduced sequencing costs, improved genome/metabolome mining strategies, and expanding tools/databases to compare characterize chemical diversity. Steady advances these fields for non‐modal organisms such as lichen‐forming fungi (LFF). Although most produce metabolites, LFF ( c . 21% known fungi) lags behind, primarily due experimental challenges. However, recent years, several challenges have been tackled, and, parallel, critical foundation genomic data pipelines established accomplish valorization this potential. Integrating concurrent accelerate biochemical provides promising opportunity discoveries. This review summarizes following: fungal omics, chemoinformatics research; studies biosynthesis, diversity evolutionary/phylogenetic aspects; milestones gene functions. At end, we outline vision strategy combine areas harness potential pharmaceutical development.
Язык: Английский
Процитировано
1
Angewandte Chemie International Edition, Год журнала: 2024, Номер 63(16)
Опубликована: Фев. 23, 2024
Abstract In this investigation, we explored the diversity of melleolide‐type meroterpenoids produced by Armillaria ostoyae , one largest and oldest organisms on Earth, using extracts from liquid solid fermentation media. The study unveiled three unprecedented dimeric bismelleolides novel fatty‐acid‐substituted congeners, along with 11 new 21 known derivatives. structures were elucidated 1D 2D NMR spectroscopy HRESI‐MS, ROESY spectral analysis for relative configurations. Absolute configurations determined crystal through ECD spectra comparison. A compound library facilitated metabolomics‐wide associations, revealing production patterns under different culture conditions. enabled assessments antimicrobial cytotoxic activities, that Δ 2,4 double bond is not crucial antifungal activity. Cytotoxicity was linked to presence an aldehyde at C1, but lost hydroxylation C13. Chemoinformatic analyses demonstrated intricate interplay chemical modifications biological properties. This marks first systematic exploration spp. meroterpenoid MS‐based untargeted metabolomics, offering insight into structure–activity relationships innovative chemoinformatics.
Язык: Английский
Процитировано
8
Fungal Diversity, Год журнала: 2024, Номер 128(1), С. 1 - 165
Опубликована: Окт. 15, 2024
Abstract Fungi are one of the most diverse groups organisms with an estimated number species in range 2–3 million. The higher-level ranking fungi has been discussed framework molecular phylogenetics since Hibbett et al., and definition higher ranks (e.g., phyla) ‘true fungi’ have revised several subsequent publications. Rapid accumulation novel genomic data advancements now facilitate a robust precise foundation for classification within kingdom. This study provides updated kingdom , drawing upon comprehensive phylogenomic analysis Holomycota which we outline well-supported nodes fungal tree explore more contentious groupings. We accept 19 phyla Fungi, viz . Aphelidiomycota Ascomycota Basidiobolomycota Basidiomycota Blastocladiomycota Calcarisporiellomycota Chytridiomycota Entomophthoromycota Entorrhizomycota Glomeromycota Kickxellomycota Monoblepharomycota Mortierellomycota Mucoromycota Neocallimastigomycota Olpidiomycota Rozellomycota Sanchytriomycota, Zoopagomycota In phylogenies, Caulochytriomycota resides ; thus, former is regarded as synonym latter, while Caulochytriomycetes viewed class provide description each phylum followed by its classes. A new subphylum, Sanchytriomycotina Karpov introduced only subphylum Sanchytriomycota subclass Pneumocystomycetidae Kirk al. Pneumocystomycetes invalid thus validated. Placements fossil classes also discussed, providing examples.
Язык: Английский
Процитировано
8
Separations, Год журнала: 2024, Номер 11(6), С. 186 - 186
Опубликована: Июнь 13, 2024
Fungal proteins are highlighted for their nutritional value and bioactive properties, making them a significant alternative to traditional protein sources. This review evaluates various green extraction technologies, including enzymatic-, ultrasound-, higher-pressure homogenization-, microwave-assisted, pulsed electric fields-, supercritical fluid-assisted extraction, focusing on effectiveness in disrupting fungal cell walls preserving integrity. The findings indicate that these technologies could have the potential improve yield quality, addressing challenges posed by walls’ complex resilient structure. also underscores bioactivities of proteins, antifungal, antibacterial, antioxidant, anticancer properties. conclusion emphasises need further optimisation scaling as well exploring wider range species fully understand sustainable Future research directions include refining methods, integrating multiple approaches, utilising novel solvents maximise efficiency yield.
Язык: Английский
Процитировано
7
BioNanoScience, Год журнала: 2024, Номер 14(4), С. 4145 - 4166
Опубликована: Авг. 6, 2024
Язык: Английский
Процитировано
7