QbD Manoeuvred Niclosamide Laden Polylactic-co-Glycolic Acid Nanoparticles-Impregnated Gelatin Nanofibers for the Management of Oral Carcinoma
BioNanoScience,
Год журнала:
2025,
Номер
15(2)
Опубликована: Фев. 5, 2025
Язык: Английский
Navigating the Brain: Harnessing Endogenous Cellular Hitchhiking for Targeting Neoplastic and Neuroinflammatory Diseases
Asian Journal of Pharmaceutical Sciences,
Год журнала:
2025,
Номер
unknown, С. 101040 - 101040
Опубликована: Фев. 1, 2025
Язык: Английский
Nanoparticle-enhanced delivery of resveratrol for targeted therapy of glioblastoma: Modulating the Akt/GSK-3β/NF-kB pathway in C6 glioma cells
Brain Research,
Год журнала:
2024,
Номер
unknown, С. 149411 - 149411
Опубликована: Дек. 1, 2024
Язык: Английский
Progress in Drug Delivery Systems Based on Nanoparticles for Improved Glioblastoma Therapy: Addressing Challenges and Investigating Opportunities
Cancers,
Год журнала:
2025,
Номер
17(4), С. 701 - 701
Опубликована: Фев. 19, 2025
Glioblastoma
multiforme
(GBM)
is
a
highly
malignant
brain
tumor
that
has
bleak
outlook
despite
existing
treatments
such
as
surgery,
radiation,
and
chemotherapy.
The
utilization
of
nanoparticles
for
drug
delivery
presents
promising
method
by
which
to
improve
the
effectiveness
treatment
while
reducing
harmful
effects
on
entire
body.
This
review
examines
application
in
GBM,
focusing
different
types
nanoparticles,
including
lipid-based,
polymeric,
metallic,
those
under
development.
Every
variety
analyzed
its
distinct
characteristics
therapeutic
capacity.
Lipid-based
liposomes
solid
lipid
enhance
transport
medicines
are
not
soluble
water
have
shown
considerable
potential
preclinical
investigations.
Polymeric
benefits
terms
controlled
release
targeted
distribution,
whereas
metallic
both
therapy
imaging.
In
current
we
would
like
emphasize
ways
medicine
delivery,
specifically
enhancing
penetration
blood-brain
barrier
(BBB),
targeting
tumors,
enabling
release.
Additionally,
also
discuss
clinical
discoveries,
highlighting
achievements
obstacles
process
converting
these
technologies
into
effective
GBM.
study
offers
thorough
examination
present
status
prospects
Язык: Английский
Metal-Organic Frameworks as Therapeutic Chameleons: Revolutionizing the Cancer Therapy Employing Novel Nanoarchitectonics
Sajja Bhanu Prasad,
Akshay Shinde,
Dadi A. Srinivasrao
и другие.
Asian Journal of Pharmaceutical Sciences,
Год журнала:
2025,
Номер
unknown, С. 101054 - 101054
Опубликована: Апрель 1, 2025
Язык: Английский
Next-Generation Transformable Nanomedicines: Revolutionizing Cancer Drug Delivery and Theranostics
Swapnil Shinde,
Saurabh Shah,
Paras Famta
и другие.
Molecular Pharmaceutics,
Год журнала:
2025,
Номер
unknown
Опубликована: Май 3, 2025
Nanomedicine
has
significantly
advanced
the
treatment
of
various
cancer
phenotypes,
addressing
numerous
challenges
associated
with
conventional
therapies.
Researchers
have
extensively
investigated
physicochemical
properties
nanocarriers,
such
as
charge,
morphology,
and
surface
chemistry,
to
optimize
drug
delivery
systems.
In
context
transformable
nanomedicine,
these
are
particularly
critical
for
overcoming
existing
limitations,
including
suboptimal
blood
circulation
times,
sequestration
by
reticuloendothelial
system
mononuclear
phagocyte
system,
inefficient
targeting
tumor
microenvironment
(TME).
Alterations
in
nanocarrier
geometry,
hydrophilicity
shown
potential
mitigating
barriers,
offering
improved
therapeutic
outcomes
enhanced
biomedical
applications.
This
review
explores
controlled
modulation
anticancer
therapy,
an
in-depth
exploration
strategies
activated
both
internal
external
stimuli.
We
analyze
implications
tunable
characteristics
on
pharmacokinetics,
biodistribution,
targeted
TME.
Additionally,
we
address
current
clinical
translation
nanocarriers
propose
overcome
obstacles
enhance
feasibility
nanomedicine-based
Язык: Английский