Frontiers in Plant Science,
Год журнала:
2022,
Номер
13
Опубликована: Дек. 12, 2022
The
global
environment
is
dominated
by
various
small
exotic
substances,
known
as
secondary
metabolites,
produced
plants
and
microorganisms.
Plants
fungi
are
particularly
plentiful
sources
of
these
molecules,
whose
physiological
functions,
in
many
cases,
remain
a
mystery.
Fungal
metabolites
(SM)
diverse
group
substances
that
exhibit
wide
range
chemical
properties
generally
fall
into
one
four
main
family
groups:
Terpenoids,
polyketides,
non-ribosomal
peptides,
or
combination
the
latter
two.
They
incredibly
varied
their
functions
often
related
to
increased
fitness
respective
fungus
its
environment,
competing
with
other
microbes
interacting
plant
species.
Several
have
essential
roles
biological
control
diseases
beneficial
microorganisms
used
for
crop
protection
biofertilization
worldwide.
Besides
direct
toxic
effects
against
phytopathogens,
natural
can
promote
root
shoot
development
and/or
disease
resistance
activating
host
systemic
defenses.
ability
synthesize
store
biologically
active
potent
source
novel
compounds
agriculture
becoming
top
priority
SM
research.
In
this
review,
we
will
discuss
fungal-plant
antifungal
role
signaling
molecules
induced
acquired
activities.
Additionally,
fungal
mimic
promotion
such
auxins,
gibberellins,
abscisic
acid,
which
modulate
growth
under
biotic
stress.
Moreover,
present
new
trend
regarding
phytoremediation
applications
using
achieve
sustainable
food
production
microbial
diversity
an
eco-friendly
environment.
Journal of Fungi,
Год журнала:
2025,
Номер
11(2), С. 93 - 93
Опубликована: Янв. 24, 2025
Metabolomics
has
emerged
as
a
transformative
tool
in
the
study
of
microbes,
including
pathogenic
fungi,
facilitating
identification
unique
metabolic
profiles
that
elucidate
their
mechanisms,
host
interactions,
and
treatment
resistance.
This
review
highlights
key
applications
metabolomics
understanding
fungal
metabolites
essential
for
human
virulence,
such
mycotoxins
produced
by
various
species,
Aspergillus
fumigatus
(gliotoxin,
fumagillins)
Candida
species
(phenylethyl
alcohol,
TCA
cycle
metabolites),
secondary
contribute
to
pathogenicity.
It
also
explores
adaptations
fungi
relation
drug
resistance
biofilm
formation,
revealing
alterations
pathways
during
infection,
seen
C.
albicans
auris.
Furthermore,
aids
deciphering
host–pathogen
showcasing
how
like
Cryptococcus
neoformans
modify
metabolism
promote
survival
evade
immune
responses.
The
antifungal
mechanisms
benefited
from
metabolomic
approaches,
identifying
specific
metabolite
patterns
signify
resistance,
Candidozyma
(Candida)
auris,
informing
new
therapeutic
strategies.
integration
with
other
omics
technologies
is
paving
way
comprehensive
biology
pathogenesis.
Such
multi-omics
approaches
are
crucial
discovering
targets
developing
innovative
treatments.
Thus,
purpose
this
provide
an
overview
revolutionizing
our
pathogenesis,
highlight
its
potential
improving
Expert Review of Anti-infective Therapy,
Год журнала:
2022,
Номер
20(6), С. 897 - 906
Опубликована: Фев. 19, 2022
Mitigation
of
infectious
diseases
resulted
from
antibiotic-resistant
bacteria
is
difficult
by
current
antibiotics.
Metal
and
metal
oxide
nanoparticles
specifically
Ag
can
be
efficient
antibacterial
agents
considering
their
biocompatibility.
In
this
way,
biosynthesis
living
organisms
or
metabolites
has
obtained
more
attention
compared
to
chemical
physical
methods.Bacteria
fungi
in
extracellular
intracellular
pathways
related
primary
secondary
synthesize
with
synergistic
activity
against
bacterial
pathogens.Bacteriostatic
bactericidal
effects
these
lead
production
reactive
oxygen
species
inactivation
biological
macromolecules
such
as
proteins
nucleic
acids.
The
present
review
tried
discuss
recent
progress
challenges
about
mechanisms
bio-inspired
archaebacteria,
actinomycetes,
cyanobacteria,
fungi.
International Journal of Food Properties,
Год журнала:
2023,
Номер
26(1), С. 1822 - 1840
Опубликована: Июль 19, 2023
Food
security
has
become
a
major
issue
around
the
globe.
Even
today
food
is
not
accessible
to
every
person
of
this
world.
United
Nations
set
target
for
everyone
by
2030,
but
still,
we
are
very
far
away
from
target.
Millets
four
season
crop,
which
cultivated
globally
post-green
revolution
era,
their
cultivation
significantly
declined
due
more
accentuation
on
rice,
wheat
and
maize.
The
primary
suppliers
carbohydrates
humanity
dependent
lack
essential
amino
acids
minerals
cardinal
proper
nutrition.
This
nutrients
in
diet
lifestyles
welcomes
numerous
diseases
like
cardiovascular
diseases,
obesity
diabetes.
unique
richness
dietary
fibers,
antioxidants,
protein,
fats.
present
global
spectacle
climate
alternate
forced
us
sustain
our
natural
resources.
In
case,
millets
ones
that
poor
soils.
review
article
reviews
beneficiaries
millet
contrast
human
health
as
certain
polyphenols
catechin,
sinapic
acid,
found
have
many
sustaining
benefits
prevention
against
arthritis,
cancer,
inflammation,
environment
compared
staple
grains
minimum
water
requirement,
less
fertile
soils,
usage
pesticides
fertilizers
provides
nurturing
ecosystem.
incorporation
into
daily
an
individual
might
help
curing
complications.
Frontiers in Plant Science,
Год журнала:
2023,
Номер
14
Опубликована: Июль 10, 2023
The
most
significant
issues
that
humans
face
today
include
a
growing
population,
an
altering
climate,
reliance
on
pesticides,
the
appearance
of
novel
infectious
agents,
and
accumulation
industrial
waste.
production
agricultural
goods
has
also
been
subject
to
great
number
shifts,
often
known
as
revolutions,
which
have
influenced
by
progression
civilization,
technology,
general
human
advancement.
Sustainable
measures
can
be
applied
in
agriculture,
environment,
medicine,
industry
are
needed
lessen
harmful
effects
aforementioned
problems.
Endophytes,
might
bacterial
or
fungal,
could
successful
solution.
They
protect
plants
promote
growth
producing
phytohormones
providing
biotic
abiotic
stress
tolerance.
Endophytes
produce
diverse
type
bioactive
compounds
such
alkaloids,
saponins,
flavonoids,
tannins,
terpenoids,
quinones,
chinones,
phenolic
acids
etc.
for
various
therapeutic
advantages
anticancer,
antitumor,
antidiabetic,
antifungal,
antiviral,
antimicrobial,
antimalarial,
antioxidant
activity.
Proteases,
pectinases,
amylases,
cellulases,
xylanases,
laccases,
lipases,
other
types
enzymes
vital
many
different
industries
produced
endophytes.
Due
presence
all
these
endophytes,
they
preferred
sources
green
synthesis
nanoparticles.
This
review
aims
comprehend
contributions
uses
endophytes
medicinal,
sectors
bio-nanotechnology
with
their
mechanism
action.
