Zastita materijala,
Год журнала:
2024,
Номер
unknown
Опубликована: Окт. 11, 2024
Contamination
by
pathogenic
bacteria
represents
a
severe
risk
to
public
health
and
well-being.
We
outlined
current
approaches
detecting
sensing
harmful
integrating
recognition
elements
with
nanomaterials
(NMs)
in
this
study.
Nanomaterials
have
emerged
as
transformative
technology
for
bacterial
detection
due
their
unique
physicochemical
properties,
including
high
surface
area,
quantum
effects,
enhanced
reactivity.
This
review
highlights
the
trends
application
of
various
nanomaterials,
such
gold
nanoparticles,
carbon
nanotubes,
dots,
pathogens.
These
materials
enable
development
selective,
rapid
methods
through
mechanisms
like
plasmon
resonance,
electrochemical
sensing,
fluorescence.
Furthermore,
microfluidic
devices
biosensors
is
discussed,
showcasing
advancements
point-of-care
diagnostics.
Challenges
stability,
reproducibility,
potential
toxicity
are
addressed,
alongside
regulatory
considerations.
The
future
outlook
emphasizes
emerging
graphene
metal-organic
frameworks,
revolutionize
detection.
aims
enhance
scalability,
cost-effectiveness,
environmental
sustainability
these
technologies,
paving
way
widespread
clinical
applications.
Microbial Cell Factories,
Год журнала:
2025,
Номер
24(1)
Опубликована: Янв. 21, 2025
Outer
membrane
vesicles
(OMVs),
shed
by
Gram-negative
bacteria,
are
spherical
nanostructures
that
play
a
pivotal
role
in
bacterial
communication
and
host-pathogen
interactions.
Comprising
an
outer
envelope
encapsulating
variety
of
bioactive
molecules
from
their
progenitor
OMVs
facilitate
material
informational
exchange.
This
review
delves
into
the
recent
advancements
OMV
research,
providing
comprehensive
overview
structure,
biogenesis,
mechanisms
vesicle
formation.
It
also
explores
pathogenicity
techniques
for
enrichment
isolation.
Furthermore,
highlights
burgeoning
applications
field
biomedicine,
emphasizing
potential
as
diagnostic
tools,
vaccine
candidates,
drug
delivery
vectors.
Malignant
bone
tumors,
which
are
difficult
to
treat
with
current
clinical
strategies,
originate
from
tissues
and
can
be
classified
into
primary
secondary
types.
Due
the
specificity
of
microenvironment,
results
traditional
means
treating
tumors
often
unsatisfactory,
so
there
is
an
urgent
need
develop
new
treatments
for
malignant
tumors.
Recently,
nanoparticle-based
approaches
have
shown
great
potential
in
diagnosis
treatment.
Nanoparticles
(NPs)
gained
significant
attention
due
their
versatility,
making
them
highly
suitable
applications
tissue
engineering,
advanced
imaging
techniques,
targeted
drug
delivery.
For
diagnosis,
NPs
enhance
contrast
sensitivity
by
integrating
targeting
ligands,
significantly
improve
specific
recognition
localization
tumor
cells
early
detection.
treatment,
enable
delivery,
increasing
accumulation
at
sites
while
reducing
systemic
toxicity.
In
conclusion,
understanding
microenvironment
using
unique
properties
holds
promise
improving
disease
management,
enhancing
treatment
outcomes,
ultimately
quality
life
patients
Further
research
development
will
undoubtedly
contribute
advancement
personalized
medicine
field
oncology.
Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology,
Год журнала:
2024,
Номер
15(1)
Опубликована: Ноя. 7, 2024
Abstract
Probiotic
extracellular
vesicles
(pEVs)
are
biologically
active
nanoparticle
structures
that
can
regulate
the
intestinal
tract
through
direct
or
indirect
mechanisms.
They
enhance
barrier
function
in
livestock
and
poultry
help
alleviate
diseases.
The
specific
effects
of
pEVs
depend
on
their
internal
functional
components,
including
nucleic
acids,
proteins,
lipids,
other
substances.
This
paper
presents
a
narrative
review
impact
across
various
segments
tract,
exploring
mechanisms
action
while
highlighting
limitations
current
research.
Investigating
which
probiotics
operate
via
could
deepen
our
understanding
provide
theoretical
foundation
for
application
production.
Frontiers in Immunology,
Год журнала:
2025,
Номер
16
Опубликована: Фев. 4, 2025
Sepsis
is
a
systemic
injury
resulting
in
vascular
dysfunction,
which
can
lead
to
multiple
organ
even
shock
and
death.
Extracellular
vesicles
(EVs)
released
by
mammalian
cells
bacteria
have
been
shown
play
important
roles
intercellular
communication
progression
of
various
diseases.
In
past
decades,
the
functional
role
EVs
sepsis
its
complications
has
well
explored.
are
one
paracrine
components
cells.
By
delivering
bioactive
materials,
promote
immune
responses,
particularly
development
inflammation.
addition,
serve
as
beneficial
tools
for
therapeutic
cargos.
this
review,
we
discuss
dual
treatment
sepsis,
exploring
their
intricate
involvement
both
inflammation
tissue
repair
processes.
Specifically,
remarkable
engineered
strategies
based
on
highlighted.
The
engineering
EVs-mediated
drug
delivery
release
offer
broad
prospects
effective
sepsis.
EVs-based
approaches
provide
novel
avenue
diagnosing
opportunities
more
precise
intervention.
Chemical Communications,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 1, 2025
Extracellular
vesicles
have
been
deemed
as
potential
drug
carriers
for
treatment
of
various
diseases.
Recent
advances
summarized,
including
the
sources,
delivery
function,
extraction
and
cargo-loading
technology
extracellular
vesicles.
Materials Today Bio,
Год журнала:
2025,
Номер
32, С. 101646 - 101646
Опубликована: Март 11, 2025
With
the
ever-increasing
burden
of
urological
diseases,
need
for
developing
novel
imaging
biomarkers
and
therapeutics
to
manage
these
disorders
has
never
been
greater.
Extracellular
vesicles
(EVs)
are
natural
membranous
nanoparticles
widely
applied
in
both
diagnostics
many
diseases.
A
growing
body
research
demonstrated
that
EVs
can
be
engineered
enhance
their
efficiency,
specificity,
safety.
We
systematically
examine
strategies
achieving
targeted
delivery
as
well
techniques
engineering
them
this
review,
with
a
particular
emphasis
on
cargo
loading
transportation.
Additionally,
review
highlights
summarizes
wide
range
therapeutic
applications
context
emphasizing
potential
malignancy
kidney
