Recent advancements in photothermal anti-icing/deicing materials

Chemical Engineering Journal, Год журнала: 2023, Номер 469, С. 143924 - 143924

Опубликована: Июнь 3, 2023

Язык: Английский

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Design of One-for-All Near-Infrared Aggregation-Induced Emission Nanoaggregates for Boosting Theranostic Efficacy

ACS Nano, Год журнала: 2023, Номер 17(5), С. 4591 - 4600

Опубликована: Март 1, 2023

Fluorescence-guided phototherapy, including photodynamic and photothermal therapy, is considered an emerging noninvasive strategy for cancer treatments. Organic molecules are promising theranostic agents because of their facile construction, simple modification, good biocompatibility. systems that integrated multifunctionalities in a single component achieved high efficiency both imaging therapies rarely reported as the inherently competitive energy relaxation pathways hard to modulate, fluorescence quenching occurs upon molecular aggregation. Herein, versatile platform with near-infrared emission, quantum yield, robust reactive oxygen species production, excellent conversion was developed based on aggregation-induced emission luminogen, namely, TPA-TBT. In vivo studies revealed TPA-TBT nanoaggregates exhibit outstanding therapy efficacy ablate tumors inoculated mouse model. This work offers design develop one-for-all by modulating utilizing excitons full.

Язык: Английский

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Recent advances in fluorescence imaging-guided photothermal therapy and photodynamic therapy for cancer: From near-infrared-I to near-infrared-II

Journal of Controlled Release, Год журнала: 2023, Номер 362, С. 425 - 445

Опубликована: Сен. 8, 2023

Язык: Английский

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Development of Polymethine Dyes for NIR‐II Fluorescence Imaging and Therapy

Advanced Healthcare Materials, Год журнала: 2024, Номер 13(16)

Опубликована: Март 5, 2024

Fluorescence imaging in the second near-infrared window (NIR-II) is burgeoning because of its higher fidelity monitoring physiological and pathological processes than clinical visible/the fluorescence imaging. Notably, heavily dependent on agents. So far, indocyanine green, one polymethine dyes, with good biocompatibility renal clearance only dye approved by Food Drug Administration, but it shows relatively low NIR-II brightness. Importantly, tremendous efforts are devoted to synthesizing dyes for preclinically clinically. They have shown feasibility customization structure properties fulfill various needs therapy. Herein, a timely update special focus molecular design strategies fluorescent, photoacoustic, multimodal imaging, offered. Furthermore, progress sensing biomarkers even reporting drug release illustrated. Moreover, imaging-guided therapies summarized regarding chemo-, photothermal, photodynamic, approaches. In addition, artificial intelligence pointed out potential expedite development. This comprehensive review will inspire interest among wide audience offer handbook people an dyes.

Язык: Английский

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NIR‐II Excitable Semiconducting Polymers with AIE Characteristics for Fluorescence‐Photoacoustic Imaging‐Guided Synergistic Phototherapy

Advanced Functional Materials, Год журнала: 2024, Номер 34(32)

Опубликована: Март 22, 2024

Abstract The development of semiconducting polymers (SPs) with simultaneous second near‐infrared (NIR‐II) absorption and multimodal phototheranostic functions is highly desired in the field oncotherapy. Aggregation‐induced emission luminogens (AIEgens) have been acknowledged to possess unique potential integrating multiple diagnostic therapeutic modalities into one organic molecule. Nevertheless, SPs are hard achieve AIE activity due their extended π‐conjugated skeletons as well large planar configuration commonly‐used electrophilic acceptor moieties. Herein, an ingenious dimerization‐based distortion strategy proposed current work by taking advantage sterically encumbered acceptors structure for successful construction AIE‐active SPs. Through further finely adjusting molecular donor–acceptor interaction strength, obtained named SP3 bearing highest intramolecular charge transfer effect presented NIR‐II aggregation‐induced fluorescence emission, good reactive oxygen species production ability, superior photothermal conversion performance. Accordingly, selected fabricate nanoparticles successfully applied laser‐triggered fluorescence‐photoacoustic imaging‐guided photodynamic‐photothermal therapy tumors. This study represents first excitable SP, offers a new perspective on designing advanced efficient treatment malignant tumor.

Язык: Английский

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Harnessing Hafnium‐Based Nanomaterials for Cancer Diagnosis and Therapy

Small, Год журнала: 2023, Номер 19(32)

Опубликована: Апрель 8, 2023

Abstract With the rapid development of nanotechnology and nanomedicine, there are great interests in employing nanomaterials to improve efficiency disease diagnosis treatment. The clinical translation hafnium oxide (HfO 2 ), commercially namedas NBTXR3, as a new kind nanoradiosensitizer for radiotherapy (RT) cancers has aroused extensive interest researches on Hf‐based biomedical application. In past 20 years, have emerged potential important nanomedicine computed tomography (CT)‐involved bioimaging RT‐associated cancer treatment due their excellent electronic structures intrinsic physiochemical properties. this review, bibliometric analysis method is employed summarize progress synthesis technology various nanomaterials, including HfO , ‐based compounds, Hf‐organic ligand coordination hybrids, such metal‐organic frameworks or nanoscaled polymers. Moreover, current states application CT‐involved contrasts tissue imaging reviewed detail. Importantly, recent advances nanomaterials‐mediated radiosensitization synergistic RT with other mainstream treatments also generalized. Finally, challenges future perspectives view maximize research translational medicine discussed.

Язык: Английский

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Rational design of biodegradable semiconducting polymer nanoparticles for NIR-II fluorescence imaging-guided photodynamic therapy

Nano Research, Год журнала: 2024, Номер 17(6), С. 5399 - 5408

Опубликована: Янв. 19, 2024

Язык: Английский

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A perylene diimide probe for NIR-II fluorescence imaging guided photothermal and type I/type II photodynamic synergistic therapy

Biosensors and Bioelectronics, Год журнала: 2024, Номер 259, С. 116424 - 116424

Опубликована: Май 23, 2024

Язык: Английский

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Acceptor-engineering tailored type-I photosensitizer with aggregation-induced NIR-II emission for cancer multimodal phototheranostics

Science China Chemistry, Год журнала: 2024, Номер 67(8), С. 2647 - 2660

Опубликована: Июнь 26, 2024

Язык: Английский

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Biodegradable Cascade‐Amplified Nanotheranostics for Photoacoustic‐Guided Synergistic PTT/CDT/Starvation Antitumor in the NIR‐II Window

Advanced Healthcare Materials, Год журнала: 2024, Номер unknown

Опубликована: Июнь 22, 2024

The development of nanoassemblies, activated by the tumor microenvironment, capable generating photothermal therapy (PTT) and amplifying "ROS (·OH) storm," is essential for precise effective synergistic treatment. Herein, an innovative cascade-amplified nanotheranostics based on biodegradable Pd-BSA-GOx nanocomposite NIR-II photoacoustic imaging (PAI) guides self-enhanced PTT/chemodynamic (CDT)/starvation therapy. demonstrates ability to selectively convert overexpressed H

Язык: Английский

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