Extracellular vesicles as biomarkers and drug delivery systems for tumor DOI Creative Commons
Xue Wang, Wenjing Chen, Wei Zeng

и другие.

Acta Pharmaceutica Sinica B, Год журнала: 2025, Номер unknown

Опубликована: Май 1, 2025

Язык: Английский

Plant-derived nanovesicles and therapeutic application DOI Creative Commons
Dokyung Jung,

Na-Eun Kim,

Je Hyeong Kim

и другие.

Pharmacology & Therapeutics, Год журнала: 2025, Номер unknown, С. 108832 - 108832

Опубликована: Фев. 1, 2025

Язык: Английский

Процитировано

1
Fucoidan-modified antibiotic-free nanovesicles: A multidimensional approach to eradicate intracellular and extracellular Helicobacter pylori and restore gastrointestinal homeostasis DOI
Shuqi Zhang,

Shi-Jie Ma,

Suqi Hao

и другие.

International Journal of Biological Macromolecules, Год журнала: 2025, Номер 307, С. 141786 - 141786

Опубликована: Март 7, 2025

Язык: Английский

Процитировано

1
Plant-Derived Extracellular Vesicles as a Promising Anti-Tumor Approach: A Comprehensive Assessment of Effectiveness, Safety, and Mechanisms DOI
Qiang Wei, Jing Li,

Rui Ruan

и другие.

Phytomedicine, Год журнала: 2024, Номер 130, С. 155750 - 155750

Опубликована: Май 19, 2024

Язык: Английский

Процитировано

5
Solanum lycopersicum derived exosome-like nanovesicles alleviate restenosis after vascular injury through the Keap1/Nrf2 pathway DOI Creative Commons
Hechen Shen, Meng Zhang, Dachang Liu

и другие.

Food & Function, Год журнала: 2024, Номер unknown

Опубликована: Дек. 16, 2024

Exosome-like nanovesicles derived from Solanum lycopersicum show potential to inhibit vascular restenosis. The underlying mechanism involves activation of the Keap1/Nrf2 signaling pathway by miRNA164a/b-5p.

Язык: Английский

Процитировано

4
Plant-Derived Vesicle-like Nanoparticles: The Next-Generation Drug Delivery Nanoplatforms DOI Creative Commons
Xiaoxia Wang,

Congling Xin,

Yu Zhou

и другие.

Pharmaceutics, Год журнала: 2024, Номер 16(5), С. 588 - 588

Опубликована: Апрель 26, 2024

A wide variety of natural bioactive compounds derived from plants have demonstrated significant clinical relevance in the treatment various diseases such as cancer, chronic disease, and inflammation. An increasing number studies surfaced that give credence to potential plant-derived vesicle-like nanoparticles (PDVLNs) compelling candidates for a drug delivery system (DDS). PDVLNs are cost-effective production, non-toxicity non-immunogenicity fascinating bi-ocompatibility. In this review, we attempt comprehensively review consolidate position next-generation nanoplatforms. We aim quick glance readers current developments PDVLNs, including their biogenesis, characteristic features, composition, administration routes, advantages, application. Further, discuss advantages limitations PDVLNs. expect role will be significantly enhanced, thus positioning them next generation therapeutic modalities foreseeable future.

Язык: Английский

Процитировано

3
Applications of plant‐derived extracellular vesicles in medicine DOI Creative Commons

Yawen Zhu,

Junqi Zhao, Haoran Ding

и другие.

MedComm, Год журнала: 2024, Номер 5(10)

Опубликована: Сен. 20, 2024

Plant-derived extracellular vesicles (EVs) are promising therapeutic agents owing to their natural abundance, accessibility, and unique biological properties. This review provides a comprehensive exploration of the potential plant-derived EVs emphasizes anti-inflammatory, antimicrobial, tumor-inhibitory effects. Here, we discussed advancements in isolation purification techniques, such as ultracentrifugation size-exclusion chromatography, which critical for maintaining functional integrity these nanovesicles. Next, investigated diverse administration routes carefully weighed respective advantages challenges related bioavailability patient compliance. Moreover, elucidated multifaceted mechanisms action EVs, including roles anti-inflammation, antioxidation, antitumor activity, modulation gut microbiota. We also impact on specific diseases cancer inflammatory bowel disease, highlighting importance addressing current production scalability, regulatory compliance, immunogenicity. Finally, proposed future research directions optimizing EV extraction developing targeted delivery systems. Through efforts, envision seamless integration into mainstream medicine, offering safe potent alternatives across various medical disciplines.

Язык: Английский

Процитировано

3
Blueberry-derived exosome like nanovesicles carry RNA cargo into HIEC-6 cells and down-regulate LPS-induced inflammatory gene expression: a proof-of-concept study DOI
Sharon Natasha Cox,

Vito Porcelli,

Simona Romano

и другие.

Archives of Biochemistry and Biophysics, Год журнала: 2024, Номер unknown, С. 110266 - 110266

Опубликована: Дек. 1, 2024

Язык: Английский

Процитировано

3
Essential oils of Tagetes patula: a study on ultrasound-assisted extraction, characterization, and in vitro biological profiles DOI
D.K. Mohanty,

Ganeswar Dalei,

Subhraseema Das

и другие.

Biomass Conversion and Biorefinery, Год журнала: 2025, Номер unknown

Опубликована: Янв. 23, 2025

Язык: Английский

Процитировано

0
Utility of edible plant-derived exosome-like nanovesicles as a novel delivery platform for vaccine antigen delivery DOI

Hyun‐Jin Kim,

Sanghoon Lee,

Yu-Seong Park

и другие.

Vaccine, Год журнала: 2025, Номер 52, С. 126902 - 126902

Опубликована: Фев. 26, 2025

Язык: Английский

Процитировано

0
Exosomes: A Promising Drug Delivery Tool in Hepatic Drug Delivery DOI
Neha Kanojia,

Komal Thapa,

Thakur Gurjeet Singh

и другие.

Journal of Drug Delivery Science and Technology, Год журнала: 2025, Номер unknown, С. 106761 - 106761

Опубликована: Март 1, 2025

Язык: Английский

Процитировано

0