PLoS ONE,
Год журнала:
2023,
Номер
18(4), С. e0284075 - e0284075
Опубликована: Апрель 7, 2023
Prolonged
symptoms
of
COVID-19
have
been
found
in
many
patients,
often
known
as
Long
COVID.
Psychiatric
are
commonly
seen
COVID
patients
and
could
last
for
weeks,
even
months,
after
recovery.
However,
the
risk
factors
associated
with
it
remain
unclear.
In
current
systematic
review,
we
provide
an
overview
psychiatric
development
those
symptoms.
Articles
were
systematically
searched
on
SCOPUS,
PubMed,
EMBASE
up
to
October
2021.
Studies
involving
adults
geriatric
participants
a
confirmed
previous
diagnosis
reported
that
persist
more
than
four
weeks
initial
infection
included.
The
bias
was
assessed
using
Newcastle-Ottawa
Scale
(NOS)
observational
studies.
Prevalence
rates
collected.
This
present
study
registered
at
PROSPERO
(CRD42021240776).
total,
23
studies
Several
limitations
this
review
heterogeneity
studies’
outcomes
designs,
limited
articles
published
English,
mainly
self-report
questionnaires.
most
prevalent
symptoms,
from
least
reported,
anxiety,
depression,
post-traumatic
stress
disorder
(PTSD),
poor
sleep
qualities,
somatic
cognitive
deficits.
Being
female
having
diagnoses
European Neuropsychopharmacology,
Год журнала:
2022,
Номер
59, С. 82 - 92
Опубликована: Апрель 14, 2022
The
ongoing
Coronavirus
Disease
(COVID-19)
pandemic
has
so
far
affected
more
than
500
million
people.
Lingering
fatigue
and
cognitive
difficulties
are
key
concerns
because
they
impede
productivity
quality
of
life.
However,
the
prevalence
duration
neurocognitive
sequelae
association
with
functional
outcomes
after
COVID-19
unclear.
This
longitudinal
study
explored
frequency,
severity
pattern
impairment
implications
1
year
hospitalisation
its
trajectory
from
3
months
hospitalisation.
Patients
who
had
been
hospitalised
our
previously
published
3-months
at
Copenhagen
University
Hospital
were
re-invited
for
a
1-year
follow-up
assessment
function,
functioning
depression
symptoms.
Twenty-five
29
assessed
patients
(86%)
re-assessed
(11±2
months).
Clinically
significant
impairments
identified
in
48-56
%
depending
on
cut-off,
verbal
learning
executive
function
being
most
severely
affected.
was
comparable
to
frequency
observed
months.
Objectively
measured
scaled
subjective
difficulties,
reduced
work
capacity
poorer
Further,
associated
subsequent
depressive
symptoms
year.
In
conclusion,
stable
approximately
half
hospitalized
negative
functioning,
life
mood
underline
importance
screening
addressing
severe
COVID-19.
Acta Neuropsychiatrica,
Год журнала:
2022,
Номер
34(3), С. 109 - 126
Опубликована: Фев. 11, 2022
Long
COVID
refers
to
the
lingering
symptoms
which
persist
or
appear
after
acute
illness.
The
dominant
long
in
two
years
since
pandemic
began
(2020-2021)
have
been
depression,
anxiety,
fatigue,
concentration
and
cognitive
impairments
with
few
reports
of
psychosis.
Whether
other
will
later
on
is
not
yet
known.
For
example,
dopamine-dependent
movement
disorders
generally
take
many
before
first
are
seen.
Post-stroke
depression
anxiety
may
explain
early
cases.
Hemorrhagic,
hypoxic
inflammatory
damages
central
nervous
system,
unresolved
systematic
inflammation,
metabolic
impairment,
cerebral
vascular
accidents
such
as
stroke,
hypoxia
from
pulmonary
fibrotic
changes
among
major
causes
COVID.
Glucose
brain
issues
likely
predispose
subjects
pre-existing
diabetes,
cardiovascular
lung
problems
well.
Preliminary
data
suggest
that
psychotropic
medications
be
a
danger
but
could
instead
beneficial
combating
COVID-19
infection.
same
true
for
diabetes
metformin.
Thus,
focus
sigma-1
receptor
ligands
glucose
metabolism
expected
useful
new
drug
development
well
repurposing
current
drugs.
reported
protective
effects
psychotropics
antihistamines
against
COVID-19,
earlier
reduced
number
receptors
post-mortem
schizophrenic
brains,
antidepressant
antipsychotic
drugs
being
significant
affinity
receptor,
support
role
sigma
histamine
neuroinflammation
viral
infections.
Literature
all
these
areas
accumulating
at
fast
rate.
We
reviewed
discussed
relevant
important
literature.
Brain Behavior & Immunity - Health,
Год журнала:
2023,
Номер
27, С. 100587 - 100587
Опубликована: Янв. 5, 2023
Subjective
and
objective
cognitive
dysfunction
are
reported
after
COVID-19
but
with
limited
data
on
their
congruence
associations
the
severity
of
acute
disease.
The
aim
this
cohort
study
is
to
describe
prevalence
subjective
at
three
six
months
symptoms
psychological
disease-related
factors.We
assessed
a
184
patients
COVID-19:
82
admitted
Intensive
Care
Unit
(ICU),
53
regular
hospital
wards,
49
isolated
home.
A
non-COVID
control
group
individuals
was
included.
Demographic
clinical
were
collected.
symptoms,
impairment,
depressive
post-traumatic
stress
disorder
(PTSD)
assessed.At
months,
impairment
by
32.3%
ICU-treated,
37.3%
ward-treated,
33.3%
home-isolated
observed
in
36.1%
34.7%
8.9%
patients.
associated
PTSD
female
sex,
not
assessment
or
metrics.One-third
patients,
regardless
disease
severity,
high
levels
which
results
from
screening
demographic
factors.
Our
stresses
importance
thorough
reporting
long-term
for
underlying
mental
health
related
factors
such
as
depression.
PLoS ONE,
Год журнала:
2023,
Номер
18(4), С. e0284075 - e0284075
Опубликована: Апрель 7, 2023
Prolonged
symptoms
of
COVID-19
have
been
found
in
many
patients,
often
known
as
Long
COVID.
Psychiatric
are
commonly
seen
COVID
patients
and
could
last
for
weeks,
even
months,
after
recovery.
However,
the
risk
factors
associated
with
it
remain
unclear.
In
current
systematic
review,
we
provide
an
overview
psychiatric
development
those
symptoms.
Articles
were
systematically
searched
on
SCOPUS,
PubMed,
EMBASE
up
to
October
2021.
Studies
involving
adults
geriatric
participants
a
confirmed
previous
diagnosis
reported
that
persist
more
than
four
weeks
initial
infection
included.
The
bias
was
assessed
using
Newcastle-Ottawa
Scale
(NOS)
observational
studies.
Prevalence
rates
collected.
This
present
study
registered
at
PROSPERO
(CRD42021240776).
total,
23
studies
Several
limitations
this
review
heterogeneity
studies’
outcomes
designs,
limited
articles
published
English,
mainly
self-report
questionnaires.
most
prevalent
symptoms,
from
least
reported,
anxiety,
depression,
post-traumatic
stress
disorder
(PTSD),
poor
sleep
qualities,
somatic
cognitive
deficits.
Being
female
having
diagnoses
