Arabian Journal of Chemistry,
Год журнала:
2024,
Номер
17(10), С. 105968 - 105968
Опубликована: Авг. 17, 2024
Hydrogels
are
three-dimensional
structures
that
serve
as
substitutes
for
the
extracellular
matrix
(ECM)
and
possess
outstanding
physicochemical
biochemical
characteristics.
They
gaining
importance
in
regenerative
medicine
because
of
their
similarity
to
natural
terms
moisture
content
wound
tissue
healing
permeability.
Tissue
engineering
advancements
have
resulted
development
flexible
hydrogels
mimic
dynamic
characteristics
ECM.
Several
approaches
been
applied
produce
from
biopolymers
with
enhanced
functional
structural
different
applications
(TERM).
This
review
provides
a
comprehensive
overview
hydrogel
healing,
engineering,
drug
delivery
systems.
We
outline
types
based
on
physical
chemical
crosslinking,
fundamental
properties,
TERM.
article
provided
recent
literature
within
five
years.
Recent
developments
biopolymer-based
state-of-the-art
discussed,
emphasizing
significant
challenges
future
perspectives.
Bioactive Materials,
Год журнала:
2022,
Номер
24, С. 197 - 235
Опубликована: Дек. 23, 2022
Chronic
wounds
have
become
one
of
the
most
important
issues
for
healthcare
systems
and
are
a
leading
cause
death
worldwide.
Wound
dressings
necessary
to
facilitate
wound
treatment.
Engineering
may
substantially
reduce
healing
time,
risk
recurrent
infections,
disability
costs
associated.
In
path
engineering
an
ideal
dressing,
hydrogels
played
role.
Hydrogels
3D
hydrophilic
polymeric
structures
that
can
provide
protective
barrier,
mimic
native
extracellular
matrix
(ECM),
humid
environment.
Due
their
advantages,
(with
different
architectural,
physical,
mechanical,
biological
properties)
been
extensively
explored
as
dressing
platforms.
Here
we
describe
recent
studies
on
applications
with
strong
focus
interplay
between
fabrication
method
used
performance
achieved.
Moreover,
review
categories
additives
which
enhance
regeneration
using
hydrogel
dressings.
Hydrogel
promises
generation
smart
solutions
solve
this
pressing
problem,
enabling
key
functionalities
such
bacterial
growth
inhibition,
enhanced
re-epithelialization,
vascularization,
improved
recovery
tissue
functionality,
overall,
accelerated
effective
healing.
ACS Nano,
Год журнала:
2023,
Номер
17(11), С. 9681 - 9693
Опубликована: Май 18, 2023
Hydrogels
have
emerged
as
promising
materials
for
flexible
electronics
due
to
their
unique
properties,
such
high
water
content,
softness,
and
biocompatibility.
In
this
perspective,
we
provide
an
overview
of
the
development
hydrogels
electronics,
with
a
focus
on
three
key
aspects:
mechanical
interfacial
adhesion,
conductivity.
We
discuss
principles
designing
high-performance
present
representative
examples
potential
applications
in
field
healthcare.
Despite
significant
progress,
several
challenges
remain,
including
improving
antifatigue
capability,
enhancing
balancing
content
wet
environments.
Additionally,
highlight
importance
considering
hydrogel-cell
interactions
dynamic
properties
future
research.
Looking
ahead,
is
promising,
exciting
opportunities
horizon,
but
continued
investment
research
necessary
overcome
remaining
challenges.
The
overuse
of
antibiotics
for
treating
bacterial
infection
has
caused
severe
resistance
and
become
a
public
health
threat
worldwide.
It
is
desired
to
develop
novel
antibiotic
delivery
systems
as
efficient
antibacterial
strategies
promoting
anti-infective
therapy.
Herein,
the
AgNPs-loaded
Advanced Functional Materials,
Год журнала:
2023,
Номер
34(1)
Опубликована: Сен. 19, 2023
Abstract
Conductive
hydrogels
(CHs)
for
flexible
bioelectronic
devices
have
raised
great
attention
due
to
their
tunable
mechanical
performances,
adhesion,
anti‐swelling,
and
biocompatibility.
This
review
summarizes
the
current
development
of
conductive
hydrogel‐based
in
aspect
classifications
applications.
Firstly,
are
classified
into
two
kinds
according
types
conductivity:
ionic
electronic
(hydrogel
based
on
pure
materials,
introducing
micro/nano‐materials).
Secondly,
applications
device,
like
wearable
(strain
sensor,
body
fluid
detector,
serviced
extreme
environment),
tissue
engineering
(skin,
heart,
nerve,
muscle),
other
(bionic
robot,
cancer
treatment),
highly
illustrated.
Finally,
a
depth
outlook
is
given,
which
aims
promote
this
field
future.
Chemical Science,
Год журнала:
2023,
Номер
14(12), С. 3091 - 3116
Опубликована: Янв. 1, 2023
This
work
reviewed
the
new
progress
of
conductive
hydrogels
in
application
tissue
repair
and
provided
a
useful
reference
for
further
preparation
safer
more
efficient
engineering.
Advanced Functional Materials,
Год журнала:
2023,
Номер
33(10)
Опубликована: Янв. 1, 2023
Abstract
Diabetic
foot
ulcer
(DFU)
is
one
of
the
most
common
complications
diabetes,
bringing
physical
and
mental
challenges
for
patients
due
to
lack
efficient
curative
therapy.
Despite
considerable
advances
in
pharmacological
surgical
approaches,
clinical
trials
DFU
remain
disappointing
local
overactive
excessive
inflammation.
Immunomodulatory
hydrogels
has
significant
advantages
overcome
challenge
DFUs
Here,
recent
fabrication
regenerative
utilization
functional
altering
immune
microenvironment
are
comprehensively
reviewed.
The
pathological
features
healing
processes
DFUs,
followed
by
summarizing
physicochemical
properties
essential
design
immunomodulation
briefly
introduced.
Then,
potential
immuno‐therapeutic
modalities
emerging
trends
used
treat
via
multitherapeutic
approaches
enhanced
efficacy
safety
discussed.
Taken
together,
linking
structural
their
functions
therapy
with
a
particular
focus
on
immunomodulatory
stimuli,
this
review
can
promote
further
designing
advanced
resulting
improved
diabetic
wound
repair
through
translation
into
setting
near
future.
Materials Today Bio,
Год журнала:
2023,
Номер
19, С. 100589 - 100589
Опубликована: Фев. 23, 2023
The
skin
is
one
of
the
most
essential
organs
in
human
body,
interacting
with
external
environment
and
shielding
body
from
diseases
excessive
water
loss.
Thus,
loss
integrity
large
portions
due
to
injury
illness
may
lead
significant
disabilities
even
death.
Decellularized
biomaterials
derived
extracellular
matrix
tissues
are
natural
quantities
bioactive
macromolecules
peptides,
which
possess
excellent
physical
structures
sophisticated
biomolecules,
thus,
promote
wound
healing
regeneration.
Here,
we
highlighted
applications
decellularized
materials
repair.
First,
wound-healing
process
was
reviewed.
Second,
elucidated
mechanisms
several
constitutes
facilitating
healing.
Third,
major
categories
treatment
cutaneous
wounds
numerous
preclinical
models
over
decades
clinical
practice
were
elaborated.
Finally,
discussed
current
hurdles
field
anticipated
future
challenges
novel
avenues
for
research
on
biomaterials-based
treatment.
Chemical Reviews,
Год журнала:
2023,
Номер
123(24), С. 14084 - 14118
Опубликована: Ноя. 16, 2023
Bioadhesives
have
emerged
as
transformative
and
versatile
tools
in
healthcare,
offering
the
ability
to
attach
tissues
with
ease
minimal
damage.
These
materials
present
numerous
opportunities
for
tissue
repair
biomedical
device
integration,
creating
a
broad
landscape
of
applications
that
captivated
clinical
scientific
interest
alike.
However,
fully
unlocking
their
potential
requires
multifaceted
design
strategies
involving
optimal
adhesion,
suitable
biological
interactions,
efficient
signal
communication.
In
this
Review,
we
delve
into
these
pivotal
aspects
bioadhesive
design,
highlight
latest
advances
applications,
identify
lie
ahead
bioadhesives
multifunctional
technology
platforms.
