Emerging contaminants: A One Health perspective

The Innovation, Год журнала: 2024, Номер 5(4), С. 100612 - 100612

Опубликована: Март 13, 2024

Язык: Английский

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Nanozyme-enhanced paper-based biosensor technologies

TrAC Trends in Analytical Chemistry, Год журнала: 2024, Номер 172, С. 117573 - 117573

Опубликована: Фев. 9, 2024

Nanozymes, enzyme-mimetic nanomaterials that combine features of nanoscale material with the catalytic properties enzymes, have undergone rapid development in recent years. While enzymes remained integral to biosensor technologies for past few decades, potential nanozymes overcome low stability and high production costs biological is turning them into promising candidates. Over decade, been explored a myriad biosensing applications. However, only small subset these efforts has resulted devices platforms are potentially suitable on-site/point-of-care monitoring. To promote this area, review first provides concise overview different paper-based technologies, their architecture functionality, language conducive nanozyme research community. The review, then, critically discusses progress made integration on-site detection food contaminants, environmental pollutants, disease biomarkers. challenges associated transition solution-based biosensors relevant highlighted, strategies those proposed. We envision could narrow gap impeding translation nanozyme-based from laboratories real-world scenarios by encouraging consolidated cross-disciplinary trans-sectoral efforts.

Язык: Английский

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Recent Progress and Prospect of Metal–Organic Framework-Based Nanozymes in Biomedical Application

Nanomaterials, Год журнала: 2024, Номер 14(3), С. 244 - 244

Опубликована: Янв. 23, 2024

A nanozyme is a nanoscale material having enzyme-like properties. It exhibits several superior properties, including low preparation cost, robust catalytic activity, and long-term storage at ambient temperatures. Moreover, high stability enables repetitive use in multiple reactions. Hence, it considered potential replacement for natural enzymes. Enormous research interest nanozymes the past two decades has made imperative to look better enzyme-mimicking materials biomedical applications. Given this, on metal–organic frameworks (MOFs) as gained momentum. MOFs are advanced hybrid of inorganic metal ions organic ligands. Their distinct composition, adaptable pore size, structural diversity, ease tunability physicochemical properties enable mimic activities act promising candidates. This review aims discuss recent advances development MOF-based (MOF-NZs) highlight their applications field biomedicine. Firstly, different enzyme-mimetic exhibited by discussed, insights given into various strategies achieve them. Modification functionalization deliberated obtain MOF-NZs with enhanced activity. Subsequently, biosensing therapeutics domain discussed. Finally, concluded giving challenges encountered possible directions overcome them future. With this review, we aim encourage consolidated efforts across enzyme engineering, nanotechnology, science, biomedicine disciplines inspire exciting innovations emerging yet field.

Язык: Английский

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Plasmonic nanoparticle sensors: current progress, challenges, and future prospects

Nanoscale Horizons, Год журнала: 2024, Номер 9(12), С. 2085 - 2166

Опубликована: Янв. 1, 2024

This comprehensive review summarizes the past, present, and future of plasmonic NP-based sensors in terms different sensing platforms, chemical biological analytes, expected technologies.

Язык: Английский

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Advancing the impact of plant biostimulants to sustainable agriculture through nanotechnologies

Chemical and Biological Technologies in Agriculture, Год журнала: 2023, Номер 10(1)

Опубликована: Окт. 24, 2023

Abstract Nanomaterials and plant biostimulants are attracting significant attention for their potential applications in the agri-food sector. These efforts have mostly focused on independent applicability of these two emerging fields to achieve improved agricultural outcomes. However, an even larger impact can be created if nanotechnology biostimulant technology combined. This transdisciplinary review combines diverse highlight role nanotechnologies advancing sustainable production high-quality food. The first explains key concepts a tutorial style offer research community understanding nanotechnology. then dives deeply into which substances or microorganisms complex mixtures capable improving nutrition growth, directly influencing aspects relevant food quality, safety, security. presents convincing case that combining nanomaterials with provides promising answer against insecurity near future. Sustainability is central our discussions, exemplified by cases, such as from waste material, thus contributing circular economy. also identifies avenues utilize value biostimulants. Strategies nanoencapsulation proposed produce nano-biostimulants could act synergistically enhance quality while offering solution increasing challenge respecting environment. Graphical

Язык: Английский

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Electrochemical aptasensor based on CRISPR/Cas12a-mediated and DNAzyme-assisted cascade dual-enzyme transformation strategy for zearalenone detection

Chemical Engineering Journal, Год журнала: 2024, Номер 493, С. 152431 - 152431

Опубликована: Май 24, 2024

Язык: Английский

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Biosensor Technologies for Water Quality: Detection of Emerging Contaminants and Pathogens

Biosensors, Год журнала: 2025, Номер 15(3), С. 189 - 189

Опубликована: Март 15, 2025

This review explores the development, technological foundations, and applications of biosensor technologies across various fields, such as medicine for disease diagnosis monitoring, food industry. However, primary focus is on their use in detecting contaminants pathogens, well environmental monitoring water quality assessment. The classifies different types biosensors based bioreceptor transducer, highlighting how they are specifically designed detection emerging (ECs) pathogens water. Key innovations this technology critically examined, including advanced techniques systematic evolution ligands by exponential enrichment (SELEX), molecularly imprinted polymers (MIPs), self-assembled monolayers (SAMs), which enable fabrication sensors with improved sensitivity selectivity. Additionally, integration microfluidic systems into analyzed, demonstrating significant enhancements performance speed. Through these advancements, work emphasizes fundamental role key tools safeguarding public health preserving integrity.

Язык: Английский

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Enrofloxacin Rapid Detection in Aquatic Foods: Based on DNA Aptamer Sensor

Foods, Год журнала: 2024, Номер 13(6), С. 941 - 941

Опубликована: Март 20, 2024

Enrofloxacin (ENR) is widely used as a synthetic fluoroquinolone antibiotic for disease control in aquatic animals. ENR aptamers were screened this study using the magnetic bead-SELEX method, and graphene oxide fluorescent sensor was developed to detect residues products. Firstly, conjugated amino beads by amidation reaction, then aptamer sequences showing high affinity step SELEX screening method. Finally, after 10 rounds of screening, six candidate with obtained. Among these, ENR-Apt 6 selected based on its secondary structure features, (

Язык: Английский

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The Fabrication of a Probe-Integrated Electrochemiluminescence Aptasensor Based on Double-Layered Nanochannel Array with Opposite Charges for the Sensitive Determination of C-Reactive Protein

Molecules, Год журнала: 2023, Номер 28(23), С. 7867 - 7867

Опубликована: Ноя. 30, 2023

The effective and sensitive detection of the important biomarker, C-reactive protein (CRP), is great significance in clinical diagnosis. development a convenient highly electrochemiluminescence (ECL) aptasensor with an immobilized emitter probe desirable. In this work, probe-integrated ECL aptamer sensor was constructed based on bipolar silica nanochannel film (bp-SNF) modified electrode for CRP. bp-SNF, ITO electrode, consisted dual-layered SNF film, including negatively charged inner (n-SNF) outer positive charge amino groups (p-SNF). emitter, tris(bipyridine) ruthenium (II) (Ru(bpy)32+), stably bp-SNF using dual electrostatic interactions n-SNF attracting p-SNF repelling. surface were aldehyde derivatized, allowing covalent immobilization recognitive aptamers (5′-NH2-CGAAGGGGATTCGAGGGGTGATTGCGTGCTCCATTTGGTG-3′), leading to recognition interface. When CRP bound interface, formed complex increased interface resistance reduced diffusion co-reactant tripropylamine (TPA) into nanochannels, decrease signal. Based mechanism, could achieve ranging from 0.01 1000 ng/mL, limit (DL) 8.5 pg/mL. method constructing simple, it offers high stability, good selectivity, sensitivity.

Язык: Английский

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Multivariate Optimization of Electrochemical Biosensors for the Determination of Compounds Related to Food Safety—A Review

Biosensors, Год журнала: 2023, Номер 13(7), С. 694 - 694

Опубликована: Июнь 30, 2023

We summarize the application of multivariate optimization for construction electrochemical biosensors. The introduction provides an overview biosensing, which is classified into catalytic-based and affinity-based biosensors, discusses most recent published works in each category. then explore relevance biosensors food safety analysis, taking account analytes different natures. Then, we describe chemometrics tools used sensors/biosensors provide examples from literature. Finally, carefully discuss based on design experiments, including advantages, disadvantages, future perspectives using this field. discussion section offers a comprehensive analysis these topics.

Язык: Английский

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