Social 'envirotyping' the ABCD study contextualizes dissociable brain organization and diverging outcomes DOI Creative Commons

Haily Merritt,

Mary Kate Koch,

Youngheun Jo

и другие.

bioRxiv (Cold Spring Harbor Laboratory), Год журнала: 2024, Номер unknown

Опубликована: Авг. 22, 2024

The environment, especially social features, plays a key role in shaping the development of brain, notably during adolescence. To better understand variation brain-environment coupling and its associated outcomes, we identified ''envirotypes,'' or different patterns environment experience, Adolescent Brain Cognitive Development Study by hierarchically clustering subjects. Two focal clusters, which accounted for 89.3% all participants, differed significantly on eight out nine youth-report quality measures, representing almost perfect complements. We then applied tools from network neuroscience to show envirotypes are with whole brain functional connectivity. Differences were distributed across but prominent Default Somatomotor Hand systems these clusters. Finally, examined how change over suite outcomes. resulting dynamic along dimensions stability quality, outcomes diverged based stability. Specifically, stable, high envirotype was most easily distinguished improving envirotype, while unstable worst Altogether, our findings represent significant contributions both developmental neuroscience, emphasizing variability dynamicity consequences.

Язык: Английский

Childhood socioeconomic status and the pace of structural neurodevelopment: accelerated, delayed, or simply different? DOI Creative Commons
Divyangana Rakesh, Sarah Whittle, Margaret A. Sheridan

и другие.

Trends in Cognitive Sciences, Год журнала: 2023, Номер 27(9), С. 833 - 851

Опубликована: Май 11, 2023

Socioeconomic status (SES) is associated with children's brain and behavioral development. Several theories propose that early experiences of adversity or low SES can alter the pace neurodevelopment during childhood adolescence. These make contrasting predictions about whether adverse are accelerated delayed neurodevelopment. We contextualize these within context normative development cortical subcortical structure review existing evidence on structural to adjudicate between competing hypotheses. Although none fully consistent observed SES-related differences in development, suggests trajectories more a simply different developmental pattern than an acceleration

Язык: Английский

Процитировано

73

Assessment of Parent Income and Education, Neighborhood Disadvantage, and Child Brain Structure DOI Creative Commons
Divyangana Rakesh, Andrew Zalesky, Sarah Whittle

и другие.

JAMA Network Open, Год журнала: 2022, Номер 5(8), С. e2226208 - e2226208

Опубликована: Авг. 18, 2022

Importance

Although different aspects of socioeconomic status (SES) may represent distinct risk factors for poor mental health in children, knowledge their differential and synergistic associations with the brain is limited.

Objective

To examine independent between SES child structure.

Design, Setting, Participants

We used baseline data from participants aged 9 to 10 years Adolescent Brain Cognitive Development (ABCD) study. These were collected 21 US sites September 2017 August 2018. Study recruited schools create a participant sample that closely reflects population.

Exposures

Neighborhood disadvantage was measured using area deprivation index. also on total parent or caregiver educational attainment (in years) household income-to-needs ratio.

Main Outcomes Measures

T1-weighted magnetic resonance imaging assess measures cortical thickness, surface area, subcortical volume.

Results

Data 8862 ABCD analyzed. The mean (SD) age 119.1 (7.5) months; there 4243 girls (47.9%) 4619 boys (52.1%). race ethnicity available 8857 participants: 173 (2.0%) Asian, 1099 (12.4%) Black African American, 1688 (19.1%) Hispanic, 4967 (56.1%) White, 930 (10.5%) reported multiple races ethnicities. Using 10-fold, within-sample split-half replication, we found neighborhood associated lower thickness following regions (η2 = 0.004-0.009): cuneus (B[SE] −0.099 [0.013];P < .001), lateral occipital (B [SE] −0.088 [0.011];P orbitofrontal −0.072 [0.012];P lingual −0.104 paracentral −0.086 pericalcarine −0.077 postcentral −0.069 precentral −0.059 rostral middle frontal −0.076 superior parietal −0.060 .001). Exploratory analyses showed low attenuated presence high ratio 0.003-0.007).

Conclusions Relevance

findings this cross-sectional study suggest indicators have children’s A play protective role context attainment. This highlights importance considering joint future work.

Язык: Английский

Процитировано

64

Environmental contributions to cognitive development: The role of cognitive stimulation DOI Creative Commons
Divyangana Rakesh, Katie A. McLaughlin, Margaret A. Sheridan

и другие.

Developmental Review, Год журнала: 2024, Номер 73, С. 101135 - 101135

Опубликована: Июнь 12, 2024

Early environmental experiences influence children's cognitive and neural development. In particular, stimulation, defined as inputs that engage the senses provide learning opportunities for children, fosters acquisition of knowledge across various domains. Low levels stimulation in early life may restrict opportunities, contributing to lasting consequences development later academic occupational achievement. This review delves into role related performance, available tools measuring settings, offers insights future research directions. addition, variability often linked differences socioeconomic status, create disparities access enriching foundation learning. We therefore briefly status also leverage evidence from intervention studies illustrate importance outcomes. Investigating on brain behavior is crucial developing effective strategies foster healthy all children unlocking their full potential.

Язык: Английский

Процитировано

16

Relations of temporoparietal connectivity with neighborhood social fragmentation in youth at clinical high-risk for psychosis DOI
Katrina Aberizk, Esra Sefik, Qingyue Yuan

и другие.

Schizophrenia Research, Год журнала: 2025, Номер 277, С. 151 - 158

Опубликована: Март 1, 2025

Язык: Английский

Процитировано

2

Aspects of Area Deprivation Index in Relation to Hippocampal Volume Among Children DOI Creative Commons
Benson S. Ku, Katrina Aberizk, Cope Feurer

и другие.

JAMA Network Open, Год журнала: 2024, Номер 7(6), С. e2416484 - e2416484

Опубликована: Июнь 12, 2024

Area deprivation index (ADI) has been shown to be associated with reduced hippocampal volume (HV) among youths. The social environment may interact the association between ADI and HV.

Язык: Английский

Процитировано

8

Environmental and neurodevelopmental contributors to youth mental illness DOI Creative Commons
Sarah Whittle, Lu Zhang, Divyangana Rakesh

и другие.

Neuropsychopharmacology, Год журнала: 2024, Номер 50(1), С. 201 - 210

Опубликована: Июль 19, 2024

Abstract While a myriad of factors likely contribute to the development mental illness in young people, social environment (including early adverse experiences) concert with neurodevelopmental alterations is undeniably important. A number influential theories make predictions about how and why may mediate or moderate effects on emergence illness. Here, we discuss current evidence supporting each these theories. Although this area research rapidly growing, body still relatively limited. However, there exist some consistent findings, including increased striatal reactivity during positive affective processing larger hippocampal volumes being associated vulnerability susceptibility environments internalizing symptoms. Limited longitudinal work has investigated mechanisms linking health. Drawing from human insights animal studies, propose an integrated mediation-moderation model outline future directions advance field.

Язык: Английский

Процитировано

7

Associations between socioeconomic status and mental health trajectories during early adolescence: Findings from the Adolescent Brain Cognitive Development study DOI Creative Commons
Divyangana Rakesh, John C. Flournoy, Katie A. McLaughlin

и другие.

JCPP Advances, Год журнала: 2025, Номер unknown

Опубликована: Фев. 25, 2025

Abstract Background Low socioeconomic status (SES) during childhood is associated with higher levels of youth psychopathology. However, limited longitudinal work has examined the role both household and neighborhood SES in shaping mental health trajectories over time using population‐based data. The goal present study was to characterize associations between changes problems early adolescence. Methods We investigated independent joint income‐to‐needs ratio, parent educational attainment, material hardship, disadvantage internalizing, externalizing, attention symptom data from Adolescent Brain Cognitive Development (ABCD) Study. Given sex‐based differences ABCD study, analyses were conducted separately males females. assessed at baseline youth‐reported across six time‐points age 10–13 years ( M = 10.4, SD 0.63 years; first 6‐month follow‐up; N 9488). Results Main effects indicated that, general, high lower symptoms. longitudinally, increases relative SES. In females, while internalizing symptoms increased all income‐to‐needs, association most positive B 0.036, SE 0.008, p < 0.001). males, positively predicted externalizing 0.022, 0.007, 0.002) 0.023, 0.001) trajectories, linked income‐to‐needs. Two‐way interactions indicators predicting non‐significant. Conclusion Our finding that lower‐SES backgrounds exhibited adolescence contrasts findings prior cross‐sectional studies. are on rise landscape risk for psychopathology changing. More research needed understand how contributes resilience transition

Язык: Английский

Процитировано

1

Associations of socioeconomic status with cognitive function, language ability, and academic achievement in youth: a systematic review of mechanisms and protective factors DOI Creative Commons
Divyangana Rakesh, Paul Lee,

Avinash J. Gaikwad

и другие.

Journal of Child Psychology and Psychiatry, Год журнала: 2024, Номер unknown

Опубликована: Дек. 3, 2024

Low socioeconomic status (SES) is negatively associated with children's cognitive and academic performance, leading to long‐term educational economic disparities. In particular, SES a powerful predictor of executive function (EF), language ability, achievement. Despite extensive research documenting SES‐related differences in these domains, our understanding the mechanisms underlying associations factors that may mitigate relationships limited. This systematic review aimed identify mediators moderators association EF, Our synthesis revealed stress, support, stimulation, broader contextual at school‐ neighborhood level be important protective associations. stimulation mediated Educational expectations, classroom school environment, teacher–student also played key role addition, such as preschool attendance, home learning activities, parental support buffered between low lower outcomes. We discuss findings context interventions help reduce

Язык: Английский

Процитировано

4

Adolescent resilience in the face of COVID-19 stressors: the role of trauma and protective factors DOI Creative Commons
Lu Zhang, Vanessa Cropley, Sarah Whittle

и другие.

Psychological Medicine, Год журнала: 2024, Номер 54(13), С. 3667 - 3677

Опубликована: Окт. 1, 2024

Abstract Background The COVID-19 pandemic introduced unique stressors that posed significant threats to adolescent mental health. However, limited research has examined the impact of trauma exposure on vulnerability subsequent stressor-related health outcomes in adolescents. Furthermore, it is unclear whether there are protective factors promote resilience against negative impacts adolescents with prior exposure. This preregistered study aimed investigate difficulties adolescents, addition role factors. Methods Aims were investigated a sample 9696 (mean age 12.85 ± 0.88 years) from Adolescent Brain Cognitive Development Study. Linear mixed-effects models employed examine (a) associations early (exposed v. non-exposed), stressors, and perceived stress, sadness, positive affect levels during period US, (b) (physical activity, parental support, improvements family peer relationships) these associations. Results There was association between which enhanced trauma-exposed Improvements relationships mitigated poor outcomes, regardless traumatic experience. Conclusions These findings support hypothesis elevates risk face future stressors. underscore social as targets for prevention intervention those experiencing acute experiences.

Язык: Английский

Процитировано

3

The connecting brain in context: How adolescent plasticity supports experiential learning and development DOI Creative Commons
Amanda E. Baker, Adriana Galván, Andrew J. Fuligni

и другие.

Developmental Cognitive Neuroscience, Год журнала: 2024, Номер 71, С. 101486 - 101486

Опубликована: Ноя. 28, 2024

Язык: Английский

Процитировано

3