bioRxiv (Cold Spring Harbor Laboratory),
Год журнала:
2024,
Номер
unknown
Опубликована: Авг. 22, 2024
The
environment,
especially
social
features,
plays
a
key
role
in
shaping
the
development
of
brain,
notably
during
adolescence.
To
better
understand
variation
brain-environment
coupling
and
its
associated
outcomes,
we
identified
''envirotypes,''
or
different
patterns
environment
experience,
Adolescent
Brain
Cognitive
Development
Study
by
hierarchically
clustering
subjects.
Two
focal
clusters,
which
accounted
for
89.3%
all
participants,
differed
significantly
on
eight
out
nine
youth-report
quality
measures,
representing
almost
perfect
complements.
We
then
applied
tools
from
network
neuroscience
to
show
envirotypes
are
with
whole
brain
functional
connectivity.
Differences
were
distributed
across
but
prominent
Default
Somatomotor
Hand
systems
these
clusters.
Finally,
examined
how
change
over
suite
outcomes.
resulting
dynamic
along
dimensions
stability
quality,
outcomes
diverged
based
stability.
Specifically,
stable,
high
envirotype
was
most
easily
distinguished
improving
envirotype,
while
unstable
worst
Altogether,
our
findings
represent
significant
contributions
both
developmental
neuroscience,
emphasizing
variability
dynamicity
consequences.
Trends in Cognitive Sciences,
Год журнала:
2023,
Номер
27(9), С. 833 - 851
Опубликована: Май 11, 2023
Socioeconomic
status
(SES)
is
associated
with
children's
brain
and
behavioral
development.
Several
theories
propose
that
early
experiences
of
adversity
or
low
SES
can
alter
the
pace
neurodevelopment
during
childhood
adolescence.
These
make
contrasting
predictions
about
whether
adverse
are
accelerated
delayed
neurodevelopment.
We
contextualize
these
within
context
normative
development
cortical
subcortical
structure
review
existing
evidence
on
structural
to
adjudicate
between
competing
hypotheses.
Although
none
fully
consistent
observed
SES-related
differences
in
development,
suggests
trajectories
more
a
simply
different
developmental
pattern
than
an
acceleration
JAMA Network Open,
Год журнала:
2022,
Номер
5(8), С. e2226208 - e2226208
Опубликована: Авг. 18, 2022
Importance
Although
different
aspects
of
socioeconomic
status
(SES)
may
represent
distinct
risk
factors
for
poor
mental
health
in
children,
knowledge
their
differential
and
synergistic
associations
with
the
brain
is
limited.
Objective
To
examine
independent
between
SES
child
structure.
Design,
Setting,
Participants
We
used
baseline
data
from
participants
aged
9
to
10
years
Adolescent
Brain
Cognitive
Development
(ABCD)
study.
These
were
collected
21
US
sites
September
2017
August
2018.
Study
recruited
schools
create
a
participant
sample
that
closely
reflects
population.
Exposures
Neighborhood
disadvantage
was
measured
using
area
deprivation
index.
also
on
total
parent
or
caregiver
educational
attainment
(in
years)
household
income-to-needs
ratio.
Data
8862
ABCD
analyzed.
The
mean
(SD)
age
119.1
(7.5)
months;
there
4243
girls
(47.9%)
4619
boys
(52.1%).
race
ethnicity
available
8857
participants:
173
(2.0%)
Asian,
1099
(12.4%)
Black
African
American,
1688
(19.1%)
Hispanic,
4967
(56.1%)
White,
930
(10.5%)
reported
multiple
races
ethnicities.
Using
10-fold,
within-sample
split-half
replication,
we
found
neighborhood
associated
lower
thickness
following
regions
(η2
=
0.004-0.009):
cuneus
(B[SE]
−0.099
[0.013];P
<
.001),
lateral
occipital
(B
[SE]
−0.088
[0.011];P
orbitofrontal
−0.072
[0.012];P
lingual
−0.104
paracentral
−0.086
pericalcarine
−0.077
postcentral
−0.069
precentral
−0.059
rostral
middle
frontal
−0.076
superior
parietal
−0.060
.001).
Exploratory
analyses
showed
low
attenuated
presence
high
ratio
0.003-0.007).
Conclusions
Relevance
findings
this
cross-sectional
study
suggest
indicators
have
children’s
A
play
protective
role
context
attainment.
This
highlights
importance
considering
joint
future
work.
Developmental Review,
Год журнала:
2024,
Номер
73, С. 101135 - 101135
Опубликована: Июнь 12, 2024
Early
environmental
experiences
influence
children's
cognitive
and
neural
development.
In
particular,
stimulation,
defined
as
inputs
that
engage
the
senses
provide
learning
opportunities
for
children,
fosters
acquisition
of
knowledge
across
various
domains.
Low
levels
stimulation
in
early
life
may
restrict
opportunities,
contributing
to
lasting
consequences
development
later
academic
occupational
achievement.
This
review
delves
into
role
related
performance,
available
tools
measuring
settings,
offers
insights
future
research
directions.
addition,
variability
often
linked
differences
socioeconomic
status,
create
disparities
access
enriching
foundation
learning.
We
therefore
briefly
status
also
leverage
evidence
from
intervention
studies
illustrate
importance
outcomes.
Investigating
on
brain
behavior
is
crucial
developing
effective
strategies
foster
healthy
all
children
unlocking
their
full
potential.
JAMA Network Open,
Год журнала:
2024,
Номер
7(6), С. e2416484 - e2416484
Опубликована: Июнь 12, 2024
Area
deprivation
index
(ADI)
has
been
shown
to
be
associated
with
reduced
hippocampal
volume
(HV)
among
youths.
The
social
environment
may
interact
the
association
between
ADI
and
HV.
Neuropsychopharmacology,
Год журнала:
2024,
Номер
50(1), С. 201 - 210
Опубликована: Июль 19, 2024
Abstract
While
a
myriad
of
factors
likely
contribute
to
the
development
mental
illness
in
young
people,
social
environment
(including
early
adverse
experiences)
concert
with
neurodevelopmental
alterations
is
undeniably
important.
A
number
influential
theories
make
predictions
about
how
and
why
may
mediate
or
moderate
effects
on
emergence
illness.
Here,
we
discuss
current
evidence
supporting
each
these
theories.
Although
this
area
research
rapidly
growing,
body
still
relatively
limited.
However,
there
exist
some
consistent
findings,
including
increased
striatal
reactivity
during
positive
affective
processing
larger
hippocampal
volumes
being
associated
vulnerability
susceptibility
environments
internalizing
symptoms.
Limited
longitudinal
work
has
investigated
mechanisms
linking
health.
Drawing
from
human
insights
animal
studies,
propose
an
integrated
mediation-moderation
model
outline
future
directions
advance
field.
Abstract
Background
Low
socioeconomic
status
(SES)
during
childhood
is
associated
with
higher
levels
of
youth
psychopathology.
However,
limited
longitudinal
work
has
examined
the
role
both
household
and
neighborhood
SES
in
shaping
mental
health
trajectories
over
time
using
population‐based
data.
The
goal
present
study
was
to
characterize
associations
between
changes
problems
early
adolescence.
Methods
We
investigated
independent
joint
income‐to‐needs
ratio,
parent
educational
attainment,
material
hardship,
disadvantage
internalizing,
externalizing,
attention
symptom
data
from
Adolescent
Brain
Cognitive
Development
(ABCD)
Study.
Given
sex‐based
differences
ABCD
study,
analyses
were
conducted
separately
males
females.
assessed
at
baseline
youth‐reported
across
six
time‐points
age
10–13
years
(
M
=
10.4,
SD
0.63
years;
first
6‐month
follow‐up;
N
9488).
Results
Main
effects
indicated
that,
general,
high
lower
symptoms.
longitudinally,
increases
relative
SES.
In
females,
while
internalizing
symptoms
increased
all
income‐to‐needs,
association
most
positive
B
0.036,
SE
0.008,
p
<
0.001).
males,
positively
predicted
externalizing
0.022,
0.007,
0.002)
0.023,
0.001)
trajectories,
linked
income‐to‐needs.
Two‐way
interactions
indicators
predicting
non‐significant.
Conclusion
Our
finding
that
lower‐SES
backgrounds
exhibited
adolescence
contrasts
findings
prior
cross‐sectional
studies.
are
on
rise
landscape
risk
for
psychopathology
changing.
More
research
needed
understand
how
contributes
resilience
transition
Journal of Child Psychology and Psychiatry,
Год журнала:
2024,
Номер
unknown
Опубликована: Дек. 3, 2024
Low
socioeconomic
status
(SES)
is
negatively
associated
with
children's
cognitive
and
academic
performance,
leading
to
long‐term
educational
economic
disparities.
In
particular,
SES
a
powerful
predictor
of
executive
function
(EF),
language
ability,
achievement.
Despite
extensive
research
documenting
SES‐related
differences
in
these
domains,
our
understanding
the
mechanisms
underlying
associations
factors
that
may
mitigate
relationships
limited.
This
systematic
review
aimed
identify
mediators
moderators
association
EF,
Our
synthesis
revealed
stress,
support,
stimulation,
broader
contextual
at
school‐
neighborhood
level
be
important
protective
associations.
stimulation
mediated
Educational
expectations,
classroom
school
environment,
teacher–student
also
played
key
role
addition,
such
as
preschool
attendance,
home
learning
activities,
parental
support
buffered
between
low
lower
outcomes.
We
discuss
findings
context
interventions
help
reduce
Psychological Medicine,
Год журнала:
2024,
Номер
54(13), С. 3667 - 3677
Опубликована: Окт. 1, 2024
Abstract
Background
The
COVID-19
pandemic
introduced
unique
stressors
that
posed
significant
threats
to
adolescent
mental
health.
However,
limited
research
has
examined
the
impact
of
trauma
exposure
on
vulnerability
subsequent
stressor-related
health
outcomes
in
adolescents.
Furthermore,
it
is
unclear
whether
there
are
protective
factors
promote
resilience
against
negative
impacts
adolescents
with
prior
exposure.
This
preregistered
study
aimed
investigate
difficulties
adolescents,
addition
role
factors.
Methods
Aims
were
investigated
a
sample
9696
(mean
age
12.85
±
0.88
years)
from
Adolescent
Brain
Cognitive
Development
Study.
Linear
mixed-effects
models
employed
examine
(a)
associations
early
(exposed
v.
non-exposed),
stressors,
and
perceived
stress,
sadness,
positive
affect
levels
during
period
US,
(b)
(physical
activity,
parental
support,
improvements
family
peer
relationships)
these
associations.
Results
There
was
association
between
which
enhanced
trauma-exposed
Improvements
relationships
mitigated
poor
outcomes,
regardless
traumatic
experience.
Conclusions
These
findings
support
hypothesis
elevates
risk
face
future
stressors.
underscore
social
as
targets
for
prevention
intervention
those
experiencing
acute
experiences.
