Macromol—A Journal of Macromolecular Research,
Год журнала:
2023,
Номер
3(3), С. 431 - 450
Опубликована: Июль 3, 2023
The
use
of
biodegradable
polymers
in
tissue
engineering
has
been
widely
researched
due
to
their
ability
degrade
and
release
components
a
controlled
manner,
allowing
for
the
potential
regeneration
tissues.
Melt
blending
is
common
method
controlling
degradation
rate
these
polymers,
which
involves
combining
materials
molten
state
create
homogenous
mixture
with
tailored
properties.
In
this
study,
polycaprolactone
(PCL)
was
melt
blended
hydrophilic
poly
(ethylene
oxide)
(PEO)
different
molecular
weights
assess
its
effect
on
PCL
material
performance.
Hydrolytic
degradation,
thermal
viscoelastic
properties,
surface
hydrophilicity
were
performed
contrast
properties
blends.
DSC,
DMA,
FTIR
selected
degraded
PCL/PEO
specimens
following
mass
loss
studies.
results
showed
that
adding
PEO
reduced
viscosity-torque
temperature
while
increasing
hydrophilicity,
optimizing
blend
soft
applications
could
contribute
development
more
effective
biocompatible
regeneration.
Polymers,
Год журнала:
2022,
Номер
14(16), С. 3266 - 3266
Опубликована: Авг. 11, 2022
Bleeding
control
plays
a
very
important
role
in
worldwide
healthcare,
which
also
promotes
research
and
development
of
wound
dressings.
The
healing
process
involves
four
stages
hemostasis,
inflammation,
proliferation
remodeling,
is
complex
process,
dressings
play
huge
it.
Electrospinning
technology
simple
to
operate.
Electrospun
nanofibers
have
high
specific
surface
area,
porosity,
oxygen
permeability,
excellent
mechanical
properties,
show
great
utilization
value
the
manufacture
As
one
most
popular
reactive
functional
synthetic
polymers,
polyacrylonitrile
(PAN)
frequently
explored
create
for
wide
variety
applications.
In
recent
years,
researchers
invested
application
PAN
Research
on
spun
reviewed,
future
directions
prospects
electrospun
are
proposed.
Materials,
Год журнала:
2023,
Номер
16(15), С. 5459 - 5459
Опубликована: Авг. 3, 2023
The
treatment
of
skin
wounds
caused
by
trauma
and
pathophysiological
disorders
has
been
a
growing
healthcare
challenge,
posing
great
economic
burden
worldwide.
use
appropriate
wound
dressings
can
help
to
facilitate
the
repair
healing
rate
defective
skin.
Natural
polymer
biomaterials
such
as
collagen
hyaluronic
acid
with
excellent
biocompatibility
have
shown
promote
restoration
However,
low
mechanical
properties
fast
degradation
limited
their
applications.
Skin
based
on
biodegradable
biocompatible
synthetic
polymers
not
only
overcome
shortcomings
natural
but
also
possess
favorable
for
applications
in
wounds.
Herein,
we
listed
several
used
dressing
materials,
PVA,
PCL,
PLA,
PLGA,
PU,
PEO/PEG,
focusing
composition,
fabrication
techniques,
functions
promoting
healing.
Additionally,
future
development
prospects
polymer-based
are
put
forward.
Our
review
aims
provide
new
insights
further
using
polymers.
Materials Today Bio,
Год журнала:
2023,
Номер
20, С. 100614 - 100614
Опубликована: Март 22, 2023
Repairing
central
nervous
system
(CNS)
is
difficult
due
to
the
inability
of
neurons
recover
after
damage.
A
clinically
acceptable
treatment
promote
CNS
functional
recovery
and
regeneration
currently
unavailable.
According
recent
studies,
injectable
hydrogels
as
biodegradable
scaffolds
for
tissue
engineering
have
exceptionally
desirable
attributes.
Hydrogel
has
a
biomimetic
structure
similar
extracellular
matrix,
hence
been
considered
3D
scaffold
regeneration.
An
interesting
new
type
hydrogel,
hydrogels,
can
be
injected
into
target
areas
with
little
invasiveness
imitate
several
aspects
CNS.
Injectable
are
being
researched
therapeutic
agents
because
they
may
numerous
properties
tissues
reduce
subsequent
injury
regenerate
neural
tissue.
Because
their
less
adverse
effects
cost,
easier
use
implantation
pain,
faster
capacity,
more
than
non-injectable
hydrogels.
This
article
discusses
pathophysiology
kinds
brain
spinal
cord
engineering,
paying
particular
emphasis
experimental
studies.
Biomaterials Science,
Год журнала:
2023,
Номер
11(9), С. 3051 - 3076
Опубликована: Янв. 1, 2023
This
review
offers
systematic
considerations
of
material
design
principles
and
fabrication
techniques
for
biomimetic
skin
tissue
engineering
scaffolds.
Biomedicine & Pharmacotherapy,
Год журнала:
2022,
Номер
157, С. 113996 - 113996
Опубликована: Ноя. 15, 2022
A
Non-healing
infected
wound
is
an
ever-growing
global
epidemic,
with
increasing
burden
of
mortality
rates
and
management
costs.
The
problems
chronic
infections
their
outcomes
will
continue
as
long
underlying
causes
like
diabetic
wounds
grow
spread.
Commercial
therapies
employed
have
limited
potential
that
inhibits
pivotal
functions
tissue
re-epithelialization
properties
resulting
in
infections.
Nanomaterial
based
drug
delivery
formulations
involving
biological
macromolecules
are
developing
areas
interest
healing
applications
which
utilized
the
skin
cost-effective
preparations.
Research
conducted
on
nanofibers
has
shown
enhanced
establishment
improved
cell
proliferation
growth
bioactive
organic
molecules
at
site.
However,
targeted
anti-scarring
regeneration
aspects
not
been
updated
discussed
case
macromolecule
impregnated
nanofibrous
mats.
Hence,
this
review
focuses
brief
concepts
management,
therapeutic
commercialized
dressings
currently
available
field
care,
effective
electrospun
different
advancement
nanomaterials
for
engineering
discussed.
These
new
findings
pave
way
producing
high
scaffolds
delivery.
International Journal of Nanomedicine,
Год журнала:
2022,
Номер
Volume 17, С. 3913 - 3931
Опубликована: Сен. 1, 2022
As
a
type
of
biological
macromolecule,
natural
polysaccharides
have
been
widely
used
in
wound
healing
due
to
their
low
toxicity,
good
biocompatibility,
degradability
and
reproducibility.Electrospinning
is
versatile
simple
technique
for
producing
continuous
nanoscale
fibers
from
variety
synthetic
polymers.The
application
electrospun
nanofibers
as
dressings
has
made
great
progress
they
are
considered
one
the
most
effective
dressings.This
paper
reviews
preparation
polysaccharide
by
electrospinning
prospects
field
healing.A
nanofibers,
including
chitosan,
starch,
alginate,
hyaluronic
acid
introduced.The
strategy
functions
promoting
summarized.In
addition,
future
challenges
also
discussed.
