Journal of Materials Chemistry B,
Год журнала:
2024,
Номер
12(14), С. 3453 - 3468
Опубликована: Янв. 1, 2024
Agar
and
oxidized
bacterial
cellulose
based
cryogels
are
promising
biomaterials
in
the
field
of
hemostatic
dressing,
offering
superabsorbent
properties,
rapid
blood
clotting,
excellent
biocompatibility.
The
care
and
rehabilitation
of
acute
chronic
wounds
have
a
significant
social
economic
impact
on
patients
global
health.
This
burden
is
primarily
due
to
the
adverse
effects
infections,
prolonged
recovery,
associated
treatment
costs.
Chronic
can
be
treated
with
variety
approaches,
which
include
surgery,
negative
pressure
wound
therapy,
dressings,
hyperbaric
oxygen
therapy.
However,
each
these
strategies
has
an
array
limitations.
existing
dry
dressings
lack
functionality
in
promoting
healing
exacerbating
pain
by
adhering
wound.
Hydrogels,
are
commonly
polymer-based
swell
water,
been
proposed
as
potential
remedies
their
ability
provide
moist
environment
that
facilitates
healing.
Their
unique
composition
enables
them
absorb
exudates,
exhibit
shape
adaptability,
modified
incorporate
active
compounds
such
growth
factors
antibacterial
compounds.
review
provides
updated
discussion
leading
natural
synthetic
hydrogels
utilized
healing,
details
latest
advancements
hydrogel
technology,
explores
alternate
approaches
this
field.
Search
engines
Scopus,
PubMed,
Science
Direct,
Web
were
advances
applications
over
last
fifteen
years.
Polymers,
Год журнала:
2023,
Номер
15(9), С. 2000 - 2000
Опубликована: Апрель 23, 2023
One
of
the
most
advanced,
promising,
and
commercially
viable
research
issues
in
world
hydrogel
dressing
is
gaining
functionality
to
achieve
improved
therapeutic
impact
or
even
intelligent
wound
repair.
In
addition
merits
ordinary
dressings,
functional
dressings
can
adjust
their
chemical/physical
properties
satisfy
different
types,
carry
out
corresponding
reactions
actively
create
a
healing
environment
conducive
repair,
also
control
drug
release
provide
long-lasting
benefit.
Although
lot
in-depth
has
been
conducted
over
last
few
decades,
very
studies
have
properly
summarized.
order
give
researchers
basic
blueprint
for
designing
motivate
them
develop
ever-more
we
summarized
development
recent
years,
as
well
current
situation
future
trends,
light
preparation
mechanisms
effects.
Pharmaceutics,
Год журнала:
2023,
Номер
15(7), С. 1836 - 1836
Опубликована: Июнь 27, 2023
Cryogels,
composed
of
synthetic
and
natural
materials,
have
emerged
as
versatile
biomaterials
with
applications
in
tissue
engineering,
controlled
drug
delivery,
regenerative
medicine,
therapeutics.
However,
optimizing
cryogel
properties,
such
mechanical
strength
release
profiles,
remains
challenging.
To
advance
the
field,
researchers
are
exploring
advanced
manufacturing
techniques,
biomimetic
design,
addressing
long-term
stability.
Combination
therapies
delivery
systems
using
cryogels
show
promise.
In
vivo
evaluation
clinical
trials
crucial
for
safety
efficacy.
Overcoming
practical
challenges,
including
scalability,
structural
integrity,
mass
transfer
constraints,
biocompatibility,
seamless
integration,
cost-effectiveness,
is
essential.
By
these
can
transform
biomedical
innovative
biomaterials.
Biomedicine & Pharmacotherapy,
Год журнала:
2023,
Номер
168, С. 115695 - 115695
Опубликована: Окт. 14, 2023
The
convergence
of
carbohydrate
polymers
and
metal
nanoparticles
(MNPs)
holds
great
promise
for
biomedical
applications.
Researchers
aim
to
exploit
the
capability
matrices
modulate
physicochemical
properties
MNPs,
promote
their
therapeutic
efficiency,
improve
targeted
drug
delivery,
enhance
biocompatibility.
Therefore,
understanding
various
attributes
both
carbohydrates
MNPs
is
key
harnessing
them
many
distinct
types
carbohydrate-MNP
systems
confer
unique
capabilities
wound
healing,
tissue
engineering,
cancer
treatment,
even
food
packaging.
Here,
we
introduce
physicochemical/biological
discuss
potentials
shortcomings
(alone
in
combination)
We
then
offer
an
overview
on
how
they
can
be
utilized
outcomes.
Last
but
not
least,
future
perspectives
toward
application
such
are
highlighted.