The relationship between polysaccharide structure and its antioxidant activity needs to be systematically elucidated

International Journal of Biological Macromolecules, Год журнала: 2024, Номер 270, С. 132391 - 132391

Опубликована: Май 17, 2024

Язык: Английский

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Insights into the molecular mechanisms, structure-activity relationships and application prospects of polysaccharides by regulating Nrf2-mediated antioxidant response

Carbohydrate Polymers, Год журнала: 2024, Номер 333, С. 122003 - 122003

Опубликована: Фев. 27, 2024

Язык: Английский

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Study on characterization of Bupleurum chinense polysaccharides with antioxidant mechanisms focus on ROS relative signaling pathways and anti-aging evaluation in vivo model

International Journal of Biological Macromolecules, Год журнала: 2024, Номер 266, С. 131171 - 131171

Опубликована: Апрель 2, 2024

Язык: Английский

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A polysaccharide from Morchella esculenta mycelia: Structural characterization and protective effect on antioxidant stress on PC12 cells against H2O2-induced oxidative damage

International Journal of Biological Macromolecules, Год журнала: 2025, Номер 298, С. 139886 - 139886

Опубликована: Янв. 14, 2025

Язык: Английский

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Structural characterizations and antiaging activities of hydrolyzed low-molecular-weight polysaccharides from Polygoni Multiflori Radix Praeparata

Carbohydrate Polymers, Год журнала: 2025, Номер 356, С. 123381 - 123381

Опубликована: Фев. 14, 2025

Язык: Английский

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Glucomannogalactan inhibits senescence by promoting nuclear translocation of NRF2

International Journal of Biological Macromolecules, Год журнала: 2025, Номер 305, С. 141059 - 141059

Опубликована: Фев. 15, 2025

Язык: Английский

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Structural Characterization of Galactoglucomannan from Medicinal Fungus Hypocrella bambusae and Its Protective Effects on Drosophila Intestinal Injury

Carbohydrate Polymer Technologies and Applications, Год журнала: 2025, Номер unknown, С. 100801 - 100801

Опубликована: Апрель 1, 2025

Язык: Английский

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Dietary Oligosaccharides Isolated from Coix Seed Mitigate Hyperuricemia through Modulation of Lipid Metabolites and Intestinal Homeostasis

Journal of Agricultural and Food Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Фев. 10, 2025

Hyperuricemia (HUA) is a prevalent metabolic disorder associated with chronic disease, posing significant global health challenges. Coix seed, traditional cereal, has shown therapeutic potential against HUA, oligosaccharides serving as its primary active components. However, the mechanisms of seed in HUA management remain underexplored. In this study, novel oligosaccharide was isolated from (CSO) through enzymatic hydrolysis and column chromatography. Structural analysis revealed that CSO primarily composed glucose, backbone →4)-β-Glcp-(1→ linkages. exhibited hypouricemic effects both adenosine-induced HK-2 cells mice by inhibiting XOD activity regulating urate transporter expression. Furthermore, restored lipid imbalances, particularly PS PC, modulated gut microbiota increasing Ruminococcus, Akkermansia, Lachnospiraceae abundance to alleviate HUA-related systemic disturbances. Importantly, alleviated HUA-induced renal injury downregulating IL-6/JAK2/STAT3 signaling pathway. This study provided meaningful evidence supporting effect on offered new directions for natural interventions health.

Язык: Английский

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Structural characterization of the polysaccharides from Atractylodes chinensis (DC.) Koidz. and the protective effection against alcohol-induced intestinal injury in rats

International Journal of Biological Macromolecules, Год журнала: 2024, Номер 282, С. 136641 - 136641

Опубликована: Окт. 18, 2024

Язык: Английский

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Structural characterization, anti-aging activity and mechanisms investigation in vivo of a polysaccharide from Anthriscus sylvestris

International Journal of Biological Macromolecules, Год журнала: 2024, Номер 279, С. 135256 - 135256

Опубликована: Сен. 2, 2024

Язык: Английский

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