Alisma plantago-aquatica polysaccharides ameliorate acetaminophen-induced acute liver injury by regulating hepatic metabolic profiles and modulating gut microbiota DOI
Peng Lei, Xiaoge Li, Lei Jiang

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 285, P. 138345 - 138345

Published: Dec. 3, 2024

Language: Английский

The relationship between polysaccharide structure and its antioxidant activity needs to be systematically elucidated DOI
Nuo Chen,

Tingyue Jiang,

Jianxin Xu

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 270, P. 132391 - 132391

Published: May 17, 2024

Language: Английский

Citations

50

Insights into the molecular mechanisms, structure-activity relationships and application prospects of polysaccharides by regulating Nrf2-mediated antioxidant response DOI
Nuo Chen,

Mei-Fen Hu,

Tingyue Jiang

et al.

Carbohydrate Polymers, Journal Year: 2024, Volume and Issue: 333, P. 122003 - 122003

Published: Feb. 27, 2024

Language: Английский

Citations

28

Study on characterization of Bupleurum chinense polysaccharides with antioxidant mechanisms focus on ROS relative signaling pathways and anti-aging evaluation in vivo model DOI

Anqi Feng,

Ziwei Zhao,

Changfeng Liu

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 266, P. 131171 - 131171

Published: April 2, 2024

Language: Английский

Citations

7

A polysaccharide from Morchella esculenta mycelia: Structural characterization and protective effect on antioxidant stress on PC12 cells against H2O2-induced oxidative damage DOI

Xintao Chen,

Wu Lei, Y. B. Lei

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: 298, P. 139886 - 139886

Published: Jan. 14, 2025

Language: Английский

Citations

0

Structural characterizations and antiaging activities of hydrolyzed low-molecular-weight polysaccharides from Polygoni Multiflori Radix Praeparata DOI
Xu We, Xuejian Li,

Yu-Sen Zhong

et al.

Carbohydrate Polymers, Journal Year: 2025, Volume and Issue: 356, P. 123381 - 123381

Published: Feb. 14, 2025

Language: Английский

Citations

0

Glucomannogalactan inhibits senescence by promoting nuclear translocation of NRF2 DOI
Zhenhua Liang, Qi Tang,

Haiyang Liang

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: 305, P. 141059 - 141059

Published: Feb. 15, 2025

Language: Английский

Citations

0

Structural Characterization of Galactoglucomannan from Medicinal Fungus Hypocrella bambusae and Its Protective Effects on Drosophila Intestinal Injury DOI Creative Commons
Juan Fang, Yin Chen, Qiong Wang

et al.

Carbohydrate Polymer Technologies and Applications, Journal Year: 2025, Volume and Issue: unknown, P. 100801 - 100801

Published: April 1, 2025

Language: Английский

Citations

0

Dietary Oligosaccharides Isolated from Coix Seed Mitigate Hyperuricemia through Modulation of Lipid Metabolites and Intestinal Homeostasis DOI

Guozhen Wu,

Hongjing Dong, Tao Li

et al.

Journal of Agricultural and Food Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 10, 2025

Hyperuricemia (HUA) is a prevalent metabolic disorder associated with chronic disease, posing significant global health challenges. Coix seed, traditional cereal, has shown therapeutic potential against HUA, oligosaccharides serving as its primary active components. However, the mechanisms of seed in HUA management remain underexplored. In this study, novel oligosaccharide was isolated from (CSO) through enzymatic hydrolysis and column chromatography. Structural analysis revealed that CSO primarily composed glucose, backbone →4)-β-Glcp-(1→ linkages. exhibited hypouricemic effects both adenosine-induced HK-2 cells mice by inhibiting XOD activity regulating urate transporter expression. Furthermore, restored lipid imbalances, particularly PS PC, modulated gut microbiota increasing Ruminococcus, Akkermansia, Lachnospiraceae abundance to alleviate HUA-related systemic disturbances. Importantly, alleviated HUA-induced renal injury downregulating IL-6/JAK2/STAT3 signaling pathway. This study provided meaningful evidence supporting effect on offered new directions for natural interventions health.

Language: Английский

Citations

0

Structural characterization of the polysaccharides from Atractylodes chinensis (DC.) Koidz. and the protective effection against alcohol-induced intestinal injury in rats DOI

Jin Sun,

Yuxin Jiang, Bo Wang

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 282, P. 136641 - 136641

Published: Oct. 18, 2024

Language: Английский

Citations

3

Structural characterization, anti-aging activity and mechanisms investigation in vivo of a polysaccharide from Anthriscus sylvestris DOI
Xiaoyun Ji,

Haimeng Luo,

Xianyan Li

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 279, P. 135256 - 135256

Published: Sept. 2, 2024

Language: Английский

Citations

2