Extraction and characterization of chitosan from Eupolyphaga sinensis Walker and its application in the preparation of electrospinning nanofiber membranes DOI

Fuchen Jiang,

Xuebo Li, Yun Duan

и другие.

Colloids and Surfaces B Biointerfaces, Год журнала: 2022, Номер 222, С. 113030 - 113030

Опубликована: Ноя. 21, 2022

Язык: Английский

An Injectable Antibiotic Hydrogel that Scavenges Proinflammatory Factors for the Treatment of Severe Abdominal Trauma DOI
Chao Yang, Jianati Dawulieti,

Kunbao Zhang

и другие.

Advanced Functional Materials, Год журнала: 2022, Номер 32(27)

Опубликована: Апрель 7, 2022

Abstract Bacterial infection and excessive inflammation following abdominal injury can cause life‐threatening complications that lead to multiple organ failure death. Removing bacteria proinflammatory factors—which are predominantly negatively charged—from the wound site with a cationic, antibiotic‐containing hydrogel dressing is therefore promising treatment approach for severe trauma. Here an injectable, self‐healing composed of gel‐forming glycosaminoglycan oxidized chondroitin sulfate (OCS), cationic polyethylenimine (PEI), antibiotic tobramycin (Tob) via Schiff's base reaction developed. Compared hydrogels lacking either PEI or Tob, only Tob/PEI/OCS exhibit large binding capacity negatively‐charged factors including cell‐free DNA, lipopolysaccharides, TNF‐α, high mobility group box 1 protein, reduction in bacterial populations vitro. In murine model trauma, exhibits good biodegradability biosafety, reduced local systemic infection, prevents failure, resulting 100% survival. This thus biomaterial preventing improving outcomes

Язык: Английский

Процитировано

61
Tumor Therapy Strategies Based on Microenvironment‐Specific Responsive Nanomaterials DOI

Zhaocong Zhang,

Chengwen Ding,

Tiedong Sun

и другие.

Advanced Healthcare Materials, Год журнала: 2023, Номер 12(20)

Опубликована: Март 18, 2023

Abstract The tumor microenvironment (TME) is a complex and variable region characterized by hypoxia, low pH, high redox status, overexpression of enzymes, high‐adenosine triphosphate concentrations. In recent years, with the continuous in‐depth study nanomaterials, more TME‐specific response nanomaterials are used for treatment. However, complexity TME causes different types responses various strategies mechanisms action. Aiming to systematically demonstrate advances in research on TME‐responsive this work summarizes characteristics outlines responses. Representative reaction illustrated their merits demerits analyzed. Finally, forward‐looking views TME‐response presented. It envisaged that such emerging treatment cancer expected exhibit dramatic trans‐clinical capabilities, demonstrating extensive potential diagnosis therapy cancer.

Язык: Английский

Процитировано

43
Reactive oxygen species-responsive nanocarrier ameliorates murine colitis by intervening colonic innate and adaptive immune responses DOI Creative Commons
Xiangji Yan, Lingzhang Meng, X. Zhang

и другие.

Molecular Therapy, Год журнала: 2023, Номер 31(5), С. 1383 - 1401

Опубликована: Март 10, 2023

Язык: Английский

Процитировано

33
Gallic acid: design of a pyrogallol-containing hydrogel and its biomedical applications DOI

Wu Weian,

Ye Yunxin,

Wang Ziyan

и другие.

Biomaterials Science, Год журнала: 2024, Номер 12(6), С. 1405 - 1424

Опубликована: Янв. 1, 2024

This review introduces gallic-acid hydrogels, covering their crosslinking mechanisms, physicochemical properties, synthesis methods, and biomedical applications, aiming to provide inspiration for the design of multifunctional polyphenol hydrogels.

Язык: Английский

Процитировано

16
Precise regulation of inflammation and immunosuppressive microenvironment for amplified photothermal/immunotherapy against tumour recurrence and metastasis DOI
Yanbing Wang, Caina Xu,

Meng Meng

и другие.

Nano Today, Год журнала: 2021, Номер 40, С. 101266 - 101266

Опубликована: Авг. 20, 2021

Язык: Английский

Процитировано

55
Zeolitic imidazolate framework-67 accelerates infected diabetic chronic wound healing DOI
Jinghuang Chen,

Xingfu Bao,

Meng Tian

и другие.

Chemical Engineering Journal, Год журнала: 2021, Номер 430, С. 133091 - 133091

Опубликована: Окт. 22, 2021

Язык: Английский

Процитировано

45
Cell membrane-coated nanoparticles for immunotherapy DOI
Hang Liu, Zhaohua Miao, Zhengbao Zha

и другие.

Chinese Chemical Letters, Год журнала: 2021, Номер 33(4), С. 1673 - 1680

Опубликована: Окт. 26, 2021

Язык: Английский

Процитировано

42
Synthesis, properties, and applications of chitosan hydrogels as anti-inflammatory drug delivery system DOI
Thi Thanh-Ha Nguyen, Nga H. N.,

Hy D.

и другие.

Journal of Porous Materials, Год журнала: 2022, Номер 30(2), С. 655 - 670

Опубликована: Ноя. 2, 2022

Язык: Английский

Процитировано

32
Emerging chitosan grafted essential oil components: A review on synthesis, characterization, and potential application DOI

Xiaowei Ding,

Lingyu Zhao,

Imran Mahmood Khan

и другие.

Carbohydrate Polymers, Год журнала: 2022, Номер 297, С. 120011 - 120011

Опубликована: Авг. 20, 2022

Язык: Английский

Процитировано

31
Remotely-controlled hydrogel platforms for recurrent cancer therapy DOI
Hamed Dadashi, Morteza Eskandani, Leila Roshangar

и другие.

Journal of Drug Delivery Science and Technology, Год журнала: 2023, Номер 82, С. 104354 - 104354

Опубликована: Март 9, 2023

Язык: Английский

Процитировано

19