Ferrocene/air double-mediated FeTiO₃-photocatalyzed semi-heterogeneous annulation of quinoxalin-2(1H)-ones in EtOH/H₂O

Chemical Communications, Год журнала: 2023, Номер 59(94), С. 14029 - 14032

Опубликована: Янв. 1, 2023

With both ferrocene and air as the redox catalysts, for first time, low-cost natural ilmenite (FeTiO3) was successfully used photocatalytic bond formations. Under assistance of a traceless H-bond, HCHO methylene reagent, variety imidazo[1,5-a]quinoxalinones were semi-heterogeneously photosynthesized in high yields with good functional group compatibility.

Язык: Английский

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Oxamic acids: useful precursors of carbamoyl radicals

Chemical Communications, Год журнала: 2022, Номер 58(55), С. 7593 - 7607

Опубликована: Янв. 1, 2022

Thermal, photochemical, or electrochemical-mediated decarboxylation of oxamic acids generate nucleophilic carbamoyl radicals, which react efficiently with unsaturated systems, but also amines, alcohols and thiols under oxidative conditions.

Язык: Английский

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Electrochemical radical annulation of 2-alkynyl biaryls with diselenides under catalyst- and chemical oxidant-free conditions

Chinese Chemical Letters, Год журнала: 2023, Номер 34(12), С. 108699 - 108699

Опубликована: Июнь 17, 2023

Язык: Английский

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Visible light induced four component reaction of styrene for the access of thiodifluoroesters

Chinese Chemical Letters, Год журнала: 2023, Номер 34(9), С. 108131 - 108131

Опубликована: Янв. 5, 2023

Язык: Английский

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EDA Complex-Enabled Annulation to Access CF₂-Containing Tetralones and Quinazolinones Using Persulfates as Electron Donors

The Journal of Organic Chemistry, Год журнала: 2024, Номер 89(15), С. 10614 - 10623

Опубликована: Июль 25, 2024

A photocatalyst-free and EDA complex-enabled radical cascade cyclization reaction of inactive alkenes with bromodifluoroacetamides was reported for the divergent synthesis fluorine-containing tetralones quinazolinones. In this transformation, persulfates as electron donors difluoro bromamide acceptors generate complex. This is a promising photochemical method advantages such mild conditions, simple operation, being metal-free, excellent functional group tolerance.

Язык: Английский

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Photoinduced carbamoylation reactions: unlocking new reactivities towards amide synthesis

Chemical Communications, Год журнала: 2022, Номер 58(60), С. 8322 - 8339

Опубликована: Янв. 1, 2022

In this review, we summarize the latest advances for amide moiety installation through photoinduced carbamoylation protocols.

Язык: Английский

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Transition metal-free photocatalytic radical annulation of 2-cyanoaryl acrylamides with difluoromethyl radicals to assemble 4-amino-quinolinone derivatives

Green Chemistry, Год журнала: 2023, Номер 25(16), С. 6188 - 6193

Опубликована: Янв. 1, 2023

A metal-free photocatalytic radical annulation of 2-cyanoaryl acrylamides with [CF 2 HPPh 3 ] + Br − to give 4-amino-quinolinones in good yields was developed. An easily obtained organophotocatalyst and green solvent acetone/H O were utilized the protocol.

Язык: Английский

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Recent advances in palladium-catalyzed reactions in water

Current Opinion in Green and Sustainable Chemistry, Год журнала: 2023, Номер 40, С. 100778 - 100778

Опубликована: Фев. 6, 2023

Язык: Английский

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Cascade Cyclizations Triggered by Photochemically Generated Carbamoyl Radicals Derived from Alkyl Amines

The Journal of Organic Chemistry, Год журнала: 2023, Номер 88(16), С. 11801 - 11808

Опубликована: Авг. 9, 2023

We report on a visible light-mediated cascade carbamoylation/cyclization of acrylamides using dihydropyridyl carbamoyl donors derived from alkyl amines. Diversely selected including 2-cyano-N-arylacrylamides, indolyl- and benzimidazolyl acrylamides, 2-alkynyl-N-aryl participate in this reaction, providing products good yields. The highlights photochemical method include the application amine-derived donors, peroxide-free reaction conditions, broad scope.

Язык: Английский

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Persulfate-Promoted Carbamoylation/Cyclization of Alkenes: Synthesis of Amide-Containing Quinazolinones

Molecules, Год журнала: 2024, Номер 29(5), С. 997 - 997

Опубликована: Фев. 25, 2024

The incorporation of amide groups into biologically active molecules has been proven to be an efficient strategy for drug design and discovery. In this study, we present a simple practical method the synthesis amide-containing quinazolin-4(3H)-ones under transition-metal-free conditions. This is achieved through carbamoyl-radical-triggered cascade cyclization N3-alkenyl-tethered quinazolinones. Notably, carbamoyl radical generated in situ from oxidative decarboxylative process oxamic acids presence (NH4)2S2O8.

Язык: Английский

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