A Programmable Microfluidic Paper-Based Analytical Device for Simultaneous Colorimetric and Photothermal Visual Sensing of Multiple Enzyme Activities

Analytical Chemistry, Год журнала: 2024, Номер 96(29), С. 12181 - 12188

Опубликована: Июль 8, 2024

New strategies for the simultaneous and portable detection of multiple enzyme activities are highly desirable clinical diagnosis home care. However, methods developed thus far generally suffer from high costs, cumbersome procedures, heavy reliance on large-scale instruments. To satisfy actual requirements rapid, accurate, on-site activities, we report herein a smartphone-assisted programmable microfluidic paper-based analytical device (μPAD) that utilizes colorimetric photothermal signals simultaneous, visual quantitative alkaline phosphatase (ALP) butyrylcholinesterase (BChE). Specifically, operation this μPAD sensing platform is based two sequential steps. Cobalt-doped mesoporous cerium oxide (Co-m-CeO

Язык: Английский

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Optical and Catalytic Properties of Nanozymes for Colorimetric Biosensors: Advantages, Limitations, and Perspectives

Advanced Optical Materials, Год журнала: 2024, Номер unknown

Опубликована: Сен. 16, 2024

Abstract Detection of colorimetric signals is commonly used in various analytical methods and for testing non‐laboratory resource‐limited settings. The performance assays largely based on nanoparticles their unique optical properties. Multifunctional combining enzyme‐like catalytic properties—known as nanozymes—hold great promise applications signal‐generating labels. However, the extensive focus properties leaves overlooked. In this article, use nanozymes reviewed relying inherent nanozymes, detection a catalytically‐formed product, changes caused by product. impact extinction coefficient reaction products, well kinetic parameters sensitivity limit assays, are quantitatively evaluated. Finally, existing limitations prospects biosensors summarized.

Язык: Английский

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Prospects for the use of nanozyme-based electrochemical and colorimetric sensors for antibiotic detection

Talanta, Год журнала: 2025, Номер 286, С. 127524 - 127524

Опубликована: Янв. 7, 2025

Язык: Английский

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Hollow FeNi Prussian blue nanocages with enhanced peroxidase-mimicking activity for colorimetric detection of mercury ions and L-cysteine

Chemical Engineering Journal, Год журнала: 2025, Номер unknown, С. 161080 - 161080

Опубликована: Фев. 1, 2025

Язык: Английский

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Recent advances of nanozyme-enhanced lateral flow assay sensing in clinic diagnosis

Microchemical Journal, Год журнала: 2024, Номер 206, С. 111602 - 111602

Опубликована: Сен. 7, 2024

Язык: Английский

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Perylene Diimide Based Fluorescent Sensors for Aqueous Detection of Perfluorooctane Sulfonate (PFOS)

Analytica Chimica Acta, Год журнала: 2025, Номер 1341, С. 343670 - 343670

Опубликована: Янв. 15, 2025

Язык: Английский

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Discriminative ion detection of Hg2+ and Cu2+ and selective recognition of PO43− ions: Real time monitoring in food and water samples and molecular keypad lock integration

Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy, Год журнала: 2025, Номер 331, С. 125706 - 125706

Опубликована: Янв. 22, 2025

Язык: Английский

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Antibody-mimic nanozyme mediating sandwich lateral flow immunoassay with bulk and parallel catalysis for Salmonella typhimurium detection

Chemical Engineering Journal, Год журнала: 2025, Номер unknown, С. 159862 - 159862

Опубликована: Янв. 1, 2025

Язык: Английский

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Single-atom nanozyme immunoassay with electron-rich property for clinical patient cancer detection

Chemical Engineering Journal, Год журнала: 2025, Номер 506, С. 159940 - 159940

Опубликована: Янв. 1, 2025

Язык: Английский

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Immunochromatographic food control tools: New developments and practical prospects

Theory and practice of meat processing, Год журнала: 2025, Номер 9(4), С. 280 - 295

Опубликована: Янв. 20, 2025

In the modern food production technologies, tools and means of simple rapid testing raw materials, intermediate products final ready-to-consume are in high demand. This monitoring allows determining content toxic pathogenic contaminants confirms compliance objects being tested with established regulatory requirements. Mobile tests (so called test systems) provide opportunity wide range without involving specialized laboratories highly qualified specialists. Thus, systems for detection serve as useful addition to confirming instrumental analytical methods. An actively developing approach this field is using immunochromatographic strips, which strips all necessary reagents applied membrane components system. Contact strip sample tested, initiates further interactions generates recordable or visually assessable optical signal. The market based on analysis constantly growing, thus offering permanently widening choice solutions. However, recent years there has been a real boom new developments immunochromatography field, various options sensitive information capacitive systems. study systematizes these provides their comparative assessment terms prospects technological implementation practical application coming years. opportunities designing antibodies alternative receptor molecules controlling affinity selectivity recognition compounds monitored considered. advantages limitations nanodispersed markers non-optical methods registration discussed. quantitative via characterized. developed design multiplex control — simultaneous several presented. Examples integration automatic registration, processing, transfer, storage results numerous represented.

Язык: Английский

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