Chemistry - An Asian Journal,
Год журнала:
2024,
Номер
unknown
Опубликована: Ноя. 5, 2024
Abstract
Carbon
dots
(CDs)
are
carbon‐based
nanomaterials
that
have
garnered
immense
attention
owing
to
their
exceptional
photophysical
and
optoelectronic
properties.
They
been
employed
extensively
for
biomedical
imaging
phototherapy
due
superb
water
dispersibility,
low
toxicity,
outstanding
biocompatibility,
tissue
permeability.
This
review
summarizes
the
structural
classification
of
CDs,
CDs
according
precursor
sources,
luminescence
mechanism
CDs.
The
modification
in
via
various
doping
routes
is
comprehensively
reviewed,
effect
such
alterations
on
properties,
as
absorbance,
photoluminescence
(PL),
reactive
oxygen
species
generation
ability,
also
highlighted.
strives
summarize
role
cellular
fluorescence
lifetime
metabolism.
Subsequently,
recent
advancements
future
potential
nanotheranostic
agents
discussed.
Herein,
we
discussed
photothermal,
photodynamic,
synergistic
therapy
anticancer,
antiviral,
antibacterial
applications.
overall
summary
highlights
prospects
CD‐based
research
bioimaging
biomedicine.
International Journal of Nanomedicine,
Год журнала:
2024,
Номер
Volume 19, С. 5637 - 5680
Опубликована: Июнь 1, 2024
Abstract:
Photodynamic
therapy
(PDT)
is
a
non-invasive
that
has
made
significant
progress
in
treating
different
diseases,
including
cancer,
by
utilizing
new
nanotechnology
products
such
as
graphene
and
its
derivatives.
Graphene-based
materials
have
large
surface
area
photothermal
effects
thereby
making
them
suitable
candidates
for
PDT
or
photo-active
drug
carriers.
The
remarkable
photophysical
properties
of
derivates
facilitate
the
efficient
generation
reactive
oxygen
species
(ROS)
upon
light
irradiation,
which
destroys
cancer
cells.
Surface
functionalization
can
also
enhance
their
biocompatibility
anticancer
activity.
paper
delves
into
distinct
roles
played
graphene-based
photosensitizers
(PS)
carriers
while
at
same
time
considers
how
these
could
be
used
to
circumvent
resistance.
This
will
provide
readers
with
an
extensive
discussion
various
pathways
contributing
inefficiency.
Consequently,
this
comprehensive
review
underscores
vital
derivatives
may
play
emerging
strategies
treatment
other
medical
purposes.
With
better
comprehension
current
state
research
existing
challenges,
integration
holds
great
promise
developing
targeted,
effective,
personalized
treatments.
Keywords:
quantum
dots,
oxide,
research,
photosensitizers,
delivery
Advanced Healthcare Materials,
Год журнала:
2024,
Номер
unknown
Опубликована: Авг. 1, 2024
Abstract
Carbon
dots
(CDs)
with
good
optical
properties,
biocompatibility,
easy
functionalization,
and
small
size
have
attracted
more
attention
laid
a
foundation
for
their
applications
in
the
biomedicine
field.
CDs
emitted
near‐infrared
regions
(NIR‐CDs)
can
achieve
high
penetration
depth
imaging
produce
cytotoxic
substance
disease
treatment.
Therefore,
NIR‐CDs
are
promising
materials
to
realize
high‐quality
imaging‐guided
diagnostic
therapeutic
integration.
This
review
first
introduces
current
mainstream
synthesis
methods
of
by
“top–down”
“bottom–up”.
Second,
luminescence
modes
introduced,
mechanisms
based
on
carbon
core
state,
surface
molecular
crosslinking
enhanced
emission
summarized.
Third,
principles
imaging,
drug
delivery,
non‐invasive
therapeutics
introduced
from
view
diagnosis
therapy.
Finally,
prospects
challenges
biomedical
biotechnological
outlined.
Journal of the Chinese Chemical Society,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 12, 2025
Abstract
In
the
emerging
era
of
infectious
diseases,
antimicrobials
are
widely
applied
against
pathogenic
microbes
(i.e.,
bacteria,
fungus,
or
virus)
to
avoid
global
mortality.
Nonetheless,
quite
a
few
microbiome
adopted
genetic
mutations
over
extended
period
and
fostered
sustainable
resistance
towards
existing
newer
antibiotics.
Carbon
dots
(CDs)
carbon‐based
nanomaterials,
unveiled
their
potential
as
antifungal,
antibacterial,
antiviral
agents
resembled
with
ease
synthesis,
reduced
toxicity,
smart
functionalization,
high
aqueous
dispersibility,
auspicious
biocompatibility.
This
review
has
emphasized
discussion
corroborated
types
CDs
numerous
properties
tailored
biofunctionalization.
Further
article
was
featured
antiviral,
bioimaging,
biosensing,
anticancer
responsiveness
(in
vivo
in
vitro
mode)
followed
by
biocompatibility,
toxicity
assessments,
challenges,
future
prospectives.
