Blazing Carbon Dots: Unfolding its Luminescence Mechanism to Photoinduced Biomedical Applications DOI

Nirmiti Mate,

Vinita Satwani,

Pranav Tiwari

et al.

Chemistry - An Asian Journal, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 5, 2024

Abstract Carbon dots (CDs) are carbon‐based nanomaterials that have garnered immense attention owing to their exceptional photophysical and optoelectronic properties. They been employed extensively for biomedical imaging phototherapy due superb water dispersibility, low toxicity, outstanding biocompatibility, tissue permeability. This review summarizes the structural classification of CDs, CDs according precursor sources, luminescence mechanism CDs. The modification in via various doping routes is comprehensively reviewed, effect such alterations on properties, as absorbance, photoluminescence (PL), reactive oxygen species generation ability, also highlighted. strives summarize role cellular fluorescence lifetime metabolism. Subsequently, recent advancements future potential nanotheranostic agents discussed. Herein, we discussed photothermal, photodynamic, synergistic therapy anticancer, antiviral, antibacterial applications. overall summary highlights prospects CD‐based research bioimaging biomedicine.

Language: Английский

A novel silkworm excrement-derived nanomedicine integrating ferroptosis and photodynamic therapy, well-suitable for PD-L1-mediated immune checkpoint blockade DOI
Yujun Bao, Guanghao Li, Mingyang Liu

et al.

Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: 505, P. 159676 - 159676

Published: Jan. 17, 2025

Language: Английский

Citations

1

Advancements in the synthesis of carbon dots and their application in biomedicine DOI
Jia Xu,

Bing‐Bing Huang,

Chun-Mei Lai

et al.

Journal of Photochemistry and Photobiology B Biology, Journal Year: 2024, Volume and Issue: 255, P. 112920 - 112920

Published: April 21, 2024

Language: Английский

Citations

7

Graphene-Based Photodynamic Therapy and Overcoming Cancer Resistance Mechanisms: A Comprehensive Review DOI Creative Commons
Hanna Dilenko, Kateřina Tománková, Lucie Válková

et al.

International Journal of Nanomedicine, Journal Year: 2024, Volume and Issue: Volume 19, P. 5637 - 5680

Published: June 1, 2024

Abstract: Photodynamic therapy (PDT) is a non-invasive that has made significant progress in treating different diseases, including cancer, by utilizing new nanotechnology products such as graphene and its derivatives. Graphene-based materials have large surface area photothermal effects thereby making them suitable candidates for PDT or photo-active drug carriers. The remarkable photophysical properties of derivates facilitate the efficient generation reactive oxygen species (ROS) upon light irradiation, which destroys cancer cells. Surface functionalization can also enhance their biocompatibility anticancer activity. paper delves into distinct roles played graphene-based photosensitizers (PS) carriers while at same time considers how these could be used to circumvent resistance. This will provide readers with an extensive discussion various pathways contributing inefficiency. Consequently, this comprehensive review underscores vital derivatives may play emerging strategies treatment other medical purposes. With better comprehension current state research existing challenges, integration holds great promise developing targeted, effective, personalized treatments. Keywords: quantum dots, oxide, research, photosensitizers, delivery

Language: Английский

Citations

6

Carbon dots-based composites electrocatalysts in hydrogen evolution reaction and oxygen evolution reaction: A mini review DOI
Tian-Ze Li, Yuanyuan Dong, Jianjiao Zhang

et al.

International Journal of Hydrogen Energy, Journal Year: 2024, Volume and Issue: 77, P. 359 - 372

Published: June 18, 2024

Language: Английский

Citations

6

Recent progress in organic carbon dot-based photosensitizers for photodynamic cancer therapy DOI
Nguyễn Văn Nghĩa, Hoang Long Pham, Xuan Truong Nguyen

et al.

Dyes and Pigments, Journal Year: 2024, Volume and Issue: 230, P. 112359 - 112359

Published: July 27, 2024

Language: Английский

Citations

6

Advance of Near‐Infrared Emissive Carbon Dots in Diagnosis and Therapy: Synthesis, Luminescence, and Application DOI
Jing Hu,

Ziliang Zheng,

Yongzhen Yang

et al.

Advanced Healthcare Materials, Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 1, 2024

Abstract Carbon dots (CDs) with good optical properties, biocompatibility, easy functionalization, and small size have attracted more attention laid a foundation for their applications in the biomedicine field. CDs emitted near‐infrared regions (NIR‐CDs) can achieve high penetration depth imaging produce cytotoxic substance disease treatment. Therefore, NIR‐CDs are promising materials to realize high‐quality imaging‐guided diagnostic therapeutic integration. This review first introduces current mainstream synthesis methods of by “top–down” “bottom–up”. Second, luminescence modes introduced, mechanisms based on carbon core state, surface molecular crosslinking enhanced emission summarized. Third, principles imaging, drug delivery, non‐invasive therapeutics introduced from view diagnosis therapy. Finally, prospects challenges biomedical biotechnological outlined.

Language: Английский

Citations

5

Inulin-based fluorescent carbon dots as effective probes for rapid/visual detection of 3-nitrotyrosine DOI
Yaxuan Chen, Chen Wang,

Yushi Guo

et al.

Microchemical Journal, Journal Year: 2025, Volume and Issue: 209, P. 112750 - 112750

Published: Jan. 11, 2025

Language: Английский

Citations

0

Carbon dots as smart biosensing and imaging materials delving with antimicrobial, antifungal, and antiviral potentials against infectious pathogens DOI Open Access
Debashis Tripathy, Sagar Kumar Mishra, Shiba Narayan Sahu

et al.

Journal of the Chinese Chemical Society, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 12, 2025

Abstract In the emerging era of infectious diseases, antimicrobials are widely applied against pathogenic microbes (i.e., bacteria, fungus, or virus) to avoid global mortality. Nonetheless, quite a few microbiome adopted genetic mutations over extended period and fostered sustainable resistance towards existing newer antibiotics. Carbon dots (CDs) carbon‐based nanomaterials, unveiled their potential as antifungal, antibacterial, antiviral agents resembled with ease synthesis, reduced toxicity, smart functionalization, high aqueous dispersibility, auspicious biocompatibility. This review has emphasized discussion corroborated types CDs numerous properties tailored biofunctionalization. Further article was featured antiviral, bioimaging, biosensing, anticancer responsiveness (in vivo in vitro mode) followed by biocompatibility, toxicity assessments, challenges, future prospectives.

Language: Английский

Citations

0

Tailoring Versatile Nanoheterojunction-Incorporated Hydrogel Dressing for Wound Bacterial Biofilm Infection Theranostics DOI

Shuting Zhang,

Wenxuan He, Jian‐Wen Dong

et al.

ACS Nano, Journal Year: 2025, Volume and Issue: unknown

Published: March 12, 2025

Wound-infected bacterial biofilms are protected by self-secreted extracellular polymer substances (EPS), which can confer them with formidable resistance to the host's immune responses and antibiotics, thus delays in diagnosis treatment cause stubborn infections life-threatening complications. However, tailoring an integrated theranostic platform capability promptly diagnose treat wound biofilm infection still remains a challenge. Herein, versatile erbium-doped carbon dot-encapsulated zeolitic imidazolate framework-8 (Er:CDs@ZIF-8) nanoheterojunction (C@Z nano-HJ) is tailored incorporated into gelatin methacrylate/poly(N-hydroxyethyl acrylamide) (GelMA/PHEAA)-based tough sticky hydrogel dressing (GH-C@Z) achieve infection-integrated application. Stimulated acidic microenvironment of biofilm, turn-on response C@Z assists monitoring exhibiting cyan fluorescence. Meanwhile, effectively destroy EPS barrier accomplish photothermal-photodynamic-ion interference synergistic antibacterial therapy under near-infrared light. Furthermore, after effective eradication potent antioxidant properties released Er:CDs allow attenuate reactive oxygen species mitigate inflammatory responses, finally promote collagen deposition neovascularization accelerate healing. Overall, this provides insight development diagnostic therapeutic platforms for infections.

Language: Английский

Citations

0

Orange carbon dots for methylene blue detection in actual water samples, live cells and enoki mushroom DOI
Yifan Sun, Min Zheng

Microchemical Journal, Journal Year: 2025, Volume and Issue: unknown, P. 113531 - 113531

Published: April 1, 2025

Language: Английский

Citations

0